Mouse inflammation cytokine kit

Manufactured by BD

Sourced in United States

The mouse inflammation cytokine kit is a laboratory tool designed to detect and quantify the levels of specific cytokines involved in the inflammatory response in mouse samples. It provides a reliable and standardized method for researchers to analyze the inflammatory profile of their mouse models or experiments.

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Mouse Inflammation Kit (52 citations)

4 protocols using mouse inflammation cytokine kit

Multiplex Cytokine Profiling in Mice

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Serum and peritoneal lavage from animals were used for cytokine dosing by flow cytometry. The cytometric bead array (CBA) technique was used for the quantification of TNF-α, MCP-1, IL-6, IL-10, IL-12, and IFN-γ [40 (link)], using a mouse inflammation cytokine kit (Becton Dickinson Biosciences, San Jose, CA, EUA).

Dutra I.L., Araújo L.G., Assunção R.G., Lima Y.A., Nascimento J.R., Vale A.A., Alves P.C., Trovão L.O., Santos A.C., Silva R.M., Silva L.A., Maciel M.C., de Sousa E.M., Elias W.P., Nascimento F.R, & Abreu A.G. (2020). Pic-Producing Escherichia coli Induces High Production of Proinflammatory Mediators by the Host Leading to Death by Sepsis. International Journal of Molecular Sciences, 21(6), 2068.

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Quantification of Mouse Inflammation Cytokines

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The cytometric bead array (CBA) technique was used for the quantification of TNF-α, MCP-1, IL-6, IL-10, IL-12, and IFN-γ in serum, as described by Maciel et al. (17 (link)), using the mouse inflammation cytokine kit (Becton Dickinson Biosciences, San Jose, CA, EUA).

Braga Filho J.A., Abreu A.G., Rios C.E., Trovão L.O., Silva D.L., Cysne D.N., Nascimento J.R., Fortes T.S., Silva L.A., Guerra R.N., Maciel M.C., Serezani C.H, & Nascimento F.R. (2018). Prophylactic Treatment With Simvastatin Modulates the Immune Response and Increases Animal Survival Following Lethal Sepsis Infection. Frontiers in Immunology, 9, 2137.

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Cytometric Bead Array for Murine Cytokines

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The cytometric bead array (CBA) technique was used for the quantification of TNF-α, MCP-1, IL-6, IL-10, IL-12 and IFN-γ in serum, as described by Maciel et al. (2014) (link), using the Mouse inflammation cytokine kit (Becton Dickinson Biosciences, San Jose, CA, EUA).

Rios C.E., Abreu A.G., Braga Filho J.A., Nascimento J.R., Guerra R.N., Amaral F.M., Maciel M.C, & Nascimento F.R. (2017). Chenopodium ambrosioides L. Improves Phagocytic Activity and Decreases Bacterial Growth and the Systemic Inflammatory Response in Sepsis Induced by Cecal Ligation and Puncture. Frontiers in Microbiology, 8, 148.

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Cytokine Profiling in Murine Inflammation

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Dosage of MCP-1, IFN-γ, TNF-α, IL-12, IL-10, and IL-6 in serum and peritoneal lavage from animals was performed by flow cytometry, using the Mouse Inflammation Cytokine kit (Becton Dickinson Biosciences, San Jose, CA, USA), according to manufacturer’s instructions.

Figueiredo I.F., Araújo L.G., Assunção R.G., Dutra I.L., Nascimento J.R., Rego F.S., Rolim C.S., Alves L.S., Frazão M.A., Cadete S.F., da Silva L.C., de Sá J.C., de Sousa E.M., Elias W.P., Nascimento F.R, & Abreu A.G. (2022). Cinnamaldehyde Increases the Survival of Mice Submitted to Sepsis Induced by Extraintestinal Pathogenic Escherichia coli. Antibiotics, 11(3), 364.

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