The largest database of trusted experimental protocols

13 protocols using fluorometholone eye drops

1

Femtosecond-Assisted Customized LASIK

Check if the same lab product or an alternative is used in the 5 most similar protocols
First, corneal flaps, with a super-hinge length of 4.0 mm, located at 12 o’clock, were created using the VisuMax femtosecond laser system. Laser settings were similar to those of SMILE. Once the flap scanning was finished, it was manually lifted using a spatula and gently positioned in the upper cornea. Subsequently, stromal ablation was performed using the MEL 80 excimer laser (Carl Zeiss Meditec AG, Germany) system, with parameters programmed as 500 Hz repetition rate. The diameter and thickness of the flap were 7.5 mm and 110 μm, respectively. The optical zone varied from 5.75 to 6.25 due to the corneal thickness and refractive errors. Bandage soft contact lenses were placed to protect each eye for 1 day and removed at the following day. The same surgeon completed all the procedures uneventfully (XZ).
The postoperative medication regimen included the administration of topical levofloxacin (Santen Pharmaceutical, Osaka, Japan) four times per day for 1 week and then 0.1% fluorometholone eye drops (Santen Pharmaceutical, Osaka, Japan) from eight times to one time per day over 24 days in a sequential decreasing order. Lacrimal substitutes were also used four times per day from 1 to 3 months, as required.
+ Open protocol
+ Expand
2

Postoperative Ocular Management Regimen

Check if the same lab product or an alternative is used in the 5 most similar protocols
Postoperatively, 0.5% ofloxacin eye drops (Santen Pharmaceutical Co., Ltd., Osaka, Japan) were applied 4 times a day for 1 week, 0.1% fluorometholone eye drops (Santen Pharmaceutical Co., Ltd.) were applied 4 times daily for 1 month, and 0.3% sodium hyaluronate eye drops (Santen, Pharmaceutical Co., Ltd.) were used 4 times daily for 2–3 months.
Follow-up visits were scheduled on postoperative day 1 and months 1, 3, and 6. UDVA, CDVA, objective and manifested refractions, intraocular pressure, and a slit-lamp examination were included in every follow-up visit. High-resolution tomography (Pentacam HR system), aberrometry (WASCA aberrometer), and overall eye quality measurements using the OQASII system (Visiomereics SL, Barcelona, Spain) were also performed at each postoperative visit with the exception of day 1 after surgery.
+ Open protocol
+ Expand
3

Optical Zone Comparison in LASIK

Check if the same lab product or an alternative is used in the 5 most similar protocols
According to the optical zone used in the surgeries, all patients were divided into three groups: the optical zone was 6.6–6.8 mm in Group A (10 patients, 19 eyes), 6.4–6.5 mm in Group B (10 patients, 19 eyes) and 6.1–6.3 mm in Group C (7 patients, 13 eyes). The average age was (21.32±2.35) in Group A, (20.13±1.96) in Group B, and (21.43±2.01) in Group C. There was no significant difference among the groups (P> 0.05). After surgeries, all patients used 0.1% fluorometholone eye drops and 0.3% levofloxacin eye drops 4 times a day for 1 month (provided by Santen Pharmaceutical Co., China).
+ Open protocol
+ Expand
4

VisuMax Femtosecond Laser Refractive Surgery

Check if the same lab product or an alternative is used in the 5 most similar protocols
All surgeries procedures were performed with the VisuMax femtosecond laser (Carl Zeiss Meditec AG) in the Second Affiliated Hospital of Harbin Medical University. The optical zone was 6.0 to 6.8 mm, and the cap diameter was 7.6 mm. The predetermined cap thickness was 100 to 120 μm, and the pulse energy ranged from 125 to 160 nJ. The side cut was placed at the 10-o’clock position of the cornea with an angle of 120 degrees and a circumferential width of 2 mm. The lenticule was extracted through the incision and all patients received 0.3% ofloxacin eye drops (Santen Pharmaceutical Co., Ltd., Osaka, Japan.) four times a day for 1 week, 0.1% fluorometholone eye drops (Santen Pharmaceutical Co., Ltd.) four times a day for 2 weeks, and 0.1% sodium hyaluronate eye drops (Santen Pharmaceutical Co., Ltd.) four times a day for 2–3 months.
+ Open protocol
+ Expand
5

Postoperative Eye Drop Regimens

Check if the same lab product or an alternative is used in the 5 most similar protocols
Patients in groups II and IV were treated with 0.1% BS eye drops ≥1 h before the surgery. Post-operatively these subjects were treated with 0.1% BS eye drops twice daily for 2 months. Patients in these two groups also received 0.5% levofloxacin eye drops (Santen Pharmaceutical Co., Ltd.) four times per day for 1 month post-operatively to protect from inflammation. Patients from groups I and III were treated with 0.1% DEX/0.3% TOB eye drops four times daily for 1 month after surgery followed by replacement of 0.1% fluorometholone eye drops (Santen Pharmaceutical Co., Ltd.) four times daily for 1 month. Subjects in group V were treated with 0.1% pranoprofen eye drops (Senju Pharmaceutical Co., Ltd.) four times per day, which was started 3 days before the surgery and continued up to 2 months post-surgery. Moreover, patients in all the study groups received 0.5% tropicamide phenylephrine eye drops (Santen Pharmaceutical Co., Ltd.) twice daily for 1 week after the surgery.
+ Open protocol
+ Expand
6

Laser Vision Correction Procedures

Check if the same lab product or an alternative is used in the 5 most similar protocols
In the LASIK procedure, a microkeratome (MK-2000; Nidek, Aichi, Japan) with a 160-μm head was used to create an 8.5-mm corneal flap with a nasal hinge. Laser ablation was performed with a VISX Star S2 or Star S4 excimer laser (AMO, Santa Ana, CA, USA). In all procedures, a 6.0-mm optical zone and conventional ablation were used. After surgery, 0.1% fluorometholone and 0.5% levofloxacin eye drops were prescribed four times daily, starting the day after surgery, for 2 weeks, three times daily for 2 weeks, and then twice daily for 1 month.
In the PRK procedure, the central 6.0-mm diameter epithelium was ablated with an excimer laser. Laser ablation was performed with a VISX Star S or Star S2 excimer laser (AMO). After PRK laser treatment, a bandage soft contact lens was placed on the cornea. Eye drops containing 0.1% betamethasone sodium phosphate (Shionogi Pharmaceutical, Osaka, Japan) and 0.5% levofloxacin (Santen Pharmaceutical, Osaka, Japan) were prescribed four times daily starting the day after surgery for 2 weeks, After 2 weeks, the 0.1% betamethasone sodium phosphate eye drops were terminated, and 0.1% fluorometholone eye drops (Santen Pharmaceutical) were prescribed four times daily for 3 months, three times daily for 2 months, and then twice daily for 2 months.
+ Open protocol
+ Expand
7

Pterygium Excision with Limbal-Conjunctival Autograft

Check if the same lab product or an alternative is used in the 5 most similar protocols
All surgeries were performed by the same team using the same technique [29 (link)]: excision of the pterygium followed by a free limbal-conjunctival autograft taken from a superior position. After surgery, all patients received an identical regimen of topical levofloxacin eye drops (Santen Pharmaceutical, Japan), 0.1% fluorometholone eye drops (Santen Pharmaceutical, Japan), and 0.5% sodium hyaluronate eye drops (Santen Pharmaceutical, Japan), which were tapered off over 1 month. The nylon sutures were removed between day 7 and day 10. Clinical measurements were performed as described in the following.
+ Open protocol
+ Expand
8

Postoperative Eye Medication Regimen

Check if the same lab product or an alternative is used in the 5 most similar protocols
Postoperatively, tobramycin and dexamethasone eye ointment (Alcon, Puurs, Belgium) was used 2–4 times daily for 1–2 weeks and thereafter replaced with 0.1% fluorometholone eye drops (Santen, Osaka, Japan) 4 times daily for 1-2 months, followed by 0.02% fluorometholone eye drops 2–4 times daily (Santen, Osaka, Japan). If necessary, 1% cyclosporine eye drops (Huabei Pharmaceutical Co., Shijiazhuang, China) were administered once or twice per day. The medication was adjusted with the alleviation of inflammation.
+ Open protocol
+ Expand
9

Postoperative Care Protocol for Eye Surgery

Check if the same lab product or an alternative is used in the 5 most similar protocols
Patients were instructed to wear plastic shields for 7 nights. The standard postoperative treatment was levofloxacin eye drops (Cravit; Santen Pharmaceutical Co., Ltd., Osaka, Japan) 4 times a day after surgery for 7 days, fluorometholone eye drops (Santen Pharmaceutical Co., Ltd., Osaka, Japan) at 0.1% 4 times a day for 2 weeks, and preservative-free artificial tears 4 times a day for a month. The patients were followed up at 1 day, 1 week and 1 month, and 3 months; the optometry, visual acuity, and IOP were examined at each visit. Pentacam scanning was performed at the 1-day, 1-month, and 3-month postoperative visits.
+ Open protocol
+ Expand
10

Managing Nonhealing Corneal Ulcers

Check if the same lab product or an alternative is used in the 5 most similar protocols
The primary diseases of nonhealing corneal ulcer in the study included herpes simplex keratitis (HSK), corneal graft ulcer, and Stevens-Johnson syndrome (SJS). Postoperatively, tobramycin and dexamethasone eye drops (Alcon, Puurs, Belgium) were used 4 times daily for 1-2 weeks and then replaced with 0.1% fluorometholone eye drops (Santen, Osaka, Japan) 4 times daily for approximately 1-2 months. For eyes with HSK, antiviral medication was applied topically and systemically with adjuvant corticosteroid eye drops [8 (link), 9 (link)]. Acyclovir eye drops (Wuhan Wujing Pharmaceutical Co., Wuhan, China) were used 4 times every day. Ganciclovir ophthalmic gel (Hubei Keyi Pharmaceutical Co., Wuhan, China) was used every night. Acyclovir was administered orally (8 mg/kg) 3 times daily for 3 months. For eyes with prior corneal transplantation or Stevens-Johnson syndrome, 1% cyclosporine eye drops (Huabei Pharmaceutical Co., Shijiazhuang, China) were used 1–4 times daily.
The medical treatment was adjusted with the alleviation of symptoms and the dissolution of AM. Corneal fluorescein staining was performed daily and the sutures were removed 1–3 weeks postoperatively when the AM dissolved.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!