Aobs confocal microscope

Manufactured by Leica

The Leica AOBS confocal microscope is a high-performance imaging system designed for advanced microscopy applications. It features an Acousto-Optical Beam Splitter (AOBS) technology that enables rapid and precise control of laser excitation wavelengths, providing efficient separation of excitation and emission signals. The AOBS confocal microscope delivers high-quality, high-resolution images with reduced background fluorescence and improved signal-to-noise ratio.

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SP5-AOBS confocal laser scanning microscope TCS-SP2-AOBS laser scanning spectral inverted confocal microscope Inverted SP5 AOBS confocal microscope TCS-SP2 AOBS Confocal Laser Scanning Microscope SP5 RS AOBS confocal microscope SP2 AOBS confocal laser scanning microscope TCS SP5 X AOBS confocal fluorescence microscope TCS SP5 II AOBS confocal microscope SP5-AOBS X Leica confocal microscope TCS-SP2-AOBS-UV confocal microscope

2 protocols using aobs confocal microscope

Immunohistochemical Analysis of Adult Thymus

Cited 1 time

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Adult thymi were processed for IHC as described (Nowell et al., 2011 (link)). Isotype controls (not shown) were included in all experiments. Staining was analyzed using a Leica AOBS confocal microscope (Leica Microsystems). The images presented are either single optical sections or projected focus stacks of serial optical sections. The number of FOXN1⁺ or AIRE⁺ TECs per area was established by analyzing three areas on each of two non-sequential sections from each of three individual mice. Statistical analysis was performed on the average number of FOXN1⁺ or AIRE⁺ cells per condition.

Bredenkamp N., Nowell C.S, & Blackburn C.C. (2014). Regeneration of the aged thymus by a single transcription factor. Development (Cambridge, England), 141(8), 1627-1637.

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Immunohistochemical Analysis of Thymus

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Adult thymus or thymic rudiment tissue was processed for immunohistochemistry as described [29] (link). Isotype controls (not shown) were included in all experiments. Staining was analyzed using a Leica AOBS confocal microscope (Leica Microsystems GmbH). The images presented are either single optical sections or projected focus stacks of serial optical sections.

Jin X., Nowell C.S., Ulyanchenko S., Stenhouse F.H, & Blackburn C.C. (2014). Long-Term Persistence of Functional Thymic Epithelial Progenitor Cells In Vivo under Conditions of Low FOXN1 Expression. PLoS ONE, 9(12), e114842.

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