DSC-60 Plus instrument (Shimadzu, Kyoto, Japan) was utilized to analyze the thermal profile for the pure powder of PNZ, the brand product of PNZ, and the generic product of PNZ. a precise amount of 3-5 mg powder was weighed and transferred into sample pans for each product. The analysis was conducted under controlled conditions, where the samples were scanned over a temperature range of 25-350°C at a rate of 10°C per min while being exposed to a continuous flow of nitrogen at a rate of 100 mL/min. The resulting data was collected and processed using the Lab Solutions TA software. To ensure the statistical significance of the results, the experiment was repeated six times for each product, resulting in a total of six samples (n=6).
Arafat M., Sakkal M., Bostanudin M.F., Alhanbali O.A., Yuvaraju P., Beiram R., Sadek B., Akour A, & AbuRuz S. (2023). Enteric-coating film effect on the delayed drug release of pantoprazole gastro-resistant generic tablets. F1000Research, 12, 1325.