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7 protocols using optima ct680 series

1

Abdominal CT Contrast Imaging Protocol

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All patients underwent contrast-enhanced abdominal CT using the following multidetector row CT systems: BrightSpeed, Optima CT680 Series (GE Medical Systems), and Siemens Somatom Definition AS 64, Perspective (Siemens Medical Systems). The acquisition parameters were as follows: tube voltage, 120–130 kV; tube current, 150–300 mAs; reconstructed axial-section thickness 5 mm, slice interval 5 mm, pitch 0.6. The contrast agents were Ultravist (Bayer Schering Pharma, Berlin, Germany), Optiray (Liebel-Flarsheim Canada Inc., Kirkland, Quebec, Canada), and Iohexol (Beijing North Road Pharmaceutical Co. Ltd., Beijing, China). A total of 70–100 ml of contrast agent was administered using a pump injector into an antecubital vein. Arterial phase and portal venous phase contrast-enhanced CT scans were performed after delays of 30–35 s and 50–60 s after injection of the contrast medium, respectively.
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2

CT Imaging Protocol for Contrast-Enhanced Abdominal Scans

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All patients fasted from solid food for approximately 4-6 hours before the examinations. The CT scans were performed with the following equipment: Siemens Somatom definition AS 64、Perspective (Siemens Medical Systems), TOSHIBA Aquilion 320 (TOSHIBA Medical Systems Corporation), and Optima CT680 Series (GE Medical Systems). The imaging parameters were as follows: kVp/effective mA = 120 Kv/160-250 mAs, slice thickness = 5 mm; and field of view = 320-380 mm. A plain scan was performed, followed by intravenous injection of nonionic contrast medium (Omnipaque 300 g/l; GE Healthcare; iopromide; Ultravist 370, Bayer Schering Pharma, 120 mL) at a rate of 3 mL/s. Images were obtained in the arterial phase (23-25 s), portal venous phase (40 s) and equilibrium phase (70 s).
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3

Computed Tomography Enterography Protocol

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CTE was undertaken using a conventional protocol. All patients underwent standardized preparation of the intestine before examination. Patients fasted for 12 h before CTE, and isotonic solution (1500 mL) was administered in equal doses 45, 30, and 15 min before CTE. A Revolution® CT system (GE Healthcare, Chicago, IL, USA) was used for CTE in the First Affiliated Hospital of Anhui Medical University. An Optima CT680 Series (GE Healthcare) was employed in the High-tech Hospital of the First Affiliated Hospital of Anhui Medical University. A Somatom® Definition Flash CT system (Siemens, Hamburg, Germany) was used in the First Affiliated Hospital of Wannan Medical College. The tube voltage was 100–140 kV, tube current was 150–300 mA, the acquisition matrix was 512 × 512, layer thickness and layer spacing were 5 mm, respectively. Contrast agent (320 mgI/mL) was injected at 1.5 mL/kg bodyweight via peripheral veins at 3.0 mL/s. Similar to other small intestinal radiomics studies,19 (link) We used venous phase CTE images after a delay of 70 seconds to delineate lesions and extract image features.
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4

Multi-Modality CT Imaging Protocol

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CT images were collected using multi-detector CT (MX 16, Phillips, Cleveland, Netherlands; BrightSpeed, Siemens, Erlangen, Germany; SOMATOM Perspective, Siemens, Erlangen, Germany; Optima CT680 Series, GE MEDICAL SYSTEMS, America; Aquilion, TOSHIBA, Japan; Emotion 16, Siemens, Erlangen, Germany). All patients were scanned in the supine position with their breath held at the end of inspiration. The field of view was set from the apex to the base of the lungs. The tube voltage and the current were 120 kV and 30–140 mA, respectively. All data were reconstructed using a standard reconstruction kernel. The reconstruction matrix was 512 × 512, and the slice thickness of reconstructed sections was between 0.625 mm and 1 mm. Images were viewed at window settings optimized for the assessment of the lung parenchyma (width 1500 HU; level −500 HU).
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5

Multidetector CT Angiography Parameters

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CTA scanning was performed with various multidetector row spiral CT devices, including the Discovery CT750 HD (GE Healthcare), Revolution CT (GE Healthcare), SOMATOM Definition AS (Siemens Healthineers), SOMATOM Definition Flash (Siemens Healthineers), Optima CT680 Series (GE Healthcare), and Philips Ingenuity CT (Philips Healthcare). A tube voltage of 100–120 kV was used for all patients, and the tube current ranged from 116 mA to 656 mA. Aortic CTA scanning was performed from the level of the thoracic inlet to the pelvic floor after the injection of intravenous contrast material. The other relevant parameters are as follows: pixel spacing, 0.49–0.90 mm; reconstruction slice thickness, 0.625–1.25 mm; matrix, 512 × 512. The total number of CTA slices was 106,426 in all patients, with an average of 985 ± 299.5.
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6

Multi-modal CT Imaging Analysis

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In the course of imaging examination, all subjects underwent chest-enhanced CT scanning through multi-detector CT system: Bright Speed, Optima CT 680 Series (GE Medical Systems), Siemens Somatom definition AS 64, and Perspective (Siemens Medical Systems). The scanning parameters set during inspection are as follows: detector configuration 128×0.6 mm; tube voltage, 120–130 kV; tube current, 150–300 mAs; thickness, 5 mm; and pitch, 0.6. According to the obtained image, tumor segmentation and feature extraction were performed.
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7

Non-Contrast Volumetric CT Imaging Protocol

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CT examinations were performed using multi-detector CT scanners (MX 16, Phillips, Cleveland, Netherlands; BrightSpeed, SOMATOM Perspective, and Emotion 16, all from Siemens, Erlangen, Germany; Optima CT680 Series, GE MEDICAL SYSTEMS, America; Aquilion, TOSHIBA, Japan) without any contrast media on all scans. Volumetric CT acquisitions were implemented. Patients were requested to place in the supine position with their breath held for undergoing scanning. The scan was performed at the end of inspiration from the apex of the lung to the base of the lung. The tube voltage was 120 kVp with auto current ranging from 30 mA to100 mA. The field of view was 31 cm∼31 cm×36 cm∼36 cm. CT images were reconstructed with a matrix size of 512×512. The scan thickness and the increment were both 5 mm, the reconstruction thickness was 1 mm∼1.5 mm in transverse slice orientation. All the images were reconstructed by the standard kernel.
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