Biograph 64 truepoint pet ct scanner

A three-dimensional mode was used for PET/CT examinations performed on a Biograph 64 TruePoint PET/CT scanner (Siemens Medical Solutions, Knoxville, TN), 30 min after the co-injection of ⁶⁸Ga/²¹³Bi –DOTA-SP. Five minutes acquisition time was used for PET of brain and 2 min acquisition per bed position for body (from the neck to the upper thighs).
The PET image data were corrected for scatter and attenuation using the CT data and reconstructed in a 168 × 168 matrix. The reconstruction was performed using the TrueX algorithm (Siemens Medical Solutions) with PSF, three iterations, 21 subsets, and no post filtering.
The PET/CT images (half-body-attenuated and non-attenuated PET, CT, and fused images) were transferred to a multimodal work station (MMWS; Syngo TrueD; Siemens Medical Solutions) for analysis.

A commercially available ¹⁸F-DOPA was used (IASOdopa®, IASON GmbH). A Biograph 64 TruePoint PET/CT scanner (Siemens Healthineers) was used for whole-body PET/CT imaging in three-dimensional mode (3 min per bed position). Patients were asked to empty their bladder prior to the examination. Furosemide (20 mg) and ¹⁸F-DOPA (median 255 MBq, range 236–272 MBq) were consecutively administered intravenously and positron emission scans were initiated approximately 60 min after injection. A diagnostic CT scan covering the neck, chest, abdomen, and pelvis was acquired with automatic exposure control using tube current modulation (CARE Dose 4D; Siemens Healthineers; scan parameters: 120 kV, 100–190 mAs, collimation 2 × 5 mm, pitch 1.5) in portal venous phase (individually calculated according to the formula: Delay [s] = (VolumeContrast Agent [mL] + Volume Saline [mL])/2.5 mL/s) with automated intravenous injection [2.5 mL/s] of an iodine-based contrast agent (Ultravist 300™; Bayer Healthcare; 1.5 mL/kg body weight) and a saline chaser of 100 mL. CT datasets were used for PET attenuation correction.