Anti mouse cd279 pd 1 antibody clone 29f 1a12

Manufactured by BioLegend

Sourced in United States

The Anti-mouse CD279 (PD-1) antibody (clone 29F.1A12) is a laboratory reagent used for the detection and analysis of the mouse CD279 (PD-1) protein. CD279, also known as Programmed Cell Death Protein 1 (PD-1), is an inhibitory receptor expressed on activated T cells, B cells, and myeloid cells. This antibody can be used in various immunological assays to study the expression and function of CD279 in mouse models.

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Lab products found in correlation

Sodium deoxycholate, by Merck Group (1 mentions) Navoximod, by MedChemExpress (1 mentions)

Spelling variants of this product

Anti-PD-1 (51 citations) PD-1 (29F.1A12; (19 citations) Anti-PD-1 (clone 29F.1A12, (11 citations) Anti-PD-1 (29F.1A12, (6 citations) Anti-PD-1 antibody (6 citations) PD-1 antibody (6 citations) CD279 (PD-1) (4 citations) Anti-mouse CD279/PD-1 (29F.1A12, (2 citations) Anti-mouse PD-1 (2 citations)

2 protocols using anti mouse cd279 pd 1 antibody clone 29f 1a12

Immunomodulatory Polymer Nanoparticles

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PLGA (15–25 KDa; lactic acid/glycolic acid: 50/50) and methoxy‐PEG‐PLGA (PEG‐PLGA) (2–15 KDa; lactic acid/glycolic acid: 50/50) were obtained from PoliSciTech (USA). Dimethyl sulfoxide (DMSO), acetonitrile and sodium deoxycholate were purchased from Sigma Aldrich (USA). Navoximod was from MedChemExpress (USA) and Adooq Bioscience (USA). Recombinant human INF‐γ and interleukin‐2 (IL‐2) were purchased from Peprotech (USA). Anti‐human PD‐1 antibody (clone EH12.2H7) and anti‐mouse CD279 (PD‐1) antibody (clone 29F.1A12) were sourced from Biolegend (USA). Anti‐human CD28 antibody (clone CD28.2) and anti‐human CD3 (clone OK3) were purchased from ThermoFisher (USA).

Badiee P., Maritz M.F., Dehghankelishadi P., Dmochowska N, & Thierry B. (2023). Hydrophobic ion pairing and microfluidic nanoprecipitation enable efficient nanoformulation of a small molecule indolamine 2, 3‐dioxygenase inhibitor immunotherapeutic. Bioengineering & Translational Medicine, 9(1), e10599.

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PD-1 Blockade in Murine Infections

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In some experiments, the expression of PD-1 on immune cells in mice was blocked by injection of anti-mouse CD279 (PD-1) antibody (clone 29F.1A12, BioLegend, San Diego, CA, USA). Each mouse received 200 µg mAb intraperitoneally (i.p.) every 3 days, starting at 14 days post-infection until 3 days before the mice were sacrificed. For control mice, each was given the same amount of rat IgG2a isotype (clone RTK2758, BioLegend).

Cheng Y., Zhu X., Wang X., Zhuang Q., Huyan X., Sun X., Huang J., Zhan B, & Zhu X. (2018). Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Frontiers in Immunology, 9, 1566.

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