D phe cys tyr d trp arg thr pen thr nh2 ctap

Manufactured by Bio-Techne

Sourced in United States

D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP) is a synthetic peptide compound produced by Bio-Techne. It consists of a sequence of nine amino acids. The core function of this product is as a research tool, without further interpretation of its intended use.

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Lab products found in correlation

Picrotoxin, by Merck Group (1 mentions) Fentanyl citrate, by Merck Group (1 mentions) L glutamic acid, by Bio-Techne (1 mentions) Morphine, by Merck Group (1 mentions) Go6983, by Merck Group (1 mentions) U73122, by Merck Group (1 mentions) Wortmannin, by Merck Group (1 mentions) Cid755673, by Bio-Techne (1 mentions) Damgo, by Bio-Techne (1 mentions) U0126, by InvivoGen (1 mentions) Bay43 9006, by Cayman Chemical (1 mentions) Ly294002, by Merck Group (1 mentions)

3 protocols using d phe cys tyr d trp arg thr pen thr nh2 ctap

Neuromodulation Pharmacology Protocol

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(−)-Morphine sulfate pentahydrate (diluted in saline) and clozapine N-oxide (CNO; diluted in saline with 0.1% DMSO) were provided by the National Institute on Drug Abuse Drug Supply Program. Picrotoxin was purchased from Sigma-Aldrich (catalog #P1675). The somatostatin analog D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP) was purchased from Tocris Bioscience (catalog #1560).

McDevitt D.S., Wade Q.W., McKendrick G.E., Nelsen J., Starostina M., Tran N., Blendy J.A, & Graziane N.M. (2024). The Paraventricular Thalamic Nucleus and Its Projections in Regulating Reward and Context Associations. eNeuro, 11(2), ENEURO.0524-23.2024.

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Opioid Receptor Ligand Analysis

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d-Phe-Cys-Tyr-d-Trp-Arg-Thr-Pen-Thr-NH₂(CTAP) and l-Glutamic acid were from Tocris (Minneapolis, MN, USA).
Fentanyl citrate was from Sigma-Aldrich (St Louis, MO, USA). Naloxone was from
Abcam (Cambridge, MA, USA).

Saunders S.E, & Levitt E.S. (2020). Kölliker-Fuse/Parabrachial complex mu opioid receptors contribute to fentanyl-induced apnea and respiratory rate depression. Respiratory physiology & neurobiology, 275, 103388.

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Pharmacological Modulation of GPCR Signaling

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The MOR selective agonist DAMGO (Tocris Bioscience, Ellisville, MO, USA), The MOR selective antagonist D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP) (Tocris Bioscience), and morphine (Sigma-Aldrich, St. Louis, MO, USA) were suspended in sterile serum-free RPMI-1640 medium, and stored at −80°C prior to use. H-89 (InvivoGen, San Diego, CA, USA), LY294002 (Sigma-Aldrich, St. Louis, MO, USA), Wortmannin (Sigma-Aldrich), U0126 (InvivoGen), CID755673 (Tocris Bioscience), U73122 (Sigma-Aldrich), Bay 43-9006 (Cayman, Ann Arbor, MI, USA), farnesylthiosalicytic acid (FTS) (Cayman), and Go 6983 (Sigma-Aldrich), were suspended in DMSO and stored at −20°C until use.

Chang J.K., Cornwell W.D, & Rogers T.J. (2021). The μ-Opioid Receptor Induces miR-21 Expression and is ERK/PKCμ-Dependent. Journal of neuroimmunology, 356, 577585.

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