Rat human crf

Manufactured by Merck Group

Sourced in United States

The Rat/human CRF is a lab equipment product developed by Merck Group. It is designed to detect and measure the levels of corticotropin-releasing factor (CRF) in rat and human samples. CRF is a neuropeptide that plays a crucial role in the body's stress response system. The Rat/human CRF product provides a reliable and accurate tool for researchers to study the function and regulation of CRF in various biological processes.

Automatically generated - may contain errors

Lab products found in correlation

K41498, by Bio-Techne (3 mentions) Nbi35965, by Bio-Techne (2 mentions) Naloxone hydrochloride, by Merck Group (1 mentions)

3 protocols using rat human crf

Pharmacological Modulation of CRF Receptors

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The following drugs were used: rat/human CRF (Sigma-Aldrich, St. Louis, MO); CRF-R1 agonist stressin I and CRF-R1 antagonist NBI 27914 (Bio-Techne GmbH, Wiesbaden-Nordenstadt, Germany); CRF-R2 agonist urocortin-2 (Ucn-2), CRF-R2 antagonist K41498 (Bio-Techne GmbH, Wiesbaden-Nordenstadt, Germany); naloxone hydrochloride (Sigma-Aldrich, St. Louis, MO). Doses were calculated as the free base and drugs were dissolved in isotonic saline as vehicle. The volume of i.c.v. drug administration was 10 µl. For each dose a separate group of animals (n = 6) was used. Drugs were administered under brief isoflurane anesthesia.

Mousa S.A., Khalefa B.I., Shaqura M., Al-Madol M., Treskatsch S, & Schäfer M. (2022). Superior control of inflammatory pain by corticotropin-releasing factor receptor 1 via opioid peptides in distinct pain-relevant brain areas. Journal of Neuroinflammation, 19, 148.

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Pharmacological Modulation of CRF Receptors

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The following drugs were used: rat/human CRF (Sigma-Aldrich, St. Louis, MO, USA); CRF-R2 agonist urocortin-2 (Ucn-2), CRF-R2 antagonist K41498; CRF-R1 antagonist NBI35965 (Bio-Techne GmbH, Wiesbaden-Nordenstadt, Germany). Doses were calculated as the free base and drugs were dissolved in isotonic saline as vehicle. For each dose a separate group of animals (n = 6) was used. Drugs were administered during brief isoflurane anesthesia.

Mousa S.A., Shaqura M., Khalefa B.I., Li L., Al-Madol M., Treskatsch S, & Schäfer M. (2021). Functional and Anatomical Characterization of Corticotropin-Releasing Factor Receptor Subtypes of the Rat Spinal Cord Involved in Somatic Pain Relief. Molecular Neurobiology, 58(11), 5459-5472.

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Pharmacological Modulation of CRF Receptors

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Mousa S.A., Shaqura M., Khalefa B.I., Li L., Al-Madol M.A., Treskatsch S., & Schäfer M. (2021). Functional and anatomical characterization of corticotropin-releasing factor receptor subtypes of the rat spinal cord involved in somatic pain relief.

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