Log In Sign up
The largest database of trusted experimental protocols

Bethanechol chloride

Manufactured by Selleck Chemicals
Visit Supplier

Bethanechol chloride is a chemical compound used in the manufacturing of various pharmaceutical and laboratory products. It is a synthetic cholinergic agent, primarily utilized as a research tool in the study of muscarinic acetylcholine receptor function. The core function of bethanechol chloride is to mimic the effects of the neurotransmitter acetylcholine, which plays a crucial role in the regulation of various physiological processes.

Automatically generated - may contain errors

Lab products found in correlation

Acetyl beta methacholine chloride, by Merck Group (1 mentions) Ketamine, by Henry Schein (1 mentions) Xylazine, by Henry Schein (1 mentions)

2 protocols using bethanechol chloride

1

Flexivent Reagent Preparation

Check if the same lab product or an alternative is used in the 5 most similar protocols
Bethanechol chloride (Selleckchem) was dissolved in 0.9% saline. Acetyl-beta-methacholine-chloride (Sigma) was dissolved in 0.9% saline for flexiVent studies.
Reznikov L.R., Meyerholz D.K., Kuan S.P., Guevara M.V., Atanasova K.R, & Abou Alaiwa M.H. (2018). Solitary cholinergic stimulation induces airway hyperreactivity and transcription of distinct pro-inflammatory pathways. Lung, 196(2), 219-229.
+ Open protocol
+ Expand
2

Bethanechol-Induced Airway Resistance in Piglets

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
After acclimation, piglets were anesthetized with 20mg/kg ketamine and 2.0mg/kg xylazine (Henry Schein Animal Health). Airways were accessed with a laryngoscope. A laryngotracheal atomizer (MADgic) was passed directly beyond the vocal folds to aerosolize either a 500 µl of 0.9% saline control or 8 mg/ml bethanechol chloride (Selleckchem) in 0.9% saline solution to the airway. The dose selected has previously been shown to acutely increase airway resistance in piglets [9 (link)]. Of the total 16 piglets that underwent instillation, 6 piglets were simply observed and euthanized. Histological specimens were examined from these piglets to evaluate overall tolerability of the bethanechol paradigm.
Reznikov L.R., Meyerholz D.K., Kuan S.P., Guevara M.V., Atanasova K.R, & Abou Alaiwa M.H. (2018). Solitary cholinergic stimulation induces airway hyperreactivity and transcription of distinct pro-inflammatory pathways. Lung, 196(2), 219-229.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!