Gctof hrms

Chemicals were obtained commercially and used as received. Nuclear magnetic resonance (NMR) spectra were recorded on a Bruker DPX–400 spectrometer (Bruker Co., Billerica, MA, USA) using tetramethylsilane (TMS) as the internal standard. Electric impact ionization (EI) –Mass spectrum was measured on a gas chromatography time of flight high resolution mass spectrometry (GCTOF-HRMS) (Waters Co, Milford, MA, USA) or GC-MS (Agilent 7890A/5975C, Santa Clara, CA, USA) instrument. All products were isolated via short chromatography on a silica gel (200–300 mesh) column using petroleum ether (60–90 °C), unless otherwise noted. Alcohols and diarylmethanes were of analytical grade quality, purchased from Adamas-beta Pharmaceuticals, Inc. (Shanghai, China) Compounds described in the literature were characterized by ¹H-NMR spectra compared to reported data.

Chemicals were obtained commercially and used as received. Nuclear magnetic resonance (NMR) spectra were recorded on a Bruker DPX–400 spectrometer (Bruker Co., Billerica, MA, USA) using tetramethylsilane (TMS) as the internal standard. Electric impact ionization (EI)–Mass spectrum was measured on a gas chromatography time of flight high resolution mass spectrometry (GCTOF-HRMS) (Waters Co, Milford, MA, USA). or GC-MS (Agilent 7890A/5975C, Santa Clara, CA, USA) instrument. Electrospray ionization (ESI)–Mass spectrum was measured on a matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) (Bruker Co., Bremen, Germany). To all copies of 1H NMR, ¹³C NMR and HRMS spectra, please see Figures S2–S45 in Supplementary Materials. All products were isolated by short chromatography on a silica gel (200–300 mesh) column using petroleum ether (60–90 °C), unless otherwise noted. Arylboronic acids and o-(or m-, or p-)chloromethyl bromobenzene were of analytical grade quality, purchased from Adamas-beta Pharmaceuticals, Inc. (Shanghai, China).