The postoperative medication regimen included the administration of topical levofloxacin (Santen Pharmaceutical, Osaka, Japan) four times per day for 1 week and then 0.1% fluorometholone eye drops (Santen Pharmaceutical, Osaka, Japan) from eight times to one time per day over 24 days in a sequential decreasing order. Lacrimal substitutes were also used four times per day from 1 to 3 months, as required.
Mel 80 excimer laser
The Mel 80 excimer laser is a medical device designed for ophthalmic procedures. It utilizes ultraviolet laser light to precisely reshape the cornea, a process known as photorefractive keratectomy (PRK) or laser-assisted in-situ keratomileusis (LASIK). The Mel 80 excimer laser operates at a wavelength of 193 nanometers and is capable of delivering controlled pulses of laser energy to the corneal surface.
Lab products found in correlation
11 protocols using mel 80 excimer laser
Femtosecond-Assisted Customized LASIK
The postoperative medication regimen included the administration of topical levofloxacin (Santen Pharmaceutical, Osaka, Japan) four times per day for 1 week and then 0.1% fluorometholone eye drops (Santen Pharmaceutical, Osaka, Japan) from eight times to one time per day over 24 days in a sequential decreasing order. Lacrimal substitutes were also used four times per day from 1 to 3 months, as required.
Corneal Refractive Surgery Protocols
SMILE was performed using the VisuMax femtosecond laser system (Carl Zeiss Meditec) with a repetition rate of 500 kHz, pulse energy of 185–190 nJ, intended cap thickness of 100–120 μm, cap diameter of 7.5 mm, lenticule diameter of 6.1 to 6.6 mm (depending on the refractive error), and a 90°-angle side cut with a circumferential length of 2.1 mm at the superior position.
FS-LASIK was performed with the VisuMax system for flap creation followed by Mel 80 excimer laser (Carl Zeiss Meditec) for stromal ablation, with an intended flap thickness of 95 μm and pulse energy of 185 nJ. The hinge was located at the superior position.
A standard postoperative topical steroid (Fluorometholone 0.1%) was tapered over 30 days; topical antibiotic (Tobramycin 0.003%) QID for 7 days, and unpreserved ocular lubricant 4 times a day was prescribed for a month.
Corneal Refractive Surgery Techniques
FS-LASIK was performed using a 500 kHz VisuMax femtosecond laser (Carl Zeiss Meditec AG, Jena, Germany) for flap creation and a 250 Hz MEL-80 excimer laser (Carl Zeiss Meditec AG, Jena, Germany) for stromal ablation at the following settings for all the eyes: pulse energy of 185 nJ, flap diameter of 8.0 mm, flap thickness of 90 μm, hinge length of 4.0 mm, and optical zone diameter of 6.2–6.8 mm. In all patients, bandage soft contact lenses (ACUVE OASYS, Inc., FL, USA) were applied for 1 day after surgery.
All surgeries were performed by the same skilled surgeon in both procedures (XZ).
Both groups received the same postoperative topical medications: levofloxacin 4 times per day for 7 days; 0.1% fluorometholone 8 times per day tapered to 1 time per day over 24 days, and artificial tears 4 times per day for 1 month.
Femtosecond Laser-Assisted SMILE and LASIK Procedures
In the FS-LASIK procedures, the same femtosecond laser system was used for flap creation with a pulse energy of 185 nJ, followed by a MEL 80 excimer laser (Carl Zeiss Meditec, Oberkochen, Germany) for stromal ablation with a repetition rate of 250 Hz and a pulse energy of 1.00±0.15 mJ. The intended flap thickness was set to 100 μm with a diameter of 8 mm. The hinges were located at a superior 12 o’clock with a length of 4.0 mm.
All surgeries were performed by an experienced surgeon (XTZ). Prior to surgery, 0.5% topical levofloxacin (Cravit; Santen, Osaka, Japan) was applied four to six times daily for 3 days. A bandage soft contact lens was applied for 1 day after FS-LASIK. After both procedures, 0.5% topical levofloxacin, 0.1% fluorometholone solution and non-preserved artificial tears (carboxymethylcellulose sodium eye drops; Allergan, Irvine, California, USA) were applied.
Femtosecond Laser-Assisted LASIK Protocol
Comparison of LASIK and SMILE Procedures
Postoperatively, patients in both groups received polymyxin/ neomycin/ dexamethasone eye-drops (Isopto-Max, Alcon) 4 times daily for 5 days. For 4 weeks, artificial tear supplements were prescribed, starting hourly the first week and reduced to weekly as needed.
Refractive Laser Procedures: SMILE and LASEK
Comparison of LASEK and Epi-LASIK Procedures
During Epi-LASIK, the rotational Epi-LASIK microkeratome (KM-5000D, Wuxi Kangming Medical Device Corp, Wuxi, China) was used to create the epithelial sheet.9 The remainder of the procedure closely mirrored the LASEK procedure.
Mitomycin C was not used in either LASEK or Epi-LASIK cases. Bandage contact lenses were removed when epithelialisation was complete (usually between postoperative days 3 and 7).
Corneal Refractive Surgery Techniques
SMILE and FS-LASIK Procedures Compared
FS-LASIK was performed with the VisuMax system for flap creation followed by Mel 80 excimer laser (Carl Zeiss Meditec) for stromal ablation, with an intended flap thickness of 95 mm, optical zone size of 5.75-6.50 mm and pulse energy of 185 nJ. The hinge was located at the superior position. All procedures were performed by one surgeon experienced in both types of procedures. (H.Z).
A standard postoperative topical steroid (Flurometholone 0.1%) tapered over 30 days (or longer if deemed necessary), and topical antibiotic (Tobramycin 0.003%) QID for 7 days was given.
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