Sodium carboxymethyl cellulose

Manufactured by Sinopharm

Sourced in China

Sodium carboxymethyl cellulose is a white, odorless, and water-soluble powder that is derived from cellulose. It is a commonly used thickening, stabilizing, and emulsifying agent in various industries, including food, pharmaceuticals, and personal care products.

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Lab products found in correlation

Sodium hydroxide (naoh), by Sinopharm (4 mentions) Gelatin, by Sinopharm (2 mentions) Sodium alginate, by Sinopharm (2 mentions) Acetic acid, by Sinopharm (2 mentions) Boric acid, by Sinopharm (2 mentions) Ethyl acetate, by Sinopharm (2 mentions) Chitosan, by Sinopharm (2 mentions) Hydrochloric acid (hcl), by Sinopharm (2 mentions) Tcs sp8 cars, by Leica (1 mentions) Tecnai g2 f30, by Thermo Fisher Scientific (1 mentions) Zetasizer nano z, by Malvern Panalytical (1 mentions) S 4800, by Hitachi (1 mentions) Uv 1800, by Shimadzu (1 mentions) Ascorbic acid, by Sinopharm (1 mentions) Silver nitrate, by Sinopharm (1 mentions) Glycerol gly, by Sinopharm (1 mentions) Absolute ethanol, by Sinopharm (1 mentions) Calcium chloride cacl2, by Sinopharm (1 mentions) Adenine, by Maclin Biochemical Technology (1 mentions) Disodium tetraborate decahydrate, by Sinopharm (1 mentions)

Close spelling variants of this product

Sodium carboxymethyl cellulose (CMC-Na) (24 citations) Carboxymethyl cellulose (4 citations) Sodium cellulose (2 citations)

20 protocols using sodium carboxymethyl cellulose

Synthesis and Characterization of Silver Nanoparticles

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Carboxymethyl cellulose sodium (300–800 mPa·s), silver nitrate and ascorbic acid were purchased from Sinopharm Chemical Reagent Co. Ltd (Shanghai, China); all other reagents were of analytical grade. All the aqueous solutions were prepared with distilled and deionized water.
The instruments used in this work included the following: a magnetic stirrer from SILE (Shanghai, China), an incubator from PEIYING (Suzhou, China), a UV-vis spectrometer from SHIMADZU (UV-1800, Kyoto, Japan), a scanning electron microscope (SEM, Hitachi S-4800, Tokyo, Japan), a transmission electron microscope (TEM, FEI Tecnai G2 F30, Hillsboro, OR, US), a laser particle size analyzer (Malvern Zetasizer nano ZS, Malvern, UK), an X-ray powder diffractometer (XRD, Xpert pro MDP, PANalytical B.V., Almelo, Netherlands) and a confocal laser scanning microscope (CLSM, Leica TCS SP8 CARS, Berlin, Germany).

Shang H., Zhou Z., Wu X., Li X, & Xu Y. (2020). Sunlight-Induced Synthesis of Non-Target Biosafety Silver Nanoparticles for the Control of Rice Bacterial Diseases. Nanomaterials, 10(10), 2007.

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Biopolymer-based Antimicrobial Coatings

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Sodium alginate (SA, relative molecular weight M_r = 216.12303, viscosity η ≥ 0.02 Pa s), gelatin (G, M_r = 10,000–70,000, η ≥ 0.015 Pa s), gum acacia (A, M_r = 262.64858, η = 0.06–0.13 Pa s), carboxymethylcellulose sodium (C, M_r = 263.1976, η = 0.3–0.8 Pa s), cinnamon essential oil (CEO, density ρ = 1.045–1.070 g/mL), glycerol (Gly), calcium chloride (CaCl₂), and absolute ethanol were all purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). All chemicals were of analytical grade. Ultrapure water was prepared by the Aquaplore ultra-pure water system (Shanghai Ultrapure Industrial Co., Ltd., Shanghai, China).

Chen X., Lu L.X., Yao W.R, & Pan L. (2020). Diffusion Mechanism of Cinnamon Essential Oils Release from Calcium Alginate Based Controlled Release Films in Contact with Food Simulating Solvent. Materials, 13(24), 5679.

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Extraction and Quantification of Allopurinol

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Allopurinol tablets were procured from Shimao Tianjie Pharmaceutical (Jiangsu) Co., Ltd. Carboxymethylcellulose sodium, boric acid (Guaranteed reagent), disodium tetraborate decahydrate (Analytical Reagent), perchloric acid (Analytical Reagent), and acetic acid (Analytical Reagent) were all acquired from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Potassium oxonate and adenine were sourced from Shanghai Macklin Biochemical Technology Co., Ltd. Yeast extract and 0.9% sodium chloride injection were purchased from Shanghai Chunshi Biotechnology Co., Ltd. (Shanghai, China) and Kelun Pharmaceutical Co., Ltd. (Sichuan, China), respectively. High-performance liquid chromatography (HPLC) grade methanol was obtained from TEDIA Company Inc (USA).

Wang X., Lu H., Rong J., Sun Z., Zheng Y., Fan B, & Jia Z. (2024). PEGylated porcine–human recombinant uricase: A novel fusion protein with improved efficacy and safety for the treatment of hyperuricemia and renal complications. Open Life Sciences, 19(1), 20220799.

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Optimization of Transdermal Felbinac Formulation

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Felbinac was bought from Energy Chemical, Ltd. (Shanghai, China). Partially neutralized polyacrylate, Viscomate™ NP-800 (NP-800), was obtained from Showa Denko K.K. (Kawasaki, Japan). Glycerin, tartaric acid, DAAA, carboxymethylcellulose sodium, diisopropanolamine and sorbitol were obtained from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Purified water was prepared using a Direct-Q Ultrapure Water Purification System (Millipore Corp., Billerica, MA, USA).
Physica MCR 301 Rheometer (Anton Paar, Graz, Austria) was used to evaluate the rheological behavior of the formulations. PT-501-D peeling strength tester (Precise Test Equipment, Ltd., Dongguan, China) was used to evaluate the peeling strength of the formulations. Design-Expect^®® software 8.06 (Stat-Ease Inc., Minneapolis, MN, USA) was used to develop and optimize the formulation.

Yang J., Zhu Y., Diao Y, & Yin C. (2018). Rheological and Mechanical Analyses of Felbinac Cataplasms by Using Box–Behnken Design. Pharmaceutics, 10(3), 88.

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Carboxymethyl Cellulose Sodium Functionalization

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Carboxymethyl cellulose sodium (CP = 800–1200) was purchased from Sinopharm Co Ltd (Shanghai, China). 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide·HCl (EDC·HCl) was purchased from Maya Chemical Ltd (Jiaxing, China). PVA-124, 2-(N-morpholino)ethanesulfonic acid monohydrate (MES, 99%), N-hydroxysuccinimide (NHS, 96%) and 3-aminophenylboronic acid hydrochloride was purchased from Macklin Inc. (Shanghai, China). Other solvents and chemical reagents used in this research were analytical pure supplied by Kernel Chem. and used as received.

An H., Bo Y., Chen D., Wang Y., Wang H., He Y, & Qin J. (2020). Cellulose-based self-healing hydrogel through boronic ester bonds with excellent biocompatibility and conductivity. RSC Advances, 10(19), 11300-11310.

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Bioactive Compounds Extraction Optimization

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The fresh Lentinus edodes, Grifola frondosa, and Hericium erinaceus were purchased from the Gouzhuang Farmers' Market in Hangzhou and pulverized into powder. Ganoderma lucidum extract residue was provided by Zhejiang WisePlus Health Technology Corporation Ltd. NaOH, HCl, Na₂HPO₄·12H₂O, NaHPO₄·H₂O, sodium taurocholate, sodium carboxymethyl cellulose, DNS, and soluble starch were purchased from Sinopharm Chemical Reagent Corporation Ltd. (Shanghai, China). Neutral protease, alpha amylase, and lipase were purchased from Beijing Gao Ruisen Technology Corporation Ltd. Corn oil was purchased from Shanghai Maclean Reagent Corporation Ltd. All the other chemicals used in this study were of analytical grade.

Tian B., Pan Y., Wang J., Cai M., Ye B., Yang K, & Sun P. (2022). Insoluble Dietary Fibers From By-Products of Edible Fungi Industry: Basic Structure, Physicochemical Properties, and Their Effects on Energy Intake. Frontiers in Nutrition, 9, 851228.

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Purification and Characterization of Nardosinone

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The purity of nardosinone was greater than 98% (UHPLC, 254 nm) and it was purchased from Chengdu Push Bio-technology (Chengdu, China, Lot No. PS010660). HPLC-grade formic acid (Lot No. 212271), UHPLC-grade acetonitrile (Lot No. 207296), and HPLC-grade methanol (Lot No. 203511) were purchased from Thermo Fisher Scientific (Waltham, MA, USA); HPLC-grade ethanol (Lot No. 32061) was purchased from Beijing Tong Guang Fine Chemicals Company (Beijing, China). Sodium carboxymethyl cellulose (Lot No. A18105) was purchased from Sinopharm Chemical Reagents Co., Ltd. (Shanghai, China). Ultrapure water was prepared using a Milli-Q Integral 3 ultrapure water machine (Millipore, Billerica, MA, USA).

Zhang J., Lv Y., Zhang J., Bai Y.S., Li M.Y., Wang S.Q., Wang L.L., Liu G.X., Xu F., Shang M.Y, & Cai S.Q. (2022). Analysis of In Vivo Existence Forms of Nardosinone in Mice by UHPLC-Q-TOF-MS Technique. Molecules, 27(21), 7267.

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Microglia Elimination in EAE Model

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The drug was prepared following TargetMol's protocol (No.1303420‐67‐8). Briefly, PLX5622 stock was dissolved in dimethyl sulfoxide (DMSO) at a concentration of 79 mg mL⁻¹ (199.79 × 10⁻³ m); 0.5% sodium carboxymethyl cellulose (Sinopharm Chemical Reagent Co. Ltd.) was prepared to make a diluent. On each dosing day, PLX5622 stock was diluted tenfold by adding 1 volume of drug stock (79 mg mL⁻¹) in 9 volumes of diluent, making a working solution at 7.9 mg mL⁻¹. Vehicle solution was prepared with a mix of diluent and DMSO. To eliminate microglia in EAE model, PLX5622 of indicated concentration was intragastric administrated every day since 14 d before the MOG immunization until sacrificed.

Yu Z., Fang X., Liu W., Sun R., Zhou J., Pu Y., Zhao M., Sun D., Xiang Z., Liu P., Ding Y., Cao L, & He C. (2022). Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination. Advanced Science, 9(24), 2105442.

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Extraction and Characterization of Pentylenetetrazol-Containing Insect Samples

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Pentylenetetrazol (PTZ) was obtained from Aladdin (Aladdin, Shanghai, China). Sodium chloride (BDH) was purchased by Zhejiang Kancheer Pharmaceutical Co., Ltd. (Dongyang, China). Chromatographic-grade methanol was purchased from Merck (Rahway, NJ, USA). Petroleum ether, chloroform ethanol, ethyl acetate, and sodium carboxymethylcellulose were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). The insect sample was collected from Ping Yi country in the Shan Dong province and was then identified and authenticated by Guo ZengXi, a Chinese Medicine Practitioner.

Wang Q., Wang R., Zheng C., Zhang L., Meng H., Zhang Y., Ma L., Chen B, & Wang J. (2022). Anticonvulsant Activity of Bombyx batryticatus and Analysis of Bioactive Extracts Based on UHPLC-Q-TOF MS/MS and Molecular Networking. Molecules, 27(23), 8315.

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Biomaterials Synthesis and Characterization

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Pyromellitic dianhydride (96%), ethyl alcohol (96%), 1-ethyl (3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) (93%), isopropanol (AR), o-phenylenediamine (99%) and sodium alginate (AR) were purchased from Shanghai Aladdin Biochemical Technology Co., Ltd.
Urea (AR), ferric chloride hexahydrate (AR), sodium hydroxide (99%), hydrochloric acid (GR), methanol (AR), tetrahydrofuran (AR), ammonium molybdate (AR), and sodium carboxymethyl cellulose (Degree of carboxymethylation, ≥80%) were purchased from Sinopharm Group Chemical Reagent Co. Ltd.
P-methoxy benzaldehyde (98%), vinyl acetate (98%), chloroacetic acid (98%), sodium dodecyl sulfate (95%), chitosan (Degree of deacetylation, ≥90%), and barium hydroxide (AR) were purchased from Shanghai Saan Chemical Technology Co. Ltd.

Li J., Guo M., Wang Y., Ye B., Chen Y, & Yang X. (2020). Preparation of biological sustained-release nanocapsules and explore on algae-killing properties. Journal of Advanced Research, 31, 87-96.

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