Noradrenaline bitartrate

Manufactured by Bio-Techne

Noradrenaline bitartrate is a laboratory reagent used in various research applications. It is a salt of noradrenaline, also known as norepinephrine, which is a neurotransmitter and hormone. The primary function of noradrenaline bitartrate is to serve as a standard or reference compound for the identification and quantification of noradrenaline in biological samples.

Automatically generated - may contain errors

Lab products found in correlation

Propranolol hydrochloride, by Bio-Techne (1 mentions) Prazosin hydrochloride, by Bio-Techne (1 mentions) Cgp 55845a, by Bio-Techne (1 mentions) Dl ap5, by Bio-Techne (1 mentions) Pclamp, by Molecular Devices (1 mentions) Isovalerate, by Merck Group (1 mentions) Prestoblue cell viability reagent, by Thermo Fisher Scientific (1 mentions) Infinite f200 pro, by Tecan (1 mentions)

Close spelling variants of this product

Noradrenaline

2 protocols using noradrenaline bitartrate

Electrophysiological Profiling of Central Amygdala Neurons

Cited 3 times

Check if the same lab product or an alternative is used in the 5 most similar protocols

Rats were anesthetized and brain slices prepared (25 (link),27 (link)). Neuronal intrinsic membrane properties and excitability, spontaneous/miniature inhibitory postsynaptic currents (s/mIPSCs) and spontaneous cell firing were recorded in 236 cells in the medial central amygdala (CeA) (25 (link)–28 (link)). Each experiment includes data from a minimum of 4 rats, with 1–2 cells per animal. Recordings were analyzed with pClamp (Molecular Devices, Sunnyvale, CA), MiniAnalysis (Synaptosoft Inc., Fort Lee, NJ) or NeuroExpress software by Dr. A. Szucs (26 (link),29 (link)). Cells were classified as increased, decreased, or no change based on ±20% change in the maximum drug effect from baseline.
DL-AP5, CGP 55845A, DNQX, noradrenaline bitartrate, prazosin hydrochloride and propranolol hydrochloride (Tocris, Bristol, UK); bicuculline and tetrodotoxin (TTX; Sigma. St. Louis, MO); and alcohol (Remet, La Mirada, CA) were dissolved in ACSF.

Varodayan F.P., Patel R.R., Matzeu A., Wolfe S.A., Curley D.E., Khom S., Gandhi P., Rodriguez L., Bajo M., D’Ambrosio S., Sun H., Kerr T.M., Gonzales R.A., Leggio L., Natividad L.A., Haass-Koffler C.L., Martin-Fardon R, & Roberto M. (2022). The amygdala noradrenergic system is compromised with alcohol use disorder. Biological psychiatry, 91(12), 1008-1018.

+ Open protocol

+ Expand

Metabolic Assay of Intestinal Epithelial Cells

Check if the same lab product or an alternative is used in the 5 most similar protocols

After 4 days in differentiation medium and induced with 0, 0.1, or 1 μg/mL doxycycline, confluent HIE monolayers were washed with 1× PBS. Isovalerate (Sigma-Aldrich) and noradrenaline bitartrate (Tocris Bioscience) solutions were prepared in 1× PBS and added to the HIE monolayers. Monolayers were incubated for 2 hours at 37°C and 5% CO₂. After incubation, supernatants were harvested and kept at -20°C for downstream analysis. PrestoBlue Cell Viability Reagent (ThermoFisher Scientific), a resazurin-based assay, was used according to the manufacturer’s recommended protocols. Fluorescence intensity of reduced resazurin (560–610 nm, Infinite F200Pro; Tecan, Mannedorf, CHF) measures metabolic activity of the cells and was used as an indication of cell viability.

Chang-Graham A.L., Danhof H.A., Engevik M.A., Tomaro-Duchesneau C., Karandikar U.C., Estes M.K., Versalovic J., Britton R.A, & Hyser J.M. (2019). Human Intestinal Enteroids With Inducible Neurogenin-3 Expression as a Novel Model of Gut Hormone Secretion. Cellular and Molecular Gastroenterology and Hepatology, 8(2), 209-229.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!