Somatom definition ct scanner

Manufactured by Siemens

Sourced in Germany

The Somatom Definition CT scanner is a computed tomography (CT) imaging device manufactured by Siemens. It is designed to capture high-quality, three-dimensional images of the human body for medical diagnosis and analysis purposes.

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Lab products found in correlation

Ge lunar idxa, by GE Healthcare (1 mentions) Lightspeed qxi ct scanner, by GE Healthcare (1 mentions) Achieva dstream, by Philips (1 mentions) Tim symphony, by Siemens (1 mentions) Symbia s, by Siemens (1 mentions) Biograph mct pet ct system, by Siemens (1 mentions)

10 protocols using somatom definition ct scanner

Quantitative CT-based Assessment of Hip Bone Density

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CT scans of subjects’ hip joints were performed on a 64-row Siemens Somatom Definition CT scanner (Siemens, Erlangen, Germany) with a Mindways calibrated body model (Mindways Software Inc., Austin, Texas, USA). The acquisition parameters were as follows: 120 kV; 217 mAs; pitch of 1.2; reconstruction slice thickness of 1 mm; reconstruction field of view 50 cm; and medium reconstruction kernel (B40f). The scanning range was 1 cm above the femoral head to 3 cm below the lesser trochanter. The subjects’ knees were flat, and their feet were rotated inwards to reduce overlap between the proximal femur and the acetabulum on the 2D projected image. This study analyzed hip CT scans using the commercial QCTPro (Mindways Inc., Austin, Texas, USA) CTXA module. Three standard DXA hip ROIs were generated, namely, FN, TR, and IT, and DXA equivalent aBMD results of each ROI were obtained. The FN ROI was a narrow frame 10 or 15 mm wide to avoid the overlap between the acetabulum and FN in 2D projection images (Figure 3). In the present study, the World Health Organization (WHO) BMD criteria for osteoporosis were used as follows: osteoporosis was defined by a BMD T-score of -2.5 or less at the FN or total hip; osteopenia was defined by a BMD T-score between -1.0 and -2.5 at the FN or total hip; and normal was defined by a BMD T-score of -1 or more at the FN or total hip.

Li J., Wang Y., Zhang X., Zhang P., Su Y., Bai L., Wang Y., Wang M, & Zhao J. (2022). Associations of muscle size and fatty infiltration with bone mineral density of the proximal femur bone. Frontiers in Endocrinology, 13, 990487.

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Quantitative CT Analysis of Cadaveric Femora

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Forty-four fresh frozen, transplant grade cadaveric femora were obtained from 44 individual donors (Table 1). The specimens were selected from a larger cohort of 100 cadaveric specimens based on femoral neck areal bone mineral density (aBMD) T-score (GE Lunar iDXA, GE Healthcare Inc., Madison, WI) such that the sample uniformly covered the range from osteoporotic to normal. All specimens were thawed to room temperature and scanned in air for maximum contrast using a Siemens Somatom Definition CT scanner (Siemens Healthcare, Forchheim, Germany). Each femur was scanned twice in the same position using two distinct QCT protocols for model comparison (Fig. 1).
A QCT scanning phantom (Mindways Inc., Austin, TX, USA) was placed in the field of view to convert Hounsfield units (HU) to equivalent K₂HPO₄ density, assumed to be equal to bone ash density (Cong et al. 2011 (link)):

ρ_{ash} = ρ_{K_{2} HP O_{4}} = - 9 \cdot 10^{- 3} + 7 \cdot 10^{- 4} HU

Dragomir-Daescu D., Salas C., Uthamaraj S, & Rossman T. (2014). Quantitative computed tomography-based finite element analysis predictions of femoral strength and stiffness depend on computed tomography settings. Journal of biomechanics, 48(1), 153-161.

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Helical TomoTherapy for Locally Advanced Lung Cancer

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Seventeen patients with non-small cell lung cancer who previously underwent Helical TomoTherapy (HT) at Nanjing Drum Tower Hospital were selected. Pretreatment 4DCT data were obtained for all patients to determine the internal margin of the clinical. Patient characteristics are summarized in Table 1. Planning CT and 4DCT scans were performed using a Siemens SOMATOM Definition CT scanner (Siemens, Erlangen, Germany) with a 5 mm slice thickness covering the entire chest. The following standard scan parameters were used: 120 kVp, 120 mA, 0.80.8 pixel spacing.Table 1

Baseline characteristics of 17 patients with locally advanced lung cancer

Characteristic	Value
Sex
Male	14
Female	3
Age (years)
Median (range)	67 (47–89)
Stage
III	5
IV	12
Tumor location
Right upper lobe	5
Right lower lobe	4
Left upper lobe	6
Left lower lobe	2
PTV volume (cm³)
Median (range)	167.8 (38.24–396.89)

Li S., Liu J., Gao S., Yin Y., Zhang L., Han Y., Zhang X., Li Y., Yan J, & Hou Z. (2023). CT ventilation image-guided helical Tomotherapy at sparing functional lungs for locally advanced lung cancer: analysis of dose-function metrics and the impact on pulmonary toxicity. Radiation Oncology (London, England), 18, 6.

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Detailed CT Analysis of Keel Bone Fractures

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CT scanning of 62 keel bones with remaining soft tissues (intact muscles and fasciae) was performed using a Siemens Somatom Definition CT scanner with the following settings: 120 kV, 300 mAs, slice thickness 0.6cm, pitch 0.35 cm, slice increment 0.2 cm and a sharp reconstruction algorithm (H70h). A constant field of view of 17cm was used, resulting in a pixel size of 0.34 cm.
Mimics software, version 18 (Materialise Inc., Leuven, Belgium), was used to visualize the CT images and to generate 3D models of the keen bones. 3D models of the bone were generated using automatic segmentation applying a Hounsfield unit (HU) range from 226 to 3071.
The assessor carrying out both the CT scans, 3D modelling and evaluation of the observations obtained was blinded to any information related to both origin, age, and macroscopic findings. The fractures were assessed both from the CT images and the 3D models. For localization of the fractures the keel was divided into three sections (Fig 2) [29 ]

Thøfner I., Hougen H.P., Villa C., Lynnerup N, & Christensen J.P. (2020). Pathological characterization of keel bone fractures in laying hens does not support external trauma as the underlying cause. PLoS ONE, 15(3), e0229735.

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Pediatric Chest CT with Contrast

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A free breathing contrast-enhanced chest CT scan was acquired within the first year of life using a standardised protocol. The majority of scans (18/21) were acquired on an Emotion 6 CT scanner (Siemens Healthcare), 2/21 were acquired on a SOMATOM Definition CT scanner (Siemens Healthcare), and 1/21 was acquired on a Lightspeed QX/i CT scanner (GE Healthcare). The following range of parameters applies, with differences caused by changes in CT protocols over the years: tube load 20–101 mAs, kilovoltage peak 80–120 kV, field-of-view 103–214 mm, slice thickness 0.75–2.5 mm, kernel B30s–B75f. In 90% of patients, a split bolus contrast enhancement protocol was used with both arterial and venous contrast enhancement.

Elders B.B., Kersten C.M., Hermelijn S.M., Wielopolski P.A., Tiddens H.A., Schnater J.M, & Ciet P. (2023). Congenital lung abnormalities on magnetic resonance imaging: the CLAM study. European Radiology, 33(7), 4767-4779.

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Multimodal Imaging Evaluation of Pediatric Pancreatitis

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Computed tomography (CT) examinations were performed with 3 different CT scanners: a 16-slice GE Optima 540 CT system (General Electric Medical Systems, Milwaukee, Wis, USA), a 16-slice Somatom Emotion CT system (Siemens, Erlangen, Germany), and a 64-slice dual-source Somatom Definition CT scanner (Siemens). Postcontrast abdominal CT images were obtained at the venous phase after intravenous contrast injection.
Magnetic resonance imaging (MRI) examinations were performed with 3 different 1.5 Tesla MR scanners; Philips Achieva dStream (Koninklijke Philips N.V., Nederland), Siemens Symphony TIM (Siemens), and Siemens Aera (Siemens). The routine abdominal MRI protocol for pancreatitis in all scanner consisted of coronal T2-weighted, axial T2-weighted, axial T2-weighted fat-suppressed, dual-echo gradient T1-weighted, 3-dimensional MR cholangiopancreatography (MRCP), diffusion-weighted imaging, pre-contrast interpolated gradient echo T1-weighted and dynamic contrast-enhanced (arterial phase, portal venous phase, and 5-min delayed phase) T1-weighted images. Due to the prominent difference in size of our patient cohort, between 1 and 18 years old, field-of-view was adjusted in each examination according to the patient’s size, ranging from 380-280 to 285-160 mm.

Ayaz E., Özcan H.N., Hızarcıoğlu Gülşen H., Özkale Yavuz Ö., Seber T., Gümüş E., Oğuz B, & Haliloğlu M. (2023). Acute Pancreatitis and Acute Recurrent Pancreatitis in Children: Imaging Findings and Outcomes. Turkish Archives of Pediatrics, 58(1), 89-97.

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Standardized Cranial CT Imaging Protocol

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All NECT images were carried out on SIEMENS SOMATOM definition CT scanner. The
scanning was performed using a standard clinical protocol with an axial
technique of 2.4-mm section thickness and reconstruction interval, and with a
scanning energy of 120 kVp tube voltage. The image matrix size was 512 × 512.
The scan ranged from the skull base to the cranium, with a thickness of 3 mm per
layer.

Liu J., Tao W., Wang Z., Chen X., Wu B, & Liu M. (2021). Radiomics-based prediction of hemorrhage expansion among patients with thrombolysis/thrombectomy related-hemorrhagic transformation using machine learning. Therapeutic Advances in Neurological Disorders, 14, 17562864211060029.

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Comprehensive Hip Joint Imaging Protocol

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With IRB approval (#51053) and informed consent, one male with no history of hip pain or pathology was imaged (32 years old, 177 cm, 73 kg, BMI 23.3). An orthopaedic surgeon performed the three exams (Figure 6). 280 ± 5 frames were collected per exam. Radiation settings were 87 kVp/3.3 mA (fluoro 1) and 88 kVp/3.4 mA (fluoro 2). CT images of the entire pelvis, proximal femur, and knee were acquired with a Siemens SOMATOM Definition CT Scanner (0.7 mm slice thickness, 355 mm FOV, 512 × 512 matrix) and bones were segmented with Amira. Model-based tracking and filtering of results was completed as described above. Outcome measures included joint angles, translations, bone-bone distance, and videos of bone motion.

Kapron A.L., Aoki S.K., Peters C.L., Maas S.A., Bey M.J., Zauel R, & Anderson A.E. (2014). Accuracy and Feasibility of Dual Fluoroscopy and Model-Based Tracking to Quantify In Vivo Hip Kinematics During Clinical Exams. Journal of applied biomechanics, 30(3), 461-470.

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Multimodal Imaging Protocol for Oncology

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Contrast-enhanced full-dose CT from the neck to the pelvis was performed with oral and intravenous contrast material and a slice thickness of 2 mm for the body and 1 mm for the neck on a multislice Somatom Definition CT scanner (at least a 64-slice scanner; Siemens/ CTI). Planar whole-body BS was performed 2.5-4 h after intravenous injection of 500 6 10% MBq of 99m Tc-diphosphonate on a doublehead g-camera (a Symbia S, a T2, or a T16; all Siemens/CTI) equipped with a low-energy, high-resolution collimator. 18 F-FDG PET/CT was performed 1 h after the intravenous administration of a 3 MBq/kg dose of 18 F-FDG from the head to the upper thigh at 1-3 min per bed position on a Biograph mCT PET/CT system (either a 40-or a 64-slice CT scanner) (Siemens/CTI), accredited by European Association of Nuclear Medicine Research Limited. Scan acquisition and reconstructions were performed following the recommendations of the European Association of Nuclear Medicine guideline for oncologic 18 F-FDG PET/CT imaging (20) . Before the PET acquisition, the patients underwent a low-dose CT scan during tidal breathing for attenuation correction (80-140 kVp; quality reference, 30 mAs; pitch, 1).

van Es S.C., Velleman T., Elias S.G., Bensch F., Brouwers A.H., Glaudemans A.W.J.M., Kwee T.C., Iersel M.W., Maduro J.H., Oosting S.F., de Vries E.G.E, & Schröder C.P. (2021). Assessment of Bone Lesions with ¹⁸F-FDG PET Compared with ^99mTc Bone Scintigraphy Leads to Clinically Relevant Differences in Metastatic Breast Cancer Management. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 62(2).

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CT Scanning of Forensic Specimen

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The specimen LP-UFC 722 was scanned using a Siemens Somatom Definition CT scanner, at the Department of Forensic Medicine, University of Copenhagen. After chemical/mechanical preparation, the entire specimen was scanned with the following settings: 140 kV, 550 mAs, 0.6 mm slice thinness, 0.4 pitch, 0.3 slice increment and a sharp reconstruction algorithm (H70h). A field of view of 182 mm was used resulting in images with a pixel size of 0.35 mm.
A detailed scanning of the skull was also performed using the same settings, but reducing the field of view to 93 mm. The resulted pixel size of the CT images was 0.18 mm. The CT scanning data processed using the image software Mimics (Materialise) version 12. A 3D model of the skull was created by using data segmentation methods described by Lynnerup (2007) and Villa & Lynnerup (2012) (link).

Limaverde S., Pêgas R.V., Damasceno R., Villa C., Oliveira G.R., Bonde N, & Leal M.E. (2020). Interpreting character variation in turtles: Araripemys barretoi (Pleurodira: Pelomedusoides) from the Araripe Basin, Early Cretaceous of Northeastern Brazil. PeerJ, 8, e9840.

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