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Bis 2

Manufactured by R&D Systems
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Bis II is a laboratory equipment used for the measurement and analysis of various biomolecules. It functions as a spectrophotometer, enabling the quantification and characterization of proteins, nucleic acids, and other biological compounds.

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Lab products found in correlation

Thapsigargin, by R&D Systems (2 mentions) Picrotoxin, by R&D Systems (2 mentions) Chelerythrine, by R&D Systems (2 mentions) Heparin, by R&D Systems (2 mentions) U73122, by R&D Systems (2 mentions) U73343, by R&D Systems (2 mentions) Ml 133, by R&D Systems (2 mentions) Tertiapin lq, by R&D Systems (2 mentions) Bapta, by R&D Systems (2 mentions) Kynurenic acid, by R&D Systems (2 mentions) Tertiapin q, by R&D Systems (2 mentions) Gdp β s, by R&D Systems (1 mentions) Ml 297, by R&D Systems (1 mentions) Phorbol myristate acetate (pma), by R&D Systems (1 mentions)

2 protocols using bis 2

1

Neuronal Activity Modulation Protocols

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The following chemicals were products of R&D Systems: [Thr4,Gly7]-oxytocin (TGOT), kynurenic acid, picrotoxin, GDP-β-S, U73122, U73343, heparin, thapsigargin, BAPTA, chelerythrine, bisindolylmaleimide II (Bis II), phorbol 12-myristate 13-acetate (PMA), tetrodotoxin (TTX), ML 133, ML 297, tertiapin-Q and tertiapin-LQ. Drugs were initially prepared in stock solution, aliquoted and stored at −20°C. For those chemicals which are only soluble in dimethyl sulfoxide (DMSO), the concentration of DMSO was less than 0.1%. This concentration of DMSO either in the recording pipettes or in the bath had no significant effects on neuronal activity.
Hu B., Boyle C.A, & Lei S. (2020). Oxytocin Receptors Excite Lateral Nucleus of Central Amygdala by PLCβ and PKC-dependent Depression of Inwardly Rectifying K+ Channels. The Journal of physiology, 598(16), 3501-3520.
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2

Purchasing and Preparation of Research Chemicals

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The following chemicals were purchased from R&D Systems: NMB, kynurenic acid, picrotoxin, U73122, U73343, heparin, thapsigargin, BAPTA, chelerythrine, bisindolylmaleimide II (Bis II), phorbol 12-myristate 13-acetate (PMA), TTX, ML 133, tertiapin-Q (TQ), tertiapin-LQ, BIM23042, and PD168368. Stock solutions of drugs were prepared and aliquoted for storage at −20°C until use. For chemicals dissolved in dimethyl sulfoxide (DMSO), the final concentration of DMSO was less than 0.1%.
Boyle C.A, & Lei S. (2023). Neuromedin B Excites Central Lateral Amygdala Neurons and Reduces Cardiovascular Output and Fear-Potentiated Startle. Journal of cellular physiology, 238(6), 1381-1404.
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