N bromosuccinimide

Manufactured by Merck Group

Sourced in United States, Germany, United Kingdom

N-bromosuccinimide is a chemical compound used as a laboratory reagent. It is a source of electrophilic bromine and is commonly utilized in organic synthesis reactions, such as bromination and substitution reactions.

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Lab products found in correlation

Dichloromethane, by Merck Group (5 mentions) Tetrahydrofuran, by Merck Group (5 mentions) N n dimethylformamide (dmf), by Merck Group (5 mentions) Acetonitrile, by Merck Group (5 mentions) Methanol, by Merck Group (5 mentions) Triethylamine, by Merck Group (4 mentions) Fetal bovine serum (fbs), by Thermo Fisher Scientific (4 mentions) Toluene, by Merck Group (4 mentions) Acetic acid, by Merck Group (4 mentions) Ethyl acetate, by Merck Group (4 mentions) Sodium thiosulfate, by Merck Group (3 mentions) Diethyl phosphite, by Merck Group (3 mentions) Dulbecco phosphate buffered saline (dpbs), by Thermo Fisher Scientific (3 mentions) Trypsin edta, by Thermo Fisher Scientific (3 mentions) Methyl 3 5 dimethylbenzoiate, by Merck Group (3 mentions) Anti gst tb, by PerkinElmer (3 mentions) Streptavidin d2, by PerkinElmer (3 mentions) Luc hek293 cell line, by BPS Biosciences (3 mentions) Cell culture media, by Thermo Fisher Scientific (3 mentions) One step luciferase assay system, by BPS Biosciences (3 mentions)

Close spelling variants of this product

N-bromosuccinimide (NBS,

41 protocols using n bromosuccinimide

Electrochemical Synthesis of Gold Nanorods

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All reagents were used without further purification. Epinephrine (EPI), dopamine, hydroquinone (HQ), hexaamin ruthenium (III), tartaric acid, sodium metabisulphite, potassium chloride, sodium chloride and N-methyl pyrrolidone (NMP) were purchased from Sigma-Aldrich. As supporting electrolyte, 0.1 M buffer solutions were prepared from ortho-phosphoric or acetic acid in the pH range of 3.0–9.0. For the solution-based synthesis of GNRs, phenanthrene-9,10-quinone, 1,3-diphenylacetone, N-bromosuccinimide (NBS), diphenylacetylene, bis(1,5-cyclooctadiene)nickel(0) (Ni (COD)₂) and iron trichloride were purchased from Sigma-Aldrich.

Sainz R., del Pozo M., Vilas-Varela M., Castro-Esteban J., Pérez Corral M., Vázquez L., Blanco E., Peña D., Martín-Gago J.A., Ellis G.J., Petit-Domínguez M.D., Quintana C, & Casero E. (2020). Chemically synthesized chevron-like graphene nanoribbons for electrochemical sensors development: determination of epinephrine. Scientific Reports, 10, 14614.

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Synthesis and Characterization of Polymer Electrolytes

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All chemicals, if not specified otherwise, were used as received without further purification. Poly (2,6-dimethyl-1,4-phenyleneoxide) (PPO) (M_n = 20,000, Đ = 2.5) was purchased from Polysciences Inc. and dried under vacuum at 60 °C overnight before use. M ethanol (99.9%), ethanol (99.9%) and chloroform (99.8%) were purchased from Fisher Scientific. N-Bromosuccinimide (NBS) (99%), 2,2′-azobis(2-methylpropionitrile) (AIBN) (98%), tetrahydrofuran (THF, ACS, >99%), diethyl ether (>99%), chloroform-d (CDCl₃-d, 99.9% D), Irgacure^® 2959, D₂O (99.9% D) and 1,2-dichloroethane (99.8%) were purchased from Sigma-Aldrich (Merck KGaA, Darmstadt, Germany). Dimethyl sulfoxide-d₆ (DMSO-d₆, 99.9%), N-methyl-2-pyrrolidone (NMP, reagent grade) were supplied from Acros Organics. Chlorobenzene (ACS reagent, ≥99.5%), diallymethylamine (97%) and piperidine (≥99%) were bought from ABCR GmbH. Allyl bromide (98%) and allyl chloride (98%) were bought from Alfa Aesar. The electrolytes MV and TMA-TEMPO were provided by JenaBatteries GmbH (Jena, Germany). FAA-3-50^® was purchased from Fumatech BWT GmbH (Bietigheim-Bissingen, Germany).

Tsehaye M.T., Yang X., Janoschka T., Hager M.D., Schubert U.S., Alloin F, & Iojoiu C. (2021). Study of Anion Exchange Membrane Properties Incorporating N-spirocyclic Quaternary Ammonium Cations and Aqueous Organic Redox Flow Battery Performance. Membranes, 11(5), 367.

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Functionalized Polymeric Biomaterials Synthesis

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L-lactide was graciously donated by Altasorb^® and recrystallized in ethyl acetate before use. PLLA (Resomer L207S) with an inherent viscosity of 1.6 dl/g was purchased from Boehringer Ingelheim (Ingelheim, Germany). Heparin was purchased from Fisher Scientific and modified with L-cysteine. Polyethylene glycol modified at one end with thiol (PEG-SH) of a MW of 10 kDa was purchased from Layson Bio. Polycaprolactone (PCL) with a molecular weight of 70–80 kDa, N-Bromosuccinimide (NBS), triethylamine (TEA), Luperox^® A98 benzoyl peroxide, benzene, mineral oil, Span 80^®, ethyl acetate, hexane, benzyl alcohol, magnesium sulfate (MgSO₄), sodium thiosulfate, triazabicyclodecene (TBD), L-cysteine, fructose, tetrahydrofuran (THF) and dichloromethane (DCM) were purchased from Sigma-Aldrich Company (USA) and used as received.

Navarro R.S., Jiang L., Ouyang Y., Luo J., Liu Z., Yang Y., Qiu P., Kuroda K., Chen Y.E., Ma P.X, & Yang B. (2021). Biomimetic Tubular Scaffold with Heparin Conjugation for Rapid Degradation in in situ Regeneration of a Small Diameter Neoartery. Biomaterials, 274, 120874.

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Reagents and Materials for Peptide Synthesis

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Example 1

Reagents for peptide synthesis were purchased from Chem-Impex (Wood Dale, Ill.), NovaBiochem (La Jolla, Calif.), or Anaspec (San Jose, Calif.). Rink amide resin LS (100-200 mesh, 0.2 mmol/g) was purchased from Advanced ChemTech. Cell culture media, fetal bovine serum, penicillin-streptomycin, 0.25% trypsin-EDTA, and DPBS were purchased from Invitrogen (Carlsbad, Calif.). Methyl 3,5-dimethylbenzoiate, N-bromosuccinimide, diethyl phosphite, 2,2′-dipyridyl disulfide, and other organic reagents/solvents were purchased from Sigma-Aldrich (St. Louis, Mo.). Anti-GST-Tb and streptavidin-d2 were purchased from Cisbio (Bedford, Mass.). The NF-κB reporter (Luc)-HEK293 cell line and One-Step™ luciferase assay system were purchased from BPS Bioscience (San Diego, Calif.).

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US11266713B2. Di-sulfide containing cell penetrating peptides and methods of making and using thereof (2022-03-08). Ohio State Innovation Foundation [US]. Inventors: Dehua Pei [US], Ziqing Qian [US].

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Reagents and Materials for Peptide Synthesis

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Example 1

[Figure (not displayed)]

US11351222B2. Di-sulfide containing cell penetrating peptides and methods of making and using thereof (2022-06-07). Ohio State Innovation Foundation [US]. Inventors: Dehua Pei [US], Ziqing Qian [US].

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Synthesis of 2-Amino-6-chloropurine Derivative

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2-Amino-6-chloropurine,
2-bromoethoxy-tert-butyldimethylsilane, N-bromosuccinimide
(NBS), sodium acetate (AcONa), glacial acetic acid (AcOH), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide
(EDC), 4-dimethylaminopyridine (DMAP), 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethylaminium
tetrafluoroborate (TBTU), sodium hydride (NaH), and sulfuric acid
were purchased from Sigma-Aldrich. Methanol (MeOH), dimethylformamide
(DMF), and acetonitrile (MeCN) were purchased from Scharlab.

Rodríguez-Muñiz G.M., Fraga-Timiraos A.B., Navarrete-Miguel M., Borrego-Sánchez A., Roca-Sanjuán D., Miranda M.A, & Lhiaubet-Vallet V. (2023). Reductive Photocycloreversion of Cyclobutane Dimers Triggered by Guanines. The Journal of Organic Chemistry, 88(14), 10111-10121.

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Synthesis and Characterization of Targeted Liposomes

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OVA (Grade VII, catalog number A7641, purity > 99%), calcein, 1-ethyl-3-(dimethylaminopropyl)-carbodiimide hydrochloride (EDC), p-aminophenyl α-dextro (d)-mannopyranoside, cholesterol (Chol), N-bromosuccinimide, TNBS, and phenylglyoxal, were purchased from Sigma-Aldrich Inc. (St. Louis, MO, USA), and 10,12-tricosadiynoic acid was obtained from Fluka (Buchs, Switzerland). EYPC, EYSM, PBPS, and EYPE were purchased from Avanti Lipids Polar Inc., and FPE was the product of Molecular Probes (Eugene, OR, USA). Sepharose 6B and PD-10 column were obtained from General Electric (GH) Healthcare Bio-Sciences Corp. (Piscataway, NJ, USA). Unless otherwise specified, all other reagents were of an analytical grade.

Tang C.C., Shi Y.J., Chen Y.J, & Chang L.S. (2017). Ovalbumin with Glycated Carboxyl Groups Shows Membrane-Damaging Activity. International Journal of Molecular Sciences, 18(3), 520.

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Synthesis of Conjugated Benzothiazole Derivative

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2,5-Bis(tributylstannyl)thiophene (97%), tetrakis(triphenylphosp-hine) palladium(0) (Pd(PPh₃)₄, 99%), n-bromosuccinimide (NBS, 99%), tetrahydrofuran (anhydrous, 99.9%), toluene (anhydrous, 99.8%) were purchased from Sigma-Aldrich company. 4,7-Dibromo-2,1,3-benzothiadiazole (98%), 4-hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene (98%) were purchased from TCI company. All chemicals were used without further purification. 4,7-Bis(4-hexylthiophen-2-yl)benzo[c][1,2,5]thiazole (1) was prepared according to a previously published procedure.³⁵

Trinh C.K., Oh H.S, & Lee H. (2023). The solvent effect on the morphology and molecular ordering of benzothiadiazole-based small molecule for inkjet-printed thin-film transistors. RSC Advances, 13(21), 14210-14216.

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Synthesis and Characterization of Anion Exchange Membranes

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ZnCl₂, SnCl₄, CMME, benzoyl peroxide (BPO), azobisisobutyronitrile (AIBN), N-bromosuccinimide (NBS), 1,1,2,2-tetrachloroethane (TCE), CDCl₃, polysulfone (PSU) random copolymer (average M_n ∼ 22 000), bis(4-fluorophenyl) sulfone (DFDPS), 4,4′-(hexafluoroisopropylidene)diphenol (6F-BPA), 4,4′-dihydroxybiphenyl (BP), methyl iodide, Cs₂CO₃, K₂CO₃, CaCO₃, deuterated chloroform (CDCl₃) and N,N-dimethylsulfoxide (DMSO-d₆), 1-methyl-2-pyrrolidinone (NMP), and N,N-dimethylacetamide (DMAc) were purchased from Sigma-Aldrich. Sodium chloride (NaCl), methanol and hydrochloric acid were supplied by Samchun Chemicals and used as received. Tetra(trimethylaminemethylene)-4,4′-dihydroxydiphenylether (TADHDPE) was synthesized following our previous report.^{27 (link)} The FAA-3-30 membrane was purchased from FUMATECH as a reference AEM, and prior to its use, the counter ion was converted to chloride anion using aqueous 1 M NaCl solution.

Shin D., Nugraha A.F., Wijaya F., Lee S., Kim E., Choi J., Kim H.J, & Bae B. (2019). Synthetic approaches for advanced multi-block anion exchange membranes. RSC Advances, 9(37), 21106-21115.

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Synthesis and Characterization of BODIPY Dyes

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4-Acetamidobenzaldehyde, 4-bromobenzaldehyde, N-bromosuccinimide (NBS), boron trifluoride diethyl etherate (BF₃·OEt₂), 2,4-dimethylpyrrole, glacial acetic acid, piperidine, Rhodamine 6G, anhydrous sodium sulfate (Na₂SO₄), tetrachloro-1,4-benzoquinone (p-chloranil), triethylamine (TEA), trifluoroacetic acid (TFA), and zinc phthalocyanine were purchased from Sigma-Aldrich. Spectroscopic grade solvents were used for the photophysical and the open aperture Z-scan studies.

Ngoy B.P., May A.K., Mack J, & Nyokong T. (2019). Optical Limiting and Femtosecond Pump-Probe Transient Absorbance Properties of a 3,5-distyrylBODIPY Dye. Frontiers in Chemistry, 7, 740.

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