MRI investigations were performed for all patients by using a Discovery MR 750 3 T MRI system (GE Healthcare, Milwaukee, Wisconsin, USA). Firstly, T1-weighted (T1w) images were acquired using an Inversion-Recovery Fast Spin-Echo sequence with repetition time (TR) of 1593 msec and echo time (TE) of 24 msec, and T2-weighted (T2w) images were obtained by using a FSE sequence (TR/TE, 4600 msec/110 msec). Next, DWI was performed using a single-shot, echo-planar sequence (TR/TE, 4000 msec/112 msec; matrix, 128 × 128; Field of View (FOV), 24 × 24 cm2; and slice thickness, 4 mm). A total of 16 b values were acquired in three orthogonal directions at 0, 50, 100, 150, 200, 300, 400, 500, 800, 1000, 1500, 2000, 2500, 3000, 4000 and 5000 sec/mm2. Total acquisition time for DWI was 5 minutes 32 seconds. Finally, the T1w sequence was repeated after intravenous administration of 0.1 mmol/kg gadopentetate dimeglumine.
Discovery mr750 3t mri system
Manufactured by GE Healthcare
Sourced in United States
The Discovery MR750 3T MRI system is a magnetic resonance imaging device manufactured by GE Healthcare. It operates at a magnetic field strength of 3 Tesla and is designed for diagnostic imaging purposes.
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4 protocols using discovery mr750 3t mri system
1
Comprehensive MRI Evaluation Protocols
2
Functional Neuroimaging with 3T MRI System
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Functional magnetic resonance imaging (fMRI) was performed with a GE Healthcare Discovery MR750 3‐T MRI system (General Electric, Milwaukee, WI) with an eight‐channel phased‐array head coil. The participants were instructed to lie in a supine position and to minimize thinking and head movements during scanning. The neuroimaging parameters were as follows: 2,000‐ms repetition time (TR), 45‐ms echo time (TE), 32 slices, 4‐mm slice thickness, 0.5‐mm gap, 220 × 220 field of view, 64 × 64 acquisition matrix, and 90° flip angle. The scans were acquired with parallel imaging and SENSitivity Encoding (factor = 2). Structural images were obtained with a high‐resolution three‐dimensional turbo‐fast echo T1‐weighted sequence with the following parameters: 8.2/3.2‐ms TR/TE, 170 slices, 1‐mm thickness, no gap, 256 × 256 field of view, 256 × 256 acquisition matrix, and 12° flip angle.
3
Optimized Multi-shell dMRI Acquisition
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A total of 12 preflight, 12 post-flight, and 8 follow-up diffusion MRI scans were acquired using a GE Discovery MR750 3T MRI system equipped with a 16-channel receiver head coil using a twice refocused pulsed gradient spin-echo echo-planar imaging sequence. An optimized multi-shell dMRI acquisition scheme was prescribed, containing diffusion weightings of b = 0, 700, 1200, and 2800 s/mm2, applied in 8, 25, 45, and 75 directions, respectively (Jeurissen et al., 2014 (link)). In addition, 3 b = 0 s/mm2 images were acquired with reversed-phase encoding, for the purpose of correcting susceptibility-induced distortions. Other imaging parameters were: repetition/echo time of 7800/100 ms, voxel size of 2.4 × 2.4 × 2.4 mm3, matrix size of 100 × 100, 58 slices, and 1 excitation. Imaging was accelerated by a factor of 2 using the Array coil Spatial Sensitivity Encoding Technique. The total acquisition time was 21 min and 23 s.
4
Multi-shell Diffusion MRI Acquisition
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Data were acquired on a GE Discovery MR750 3T MRI system equipped with a 16-channel receiver head coil using a twice refocused pulsed gradient spin-echo echo-planar imaging sequence. An optimized multi-shell dMRI acquisition scheme was prescribed, containing diffusion weightings of b = 0, 700, 1200, and 2800 s/mm2, applied in 8, 25, 45, and 75 directions, respectively (15 (link)). In addition, three b = 0 s/mm2 images were acquired with reversed phase encoding, for the purpose of correcting susceptibility-induced distortions (33 (link)). Other imaging parameters were: repetition/echo time of 7800/100 ms, voxel size of 2.4 mm × 2.4 mm × 2.4 mm, matrix size of 100 × 100, 58 slices, and 1 excitation. Imaging was accelerated by a factor of 2 using the Array coil Spatial Sensitivity Encoding Technique. The total acquisition time was 21 min and 23 s.
In addition, T1-weighted structural scans were acquired using a three-dimensional fast spoiled gradient-echo sequence to aid the identification of anatomical structures. Imaging parameters were repetition/echo time of 8/3 ms, flip angle of 12°, field of view of 240 mm, voxel size of 1 mm × 1 mm × 1 mm, matrix size of 240 × 240, 180 slices, and 1 excitation.
In addition, T1-weighted structural scans were acquired using a three-dimensional fast spoiled gradient-echo sequence to aid the identification of anatomical structures. Imaging parameters were repetition/echo time of 8/3 ms, flip angle of 12°, field of view of 240 mm, voxel size of 1 mm × 1 mm × 1 mm, matrix size of 240 × 240, 180 slices, and 1 excitation.
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