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Dimethyl succinate

Manufactured by Tokyo Chemical Industry
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Dimethyl-succinate is a chemical compound used in various laboratory applications. It is a clear, colorless liquid with a mild odor. Dimethyl-succinate serves as a versatile reagent and building block in organic synthesis and chemical research.

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Lab products found in correlation

Sodium pyruvate, by Thermo Fisher Scientific (2 mentions) N acetylcysteine nac, by Merck Group (2 mentions) Phospho ampkα thr172, by Cell Signaling Technology (2 mentions) Phospho acc ser79, by Cell Signaling Technology (2 mentions) L glutamine, by Thermo Fisher Scientific (2 mentions) Phospho c jun ser73, by Cell Signaling Technology (2 mentions) Ab28455, by Abcam (2 mentions) Dichlorofluorescin diacetate, by Beyotime (2 mentions) Ab70359, by Abcam (2 mentions) Ab52771, by Abcam (2 mentions) Z vad fmk, by Santa Cruz Biotechnology (2 mentions) 3 mercaptopicolinic acid, by Santa Cruz Biotechnology (2 mentions) Dimethyl 2 oxoglutarate, by Tokyo Chemical Industry (2 mentions) Dimethyl fumarate, by Tokyo Chemical Industry (2 mentions) Dimethyl malate, by Tokyo Chemical Industry (2 mentions) Necrostatin 1, by Santa Cruz Biotechnology (2 mentions) Ampkα, by Cell Signaling Technology (2 mentions) Triethylamine tea, by Merck Group (1 mentions) Toluene, by Sinopharm (1 mentions) Succinic anhydride, by Maclin Biochemical Technology (1 mentions)

3 protocols using dimethyl succinate

1

Metabolic Regulation Pathway Investigation

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3-mercaptopicolinic acid, Z-VAD-FMK and Necrostatin-1 were purchased from Santa Cruz Biotechnology. Dimethyl-2-oxoglutarate, dimethyl-fumarate, dimethyl-succinate and dimethyl-malate were purchased from Tokyo Chemical Industry, Sodium pyruvate and L-glutamine were purchased from Thermo Fisher Scientific, N-acetylcysteine (NAC) was purchased from Sigma-Aldrich, and dichlorofluorescin diacetate from Beyotime.
Antibodies against PCK1 (ab28455, Abcam), PCK2 (ab70359, Abcam) and YAP1 (ab52771, Abcam), phospho-AMPKα (Thr172) (Cell Signaling Technology, 2535), AMPKα (Cell Signaling, 2532), phospho-ACC (Ser79) (Cell Signaling, 11818) and phospho-c-Jun (Ser73) (Cell Signaling, 3270) were purchased commercially.
pBABE-Flag-PCK1 and pQCXIH-Flag-PCK2 were cloned from cDNA provided by Dr. Jiahuai Han (Xiamen University, Xiamen, China). The PB[CMV-myc-YAP-5SA]DS, PB[Act-RFP]DS and Act-PB Transposase plasmids were generous gifts from Dr. Bin Zhao (Zhejiang University, Hangzhou, China). The PB[CMV-flag-PCK1]DS donor plasmids were constructed by excising Act-RFP from the PB[Act-RFP]DS plasmid and ligating the corresponding fragments excised from pQCXIH vectors.
Liu M.X., Jin L., Sun S.J., Liu P., Feng X., Cheng Z.L., Liu W.R., Guan K.L., Shi Y.H., Yuan H.X, & Xiong Y. (2018). Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma. Oncogene, 37(12), 1637-1653.
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2

Metabolic Regulation Pathway Investigation

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3-mercaptopicolinic acid, Z-VAD-FMK and Necrostatin-1 were purchased from Santa Cruz Biotechnology. Dimethyl-2-oxoglutarate, dimethyl-fumarate, dimethyl-succinate and dimethyl-malate were purchased from Tokyo Chemical Industry, Sodium pyruvate and L-glutamine were purchased from Thermo Fisher Scientific, N-acetylcysteine (NAC) was purchased from Sigma-Aldrich, and dichlorofluorescin diacetate from Beyotime.
Antibodies against PCK1 (ab28455, Abcam), PCK2 (ab70359, Abcam) and YAP1 (ab52771, Abcam), phospho-AMPKα (Thr172) (Cell Signaling Technology, 2535), AMPKα (Cell Signaling, 2532), phospho-ACC (Ser79) (Cell Signaling, 11818) and phospho-c-Jun (Ser73) (Cell Signaling, 3270) were purchased commercially.
pBABE-Flag-PCK1 and pQCXIH-Flag-PCK2 were cloned from cDNA provided by Dr. Jiahuai Han (Xiamen University, Xiamen, China). The PB[CMV-myc-YAP-5SA]DS, PB[Act-RFP]DS and Act-PB Transposase plasmids were generous gifts from Dr. Bin Zhao (Zhejiang University, Hangzhou, China). The PB[CMV-flag-PCK1]DS donor plasmids were constructed by excising Act-RFP from the PB[Act-RFP]DS plasmid and ligating the corresponding fragments excised from pQCXIH vectors.
Liu M.X., Jin L., Sun S.J., Liu P., Feng X., Cheng Z.L., Liu W.R., Guan K.L., Shi Y.H., Yuan H.X, & Xiong Y. (2018). Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma. Oncogene, 37(12), 1637-1653.
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3

Organocatalytic Ring-Opening Polymerization

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All manipulations involving air- and/or water-sensitive compounds were carried out with the standard Schlenk and vacuum line techniques under an argon atmosphere or in a nitrogen-filled glovebox. Succinic anhydride (SA) and citraconic anhydride (CA) were purchased from Macklin. Propylene epoxide (PO) was purchased from Aldrich. Chromatographic purity solvents, including toluene, dichloromethane, tetrahydrofuran (THF), ethanol, and flaky sodium hydroxide (CaH2), were bought from SINOPHARM. Triethyl borane (TEB) in tetrahydrofuran solution (1.0 mol/L), Dimethyl succinate (DS), and dimethyl citraconate (DC) were purchased from the Tokyo Chemical Industry (TCI). Triethylamine (TEA) was purchased from Aldrich, and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (mTBD) and 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) were purchased from TCI. PO, TEA, DBU, DS, DC, and toluene were refluxed over CaH2 for 24 h and vacuum-distilled prior to use. In particular, chloroform-d for dynamic NMR characterization of amine-ester complexes was refluxed over CaH2 for 24 h and distilled prior to use. Both the anhydrides (SA and CA) were purified by vacuum sublimation three times. The purified anhydrides were collected under an inert atmosphere and stored in the glovebox for use. Other organic reagents were used without purification.
Chu B., Liu X., Xiong Z., Zhang Z., Liu B., Zhang C., Sun J.Z., Yang Q., Zhang H., Tang B.Z, & Zhang X.H. (2024). Enabling nonconjugated polyesters emit full-spectrum fluorescence from blue to near-infrared. Nature Communications, 15, 366.
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