Cobas amplicor ct ng pcr test

Manufactured by Roche

Sourced in United States

The Cobas Amplicor CT/NG PCR test is a laboratory diagnostic tool used for the detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections. It utilizes polymerase chain reaction (PCR) technology to amplify and detect the DNA of these organisms in clinical samples.

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Lab products found in correlation

Osom trichomonas test, by Sekisui (4 mentions) Wampole impact rpr test kit, by Abbott (1 mentions) Uni gold hiv, by Trinity Biotech (1 mentions) Serodia tp pa, by Fujirebio (1 mentions)

2 protocols using cobas amplicor ct ng pcr test

STI Screening and Management in Uganda

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Testing for STIs was carried out at baseline and every 12 weeks thereafter for up to 2 years. Cervico-vaginal samples were collected by trained study doctors and tested at the research centre laboratory. Samples were tested for Trichomonas vaginalis (OSOM Trichomonas Test, Sekisui Diagnostics LLC, USA), Chlamydia trachomatis and Neisseria gonorrhoea (Cobas Amplicor CT/NG PCR test, Roche Diagnostic Systems, Branchburg, New Jersey, USA). Those who tested positive for STIs were treated following the Uganda national guidelines for syndromic management of STIs24 and the Centers for Disease Control and Prevention (CDC) treatment guidelines for aetiological diagnoses.25 (link)

Kusemererwa S., Abaasa A., Kabarambi A., Onyango M, & Mugisha J.O. (2021). Assessment of risk compensation following use of the dapivirine vaginal ring in southwestern Uganda. Sexually Transmitted Infections, 98(1), 32-37.

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HIV, Trichomoniasis, and Syphilis Testing

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Serial HIV-antibody rapid tests were done using Alere Determine™ HIV-1/2 (Alere Medical Co Ltd, Matsuhidai, Matsudo-shi, Chiba, Japan), followed by OraQuick-ADVANCE® Rapid HIV-1/2 Test (OraQuick-OraSure Technologies Inc, Pennsylvania, USA) to confirm a positive Determine result, with Uni-Gold™ HIV (Trinity Biotech, Ireland) as the tiebreaker. The tests were run by a laboratory technician. A participant was considered to be HIV positive if 2 antibody rapid tests showed positive results.
Additionally, cervico-vaginal samples were taken and tested for T. vaginalis (OSOM® Trichomonas Test, Sekisui Diagnostics LLC, USA) and C. trachomatis / N. gonorrhoeae (Cobas® Amplicor CT/NG PCR test, Roche Diagnostic Systems, Branchburg, New Jersey, USA), and blood samples were taken for syphilis testing using rapid plasma reagin (RPR)(Wampole® Impact RPR Test Kit, Alere™, Pennsylvania, USA). A positive RPR was confirmed using the Treponema pallidum particle agglutination assay (TPPA) (Serodia TP.PA, Fujirebio Inc, Pennsylvania, USA). A participant was reported to have syphilis if both the RPR and TPPA results were positive. Treatment was provided to those who tested positive for any STI according to the Centers for Disease Control and Prevention (CDC) STD treatment guidelines for 2010.[23 ]

Kusemererwa S., Abaasa A., Onyango M., Nel A.M., Isaacs M, & Asiki G. (2018). CONTRACEPTIVE PREFERENCE AMONG WOMEN AT RISK OF HIV ACQUISITION IN A PREPARATORY SCREENING STUDY FOR A PHASE III MICROBICIDE TRIAL IN SOUTH WESTERN UGANDA. AIDS and behavior, 22(Suppl 1), 131-138.

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