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Cpg oligodeoxynucleotide cpg odn

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CpG-oligodeoxynucleotide (CpG-ODN) is a synthetic DNA molecule containing unmethylated CpG motifs. It functions as a ligand for Toll-like receptor 9 (TLR9), which is involved in the innate immune response.

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Lab products found in correlation

Ifn γ, by R&D Systems (1 mentions) Tnf α, by R&D Systems (1 mentions) Il 15, by R&D Systems (1 mentions) Lipopolysaccharide lps, by Merck Group (1 mentions) Ps 341, by Selleck Chemicals (1 mentions) Polymyxin b pmb, by Merck Group (1 mentions) Sc 514, by Selleck Chemicals (1 mentions)

Spelling variants of this product

CpG-ODN (52 citations) CpG oligodeoxynucleotides (8 citations) CpG- oligodeoxynucleotides (ODN) (4 citations) CpG oligodeoxynucleotide (ODN) 2006 (3 citations) Murine CpG oligodeoxynucleotide (CpG) TLR9 ligand (ODN 1585; Class A) (3 citations) CpG oligodeoxynucleotides (ODN 2006, (3 citations) CpG oligodeoxynucleotide (ODN) 1826 VacciGrade (2 citations)

2 protocols using cpg oligodeoxynucleotide cpg odn

1

Quantifying Cytokine Secretion in Cultured Splenocytes and B Cells

Cited 1 time
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Direct ELISAs of interleukin (IL)-2, IL-4, IL-6, IL-10, IL-12, IL-15, TNF-α, and IFN-γ (R&D systems) were performed using the supernatants of cultured splenocytes (2×106 cells) and ascites.15 (link) ELISAs of IL-15/IL-15 receptor alpha (IL-15Rα) complex (Invitrogen) and IL-15 were performed using supernatants of cultured B lymphocytes (2×106 cells) with lipopolysaccharide (LPS) (0.5 µg/mL, Sigma-Aldrich) or CpG-oligodeoxynucleotide (CpG-ODN) (1 µg/mL, InvivoGen).
Sun W.Z., Lin H.W., Chen W.Y., Chien C.L., Lai Y.L., Chen J., Chen Y.L, & Cheng W.F. (2023). Dual inhibition of BTLA and PD-1 can enhance therapeutic efficacy of paclitaxel on intraperitoneally disseminated tumors. Journal for Immunotherapy of Cancer, 11(7), e006694.
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2

Adiponectin Regulation in Inflammation

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Recombinant human globular adiponectin (gAd) was purchased from BioVision (USA). A stock solution of gAd was prepared in distilled water containing 50 mg/ml BSA to a concentration of 1 mg/ml and aliquots were stored at −20°C until needed. MG132 was obtained from Calbiochem (Germany). PS-341 and SC-514 were supplied by Selleck Chemicals (USA). Lipopolysaccharide (LPS) and polymyxin B (PMB) were obtained from Sigma-Aldrich (USA). CpG-oligodeoxynucleotide (CpG-ODN) was supplied by InvivoGen (USA). Control and IRAK-1 siRNAs were purchased from Santa Cruz Biotechnology Inc. (USA).
Lee K.H., Jeong J., Woo J., Lee C.H, & Yoo C.G. (2018). Globular Adiponectin Exerts a Pro-Inflammatory Effect via IκB/NF-κB Pathway Activation and Anti-Inflammatory Effect by IRAK-1 Downregulation. Molecules and Cells, 41(8), 762-770.
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