Recombinant cxcl12 sdf 1α

Manufactured by Thermo Fisher Scientific

Sourced in United States

Recombinant (CXCL12) SDF-1α is a chemokine protein produced through recombinant DNA technology. It functions as a chemoattractant, playing a role in the migration and trafficking of various cell types.

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Lab products found in correlation

Amd3100, by Merck Group (2 mentions) Nystatin, by Merck Group (1 mentions) Anti zeb1, by Cell Signaling Technology (1 mentions) Anti e cadherin, by Cell Signaling Technology (1 mentions) Stattic, by Selleck Chemicals (1 mentions) Anti stat3, by Cell Signaling Technology (1 mentions) Anti cxcr4 antibody, by Abcam (1 mentions) Anti phosphor stat3, by Cell Signaling Technology (1 mentions) Pha 665752, by Merck Group (1 mentions) Anti vimentin, by Cell Signaling Technology (1 mentions) Anti snail, by Abcam (1 mentions) Anti twist2, by Abcam (1 mentions) Bay11 7082, by Merck Group (1 mentions) Rabbit anti cxcr4 antibody, by Abcam (1 mentions) C225 cetuximab, by Merck Group (1 mentions)

Spelling variants of this product

CXCL12 (134 citations) SDF-1α (85 citations) SDF-1α/CXCL12 (9 citations) Recombinant CXCL12 (7 citations) Recombinant SDF-1α (4 citations) Recombinant human SDF-1α/CXCL12 (4 citations) Recombinant murine SDF-1α (CXCL12) (4 citations)

2 protocols using recombinant cxcl12 sdf 1α

Signaling Pathways in Metastatic Regulation

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Recombinant (CXCL12) SDF-1α was purchased from Pepro Tech (USA). The CXCR4 antagonist AMD3100, PHA-665752 and Nystatin were obtained from Sigma (St. Louis, MO). Stattic was obtained from Selleck. Anti-CXCR4 antibodies were obtained from ABCAM. Anti–E-cadherin, anti-Vimentin, anti-ZEB1, anti-STAT3, anti–phosphor-STAT3, and antibodies to c-MET and phospho-c-MET (Tyr1234/1235) were purchased from Cell Signaling Technology (Beverly, MA). Anti-Snail and anti-Twist2 were purchased from Abcam (Cambridge, MA). Anti–Cav-1 and anti–phospho-Cav-1-1 (Tyr14) antibodies were obtained from BD Technology Co. (USA). All the other antibodies were purchased from Santa Cruz Biotechnology (USA).

Cheng Y., Song Y., Qu J., Che X., Song N., Fan Y., Wen T., Xu L., Gong J., Wang X., Zhang C., Qu X, & Liu Y. (2018). The Chemokine Receptor CXCR4 and c-MET Cooperatively Promote Epithelial-Mesenchymal Transition in Gastric Cancer Cells. Translational Oncology, 11(2), 487-497.

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CXCL12/CXCR4 Axis Modulation Protocol

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Recombinant (CXCL12) SDF-1α was purchased from Pepro Tech (USA). The CXCR4 antagonist AMD3100 and NF-κB pathway inhibitor BAY117082 were obtained from Sigma (St. Louis, MO, USA), C225 (cetuximab) was obtained from Merck KGaA (Darmstadt, Germany). The EGFR antagonist was purchased from Cell Signaling Technology. Rabbit anti-CXCR4 antibodies were obtained from Abcam (Cambridge, UK). All the other antibodies were purchased from Santa Cruz Biotechnology (USA).

Cheng Y., Che X., Zhang S., Guo T., He X., Liu Y, & Qu X. (2020). Positive Cross-Talk Between CXC Chemokine Receptor 4 (CXCR4) and Epidermal Growth Factor Receptor (EGFR) Promotes Gastric Cancer Metastasis via the Nuclear Factor kappa B (NF-κB)-Dependent Pathway. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 26, e925019-1-e925019-11.

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