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Il 33

Manufactured by Novus Biologicals

IL-33 is a cytokine that belongs to the IL-1 family. It plays a role in the immune response and inflammatory processes.

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2 protocols using il 33

1

Plasma-based Biomarker Assessment

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IL-33 (Novus Biologicals) and ACE2 DuoSet ELISA (R&D) were performed on frozen plasma samples of patients and HCs according to the manufacturing protocol.
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2

Characterization of ST2-Mediated Signaling

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All drugs were obtained from Sigma-Aldrich unless otherwise indicated. IL-33 was obtained from Novus Biologicals. The ST2 neutralizing antibody was obtained from R&D System. The soluble form of ST2 (sST2) was obtained from Cohesion Biosciences. KT-5720 was obtained from Tocris. GS9973 and R406 were obtained from Selleck. JX-401 was obtained from Abcam. Stock solutions of KT-5720, AG490, R406, GS9973, LY294002, Akt inhibitor III, SB203580, SB202474 and JX401 were prepared in dimethyl sulfoxide (DMSO). The final concentration of DMSO in the bath (maximum of 0.05%) had no functional effects on the currents measured.
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