Au400 autoanalyzer

Manufactured by Beckman Coulter

Sourced in United States, Switzerland

The AU400 Autoanalyzer is a clinical chemistry analyzer designed for high-throughput, routine laboratory testing. It is capable of performing a wide range of biochemical assays for the diagnosis and monitoring of various medical conditions.

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Lab products found in correlation

Atrial natriuretic peptide eia kit, by Merck Group (1 mentions) Laquatwin na meter, by Horiba (1 mentions) Bradford assay, by Bio-Rad (1 mentions) Quantichrom urea assay kit, by BioAssay Systems (1 mentions)

Spelling variants of this product

Autoanalyzer (29 citations) AU400 (26 citations)

3 protocols using au400 autoanalyzer

Renal Electrolyte Homeostasis: Comprehensive Analysis

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Serum and 24-h urine samples were analyzed for creatinine by capillary electrophoresis and for Na⁺ concentration using a Beckman AU400 Autoanalyzer at the University of Texas-Southwestern George M. O’Brien Kidney Research Core Center. For hourly urine samples from the acute salt loading study, urinary Na⁺ levels were measured using the LAQUAtwin Na⁺ meter (Horiba Scientific, Minami-ku Kyoto, Japan) following the manufacturer’s protocol. Glomerular filtration rate (GFR) was calculated using the creatinine clearance (ClCr) method. Urine was assessed for blood urea nitrogen (BUN) levels using the QuantiChrom Urea Assay Kit (BioAssay Systems, Hayward, California, USA). Urinary protein concentrations were determined using the Bradford assay (Bio-Rad, Hercules, California, USA) and normalized to creatinine levels. Atrial natriuretic peptide (ANP) levels were measured in the plasma using the Atrial Natriuretic Peptide EIA Kit (Sigma) following the manufacturer’s protocol.

Balasubbramanian D., Baranwal G., Clark M.C., Goodlett B.L., Mitchell B.M, & Rutkowski J.M. (2020). Kidney-specific lymphangiogenesis increases sodium excretion and lowers blood pressure in mice. Journal of hypertension, 38(5), 874-885.

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Quantifying Salivary Alpha-Amylase Activity

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The salivary alpha-amylase activity was measured by a commercial method (a-Amylase, OSR6182, Beckman Coulter) previously validated in porcine saliva [26 (link)] in an Olympus AU400 autoanalyzer (Beckman Olympus AU400 Chemistry Analyzer, Beckman Coulter, Brea, CA, USA).

Ortín-Bustillo A., Botía M., López-Martínez M.J., Martínez-Subiela S., Cerón J.J., González-Bulnes A., Manzanilla E.G., Goyena E., Tecles F, & Muñoz-Prieto A. (2023). Changes in S100A8/A9 and S100A12 and Their Comparison with Other Analytes in the Saliva of Pigs with Diarrhea Due to E. coli. Animals : an Open Access Journal from MDPI, 13(16), 2556.

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Routine Laboratory Investigations Protocol

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Routine laboratory investigations were done for all subjects, including complete blood count (CBC), international normalized ratio (INR), serum alanine transaminase (ALT), aspartate transaminase (AST), albumin, total bilirubin (T-Bil), alkaline phosphatase (ALP), γ-glutamyl transpeptidase (GGT), blood urea nitrogen (BUN) and creatinine. Routine chemistry tests were done on an Olympus AU 400 autoanalyzer (Beckman Coulter International SA, Nyon, Switzerland). Serum levels of a-fetoprotein (AFP) were measured by solid phase two sequential chemiluminescent immunometric assay using an Immulite 1000 system analyzer (Siemens Healthineers GmbH, Erlangen, Germany), and values up to 20 ng/ml were considered normal.

Nomair A.M., Issa N.M., Madkour M.A, & Shamseya M.M. (2020). The clinical significance of serum miRNA-224 expression in hepatocellular carcinoma. Clinical and Experimental Hepatology, 6(1), 20-27.

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