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Trans 4 l hydroxyproline

Manufactured by Merck Group
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Trans-4-L-hydroxyproline is a chemical compound used in various laboratory applications. It is a natural amino acid derivative that serves as a key component in the synthesis and analysis of various biomolecules. This product is intended for use in research and development activities within the scientific community.

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Lab products found in correlation

Reagent grade chemicals, by Merck Group (2 mentions) Fluorescein isothiocyanate labelled sinistrin fitc s, by Fresenius (1 mentions)

Spelling variants of this product

Hydroxyproline (55 citations) L-hydroxyproline (17 citations) Trans-4-hydroxyproline (6 citations) 4-hydroxyproline (3 citations) Trans-4-hydroxyproline-l-proline (2 citations)

2 protocols using trans 4 l hydroxyproline

1

Reagent Sourcing for Feeding Studies

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Reagent grade chemicals were obtained from either Sigma-Aldrich Chemicals (St Louis, MO) or Fisher Scientific (Pittsburgh, PA). Trans-4-L-hydroxyproline for feeding studies was purchased from Sigma-Aldrich.
Buchalski B., Wood K.D., Challa A., Fargue S., Holmes R.P., Lowther W.T, & Knight J. (2019). The Effects of the Inactivation of Hydroxyproline Dehydrogenase on Urinary Oxalate and Glycolate Excretion in Mouse Models of Primary Hyperoxaluria. Biochimica et biophysica acta. Molecular basis of disease, 1866(3), 165633.
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2

Synthesis and Labeling of Hydroxyproline Compounds

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Reagent grade chemicals were obtained from either Sigma-Aldrich Chemicals (St Louis, MO) or Fisher Scientific (Pittsburgh, PA). Trans-4-L-hydroxyproline for feeding studies was purchased from Sigma-Aldrich. The synthesis of 13C5-Hyp has been previously described [13 ]. DL-4-Hydroxy-2-ketoglutaric acid lithium salt (HOG) was purchased from Sigma-Aldrich. Fluorescein-isothiocyanate-labelled sinistrin (FITC-S) was purchased from Fresenius Kabi Austria GmbH, Graz, Austria.
Li X., Knight J., Lowther W.T, & Holmes R.P. (2015). Hydroxyproline metabolism in a mouse model of Primary Hyperoxaluria Type 3. Biochimica et biophysica acta, 1852(12), 2700-2705.
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