Anti tgf β mab 1d11

Manufactured by R&D Systems

Anti–TGF-β mAb (1D11) is a monoclonal antibody that binds to and neutralizes transforming growth factor beta (TGF-β). This antibody is used in research applications to study the functions and pathways of TGF-β.

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Lab products found in correlation

Il 17a tc11 18h10.1, by BioLegend (2 mentions) Il 21r fc chimera, by R&D Systems (1 mentions) Ifn γ xmg1.2, by BD (1 mentions) Human tgf β, by R&D Systems (1 mentions) Il 23, by R&D Systems (1 mentions) Cyclosporin a, by Merck Group (1 mentions) Rpa 2, by BD (1 mentions)

2 protocols using anti tgf β mab 1d11

Murine Immune Cell Staining

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Antibodies to CD3ε (145-2C11), CD28 (37.51), CD11c (HL3), CD44 (IM7), CD62L (MEL-14), human NGFR (C40-1457), IL-4 (11B11), IL-4 (BDV4-1D11), and IFN-γ (XMG1.2) were purchased from BD. Antibodies to CD8α (53–6.7), B220 (RA3-6B2), Thy1.1 (OX-7), NKp46 (29A1.4), and IL-17A (TC11-18H10.1) were purchased from BioLegend. Antibodies to Foxp3 (FJK-16s), IL-17F (eBio18F10), and γδ TCR (UC7-13D5) were purchased from eBioscience. Murine IL-1β, IL-4, and IL-6 were purchased from PeproTech. Human TGF-β, murine IL-21, IL-23, anti–TGF-β mAb (1D11), and IL-21R-Fc chimera were purchased from R&D Systems.

Tanaka S., Suto A., Iwamoto T., Kashiwakuma D., Kagami S.I., Suzuki K., Takatori H., Tamachi T., Hirose K., Onodera A., Suzuki J., Ohara O., Yamashita M., Nakayama T, & Nakajima H. (2014). Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3. The Journal of Experimental Medicine, 211(9), 1857-1874.

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Detailed Immune Cell Phenotyping

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Antibodies to CD3ε (145-2C11), CD28 (37.51), CD11c (HL3), CD44 (IM7), CD62L (MEL-14), CD69 (H1.2F3), CTLA4 (UC10-4B9), IL-4 (11B11), IL-4 (BDV4-1D11), and IFN-γ (XMG1.2), human NGFR (C40-1457), and human CD2 (RPA-2.10) were purchased from BD Biosciences. Antibodies to CD8α (53–6.7), CD16/32 (93), CD25 (PC61 and 7D4), B220 (RA3-6B2), CD45.1 (A20), CD45.2 (104), FR4 (12A5), IL-6 (MP5-20F3), and IL-17A (TC11-18H10.1) were purchased from BioLegend. Antibodies to Foxp3 (FJK-16s) and Helios (22F6) were purchased from eBioscience. Anti-TGF-β mAb (1D11) and anti–IL-2 mAb (JES6-1A12) were purchased from R&D Systems. Cyclosporin A was purchased from Sigma-Aldrich.

Tanaka S., Suto A., Iwamoto T., Kageyama T., Tamachi T., Takatori H., Suzuki K., Hirose K., Ohara O., Lefebvre V, & Nakajima H. (2018). Sox12 promotes T reg differentiation in the periphery during colitis. The Journal of Experimental Medicine, 215(10), 2509-2519.

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