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Moisturemetersc

Manufactured by Delfin Technologies
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Sourced in United States, Finland

The MoistureMeterSC is a device designed to measure the moisture content of various materials. It provides accurate and reliable measurements without subjective interpretation.

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Lab products found in correlation

Vapometer, by Delfin Technologies (4 mentions) Moisturemeterd, by Delfin Technologies (1 mentions) Frosted microscope slides, by Thermo Fisher Scientific (1 mentions) Dpx mounting medium, by Merck Group (1 mentions) Histochoice, by Merck Group (1 mentions) Concentrated hcl, by Merck Group (1 mentions) Phosphate buffered saline tablets ph 7.4, by Merck Group (1 mentions) Palmsens4 potentiostat, by PalmSens (1 mentions)

9 protocols using moisturemetersc

1

Facial Modeling and Wrinkle Analysis

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The BTBP 3D Clarity Pro® Facial Modeling and Analysis System (Brigh-Tex BioPhotonics, San Jose, CA, USA) was utilized to obtain high-resolution facial photographs for all study participants at baseline and at 8, 16, and 24 weeks. Facial wrinkles were analyzed through the BTBP 3D Clarity Pro® Facial Modeling and Analysis System (Brigh-Tex BioPhotonics), which uses an algorithm-based model to measure and calculate the average wrinkle severity based on the depth and width [43 (link)]. Average piment intensity score across the face was also measured utilizing the same image analysis system. The following skin biophysical measures were assessed: hydration (MoistureMeterSC; Delfin Technologies, Stamford, CT, USA) and sebum production in µg/cm2 (Sebumeter® SM 815; Courage and Khazaka, Cologne, Germany). Skin hydration (MoistureMeterSC; Delfin Technologies) and sebum excretion (Sebumeter® SM 815; Courage and Khazaka) were measured utilizing handheld non-invasive devices at the left and right buccal areas at 0, 8, 16, and 24 weeks. All subjects were acclimated to ambient temperature for fifteen minutes in a temperature-controlled room prior to any skin biophysical measurements. Subjects were instructed to refrain from applying topical products prior to study visits.
Rizzo J., Min M., Adnan S., Afzal N., Maloh J., Chambers C.J., Fam V, & Sivamani R.K. (2023). Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial. Nutrients, 15(19), 4113.
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2

Facial Modeling and Wrinkle Analysis

Cited 1 time
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The BTBP 3D Clarity Pro® Facial Modeling and Analysis System (Brigh-Tex BioPhotonics, San Jose, CA, USA) was utilized to obtain high-resolution facial photographs for all study participants at baseline and at 8, 16, and 24 weeks. Facial wrinkles were analyzed through the BTBP 3D Clarity Pro® Facial Modeling and Analysis System (Brigh-Tex BioPhotonics), which uses an algorithm-based model to measure and calculate the average wrinkle severity based on the depth and width [43 (link)]. Average piment intensity score across the face was also measured utilizing the same image analysis system. The following skin biophysical measures were assessed: hydration (MoistureMeterSC; Delfin Technologies, Stamford, CT, USA) and sebum production in µg/cm2 (Sebumeter® SM 815; Courage and Khazaka, Cologne, Germany). Skin hydration (MoistureMeterSC; Delfin Technologies) and sebum excretion (Sebumeter® SM 815; Courage and Khazaka) were measured utilizing handheld non-invasive devices at the left and right buccal areas at 0, 8, 16, and 24 weeks. All subjects were acclimated to ambient temperature for fifteen minutes in a temperature-controlled room prior to any skin biophysical measurements. Subjects were instructed to refrain from applying topical products prior to study visits.
Rizzo J., Min M., Adnan S., Afzal N., Maloh J., Chambers C.J., Fam V, & Sivamani R.K. (2023). Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial. Nutrients, 15(19), 4113.
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3

Stratum Corneum Removal Measurements

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Repeated application and removal adhesive disks (D-Squame; CuDerm; 14-mm diameter, ∼100-µm thickness) several times on the same area of skin gradually removed the SC. Replacement of each disk occurred after five cycles. Measurements after 0, 10, 20, and 35 cycles involved two commercial devices (MoistureMeterSC and MoistureMeterD; Delfin Technologies) and the BLE device.
Kwon K., Wang H., Lim J., Chun K.S., Jang H., Yoo I., Wu D., Chen A.J., Gu C.G., Lipschultz L., Kim J.U., Kim J., Jeong H., Luan H., Park Y., Su C.J., Ishida Y., Madhvapathy S.R., Ikoma A., Kwak J.W., Yang D.S., Banks A., Xu S., Huang Y., Chang J.K, & Rogers J.A. (2021). Wireless, soft electronics for rapid, multisensor measurements of hydration levels in healthy and diseased skin. Proceedings of the National Academy of Sciences of the United States of America, 118(5), e2020398118.
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4

Propionate Cream Alleviates Atopic Dermatitis

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For evaluating the clinical effect of propionate application on AD patients, 11 patients with mild to moderate AD were recruited and enrolled at Huashan Hospital, Fudan University, under clinical trial no. ChiCTR2100043963 registered in Chinese Clinical Trials Registry Platform with approval from Huashan Hospital IRB. Before enrollment, all patients signed informed consent. The enrolled patients were given a cream containing 0.05% propionate or vehicle onto their skin lesions of symmetrical parts. The creams were used twice daily. Clinical characteristics of patients were assessed as described previously (Myles et al., 2018 (link)) by a blinded investigator. SCORAD values were determined under standard approaches (Kunz et al., 1997 (link)). The skin symptom intensity of the treated region was valued by dryness, erythema, edema, oozing, excoriation, and lichenification (score 0–3, respectively). The patients provided subjective values (score 0–10) for regional pruritus. The treated region-specific SCORAD score is the sum of skin symptom intensity values and pruritus scores. TEWL was measured with a VapoMeter (Delfin Technologies), and skin hydration was measured with a MoistureMeter SC (Delfin Technologies). All the tests were carried out in a room with controlled temperature (23 ± 1°C) and relative humidity (50 ± 10%).
Qiu Z., Zhu Z., Liu X., Chen B., Yin H., Gu C., Fang X., Zhu R., Yu T., Mi W., Zhou H., Zhou Y., Yao X, & Li W. (2022). A dysregulated sebum–microbial metabolite–IL-33 axis initiates skin inflammation in atopic dermatitis. The Journal of Experimental Medicine, 219(10), e20212397.
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5

Porcine Skin Barrier Characterization

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The PalmSens4 potentiostat was from PalmSens, The Netherlands. The MoistureMeterSC (stratum corneum moisture measurements) was sourced from Delfin Technologies, Finland. Red Dot 3M Electrodes and the A&D Medical UM‐102B Sphygmomanometer were sourced from Medisave, UK. Microtome blades, frosted microscope slides and 4% Paraformaldehyde (PFA) solution in Phosphate Buffered Saline (PBS) were purchased from Fisher Scientific, UK. Phosphate Buffered Saline tablets (pH 7.4), HistoChoice, concentrated HCl and DPX mounting medium were obtained from Sigma‐Aldrich, UK. The Remington G3 Graphite Razor was from Boots, UK. Haematoxylin (modified Mayer's solution), Bluing reagent and Eosin Y solution were from Abcam, UK. The porcine skin was sourced from a local abattoir, UK.
Owen E.J., Hathaway H., Lafferty B, & Jenkins A.T. (2023). Using electrocardiogram electrodes to monitor skin impedance spectroscopic response when skin is subjected to sustained static pressure. Skin Health and Disease, 3(4), e225.
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6

Eczema and Gut Health Impacts of SIM03

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All children were evaluated at baseline and clinical demographics including weight and standing height were documented. Parents were given a study diary to record eczema and gastrointestinal symptoms and intake of study product. Subjects were then reviewed for study outcomes and treatment adherence at one, two and three months after starting SIM03. Eczema outcomes included (a) disease severity by SCORing Atopic Dermatitis (SCORAD) that measured both objective and subjective features of eczema15 ; (b) disease-specific quality of life (QoL) in the preceding week by Children’s Dermatology Life Quality Index (CDLQI) for subjects aged 4–5 years16 (link) and Infants’ Dermatitis Quality of Life Index (IDQOL) for those aged 1–3 years17 (link); and (c) skin biophysical parameters including skin hydration (SH) and transepidermal water loss (TEWL) by MoistureMeterSC and VapoMeter (Delfin Technologies, Kuopio, Finland) respectively according to our published methods18 (link). Parents/carers also recorded daily bowel movements (time, frequency, and stool appearance) and stool consistency using Bristol Stool Scale (BSS)19 (link) and any adverse event.
Chan O.M., Xu W., Cheng N.S., Leung A.S., Ching J.Y., Fong B.L., Cheong P.K., Zhang L., Chan F.K., Ng S.C, & Leung T.F. (2024). A novel infant microbiome formula (SIM03) improved eczema severity and quality of life in preschool children. Scientific Reports, 14, 3168.
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7

Facial Analysis with BTBP 3D Clarity Pro System

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The BTBP 3D Clarity Pro® Facial Modeling and Analysis System (Brigh-Tex BioPhotonics, San Jose, CA, USA) was utilized to obtain high-resolution facial photographs for all study participants at baseline, 8, 16, and 24 weeks (Figure 2). Facial wrinkles were then analyzed through a computer algorithm-based model that incorporates the measurement of the wrinkles’ depth and width. Image analysis was also used to assess the average pigment intensity across the entire face. The following skin biophysical measures were assessed: sebum production (Sebumeter® SM 815; Courage and Khazaka, Cologne, Germany), transepidermal water loss (TEWL) (Vapometer; Delfin Technologies, Stamford, CT, USA), and skin hydration (MoistureMeterSC; Delfin Technologies, Stamford, CT, USA) at baseline, 8, 16, and 24 weeks. Subjects were asked to report any adverse effects throughout the study.
Rybak I., Carrington A.E., Dhaliwal S., Hasan A., Wu H., Burney W., Maloh J, & Sivamani R.K. (2021). Prospective Randomized Controlled Trial on the Effects of Almonds on Facial Wrinkles and Pigmentation. Nutrients, 13(3), 785.
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8

Skin Hydration Measurement Protocol

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Moisture levels of the face and arms were measured using Moisturemeter SC (Delfin Technologies Ltd., Kuopio, Finland) to evaluate the skin surface hydration level. The device detects the tissue dielectric constant (TDC) value using a 1.25 MHz electromagnetic probe to determine conductivity in the epidermal layer, while the dry layer of the stratum corneum acts as an insulator. Average TDC values at baseline and post-supplementation were determined by constantly measuring five different sites on each surface of the face and the arms.
Lin Y.L., Wang C.L., Liu K.L., Yeh C.N, & Chiang T.I. (2022). Omega-3 Fatty Acids Improve Chronic Kidney Disease—Associated Pruritus and Inflammation. Medicina, 58(6), 796.
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9

Skin Barrier Function Assessment

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The investigators assessed skin barrier function by measuring sebum production (Sebumeter SM 815; Courage and Khazaka, Cologne, Germany), transepidermal water loss (TEWL, Vapometer; Delfin Technologies, Stamford, CT, USA), and hydration (MoistureMeterSC; Delfin Technologies, Stamford, CT, USA) at baseline, 4, and 8 weeks.
Rybak I., Haas K.N., Dhaliwal S.K., Burney W.A., Pourang A., Sandhu S.S., Maloh J., Newman J.W., Crawford R, & Sivamani R.K. (2023). Prospective Placebo-Controlled Assessment of Spore-Based Probiotic Supplementation on Sebum Production, Skin Barrier Function, and Acne. Journal of Clinical Medicine, 12(3), 895.
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