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Ge explore locus sp micro ct scanner

Manufactured by GE Healthcare
Sourced in United States

The GE eXplore Locus SP Micro-CT Scanner is a compact, high-resolution imaging system designed for preclinical research applications. The scanner utilizes X-ray computed tomography (CT) technology to capture detailed 3D images of small animal specimens or other small-scale samples. The system provides non-invasive, high-contrast imaging capabilities to support a variety of research objectives.

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2 protocols using ge explore locus sp micro ct scanner

1

Micro-CT Analysis of Tibial Bone Morphometry

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Tibias were fixed in 10% buffered formalin at 4°C overnight and stored in 70% ethanol at 4°C until use. For analyses, tibias were embedded in methylmethacrylate and then scanned with a GE eXplore Locus SP Micro-CT Scanner (GE Healthcare, Pittsburgh, PA, USA) using a 12-μm voxel protocol and the following scan parameters: 80 kV, 80 μA, and 2960 ms exposure time. Bone density was normalized with an acrylic calibration phantom that included densities equivalent to air, water, and bone. Image reconstructions and analyses were performed with Microview and an Advanced Bone Application database (version 2.3; GE Healthcare). Mineralized tissue was segregated from air or soft tissue, based on a threshold of 1758 HU [corresponding to BMD = 300 mg hydroxyapatite acid/cm3]. Trabecular morphometry was characterized by measuring the fraction of bone volume/total volume (BV/TV), the trabecular thickness (Tb.Th), the trabecular number (Tb.N), and the trabecular separation (Tb.Sp).
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2

Maxillary Molar Extraction Socket Analysis

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The maxillary alveolar bone was fixed in 4% paraformaldehyde for 48 hours, and then transferred to 70% alcohol at 4°C until use. The interradicular bone of the maxillary M1s was scanned and analysed. The extraction sockets were scanned using a GE eXplore Locus SP Micro‐CT Scanner (GE Healthcare). Image reconstructions and analyses of the mesial roots of the maxillary first molar extraction sockets were segmented by semi‐manual contouring and analysed using Microview and an Advanced Bone Application database (version 2.3; GE Healthcare). Trabecular parameters were identified by the direct‐measures technique.
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