17 octadecynoic acid

Manufactured by Cayman Chemical

17-Octadecynoic Acid is a long-chain fatty acid used as a research chemical. It provides a molecular structure for various applications in organic synthesis and biochemical studies.

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Lab products found in correlation

2 bromopalmitate 2 bp, by Merck Group (1 mentions) 17 odya, by Cayman Chemical (1 mentions) Bovine serum albumin (bsa), by Merck Group (1 mentions) 20 hete, by Cayman Chemical (1 mentions) 14 15 ee5ze, by Cayman Chemical (1 mentions)

Close spelling variants of this product

17-octadecynoic acid (17-ODYA)

2 protocols using 17 octadecynoic acid

Probing Spike Protein Lipidation

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Expressions of Spike and its various mutants were carried out by transfecting HEK293T cells with 3 μg DNA and PEI. After 36 h the media was replaced with 1 ml of DMEM conditioned with 1%, fatty acid free, Bovine Serum Albumin (BSA; Sigma). The same media contained 50 μM 2-bromopalmitate (2BP; Sigma) solubilized in DMSO for 2BP experiments. Post 2 h, cells were fed ∼0.1 mM saponified (41 (link)) fatty acid alkynes 17-Octadecynoic Acid (17-ODYA; Cayman Chemical) or 15-hexadecynoic acid (15-yne; Avanti Polar) dissolved in DMEM condition with 20%, fatty acid free, BSA. After 6 hours cells were harvested into microfuge tubes with two washes of 1× PBS.

Puthenveetil R., Lun C.M., Murphy R.E., Healy L.B., Vilmen G., Christenson E.T., Freed E.O, & Banerjee A. (2021). S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity. The Journal of Biological Chemistry, 297(4), 101112.

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Factors Regulating Retinal Arteriole Dilation

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To identify the factors released from NO-stimulated glial cells, we examined the effects of intravitreal injection of 14,15-EE-5(Z)-E (an analog of EET, 0.7 nmol; Cayman Chemical), 17-octadecynoic acid (an inhibitor of ω-hydroxylase, which mediates conversion of arachidonic acid to 20-HETE, 1.4 nmol; Cayman Chemical), and indomethacin (10 nmol) on intravitreal injection of NOR3 (5 nmol)-induced dilation of retinal arterioles.

Someya E., Akagawa M., Mori A., Morita A., Yui N., Asano D., Sakamoto K, & Nakahara T. (2019). Role of Neuron–Glia Signaling in Regulation of Retinal Vascular Tone in Rats. International Journal of Molecular Sciences, 20(8), 1952.

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