Marker 7700

The PXRD patterns of the MOFs were recorded using a Rigaku MiniFlex diffractometer (Rigaku Corp., Neu-Isenburg, Germany). FT–IR spectroscopy was performed using an INVENIO-R (Bruker, Billerica, MA, USA). The surface morphologies of the MOFs were characterized by SEM (JSM-5800F, JEOL, Tokyo, Japan). Inductively coupled plasma mass spectrometry (ICP–MS, Agilent Marker 7700, RF Generator Power 1550W, Tokyo, Japan) measurements were performed in the Seoul Center of the Korea Basic Science Institute. The fluorescence intensity was read with a microplate reader (BioTek, Winooski, VT, USA), and the stained cells were imaged by a fluorescence microscope (ECLIPSE Ni-U, Nikon Co., Tokyo, Japan).

PXRD patterns of Cu-MOF, PS, and PS@Cu-MOF were recorded using a Rigaku MiniFlex diffractometer (Rigaku Corp, Neu-Isenburg, Germany). The FT-IR spectrum was measured on a Bio-Rad FTS 135 spectrometer (Hercules, CA, USA). DSC runs were carried out using a DSC 214 Polyma (NETZSCH, Burlington, MA, USA). TGA was performed using a TG 209 F3 Tarsus^® instrument (NETZSCH, Burlington, MA, USA). The surface morphology and elemental composition of PS and the PS@Cu-MOF scaffolds were characterized using SEM-EDS (FE-SEM, JEOL JSM-5800F, Peabody, MA, USA). The mechanical properties of PS and PS@Cu-MOF were evaluated using a TA rheometer (Discovery HR 10, New Castle, DE, USA). The degradation of PS@Cu-MOF was carried out by ICP-MS (Agilent Marker 7700, RF Generator Power 1550 W, Tokyo, Japan). The colorimetric absorbance was determined using a microplate reader (Synergy H1, BioTek, Winooski, VT, USA), and the live/dead double-stained cells were imaged by fluorescence microscopy (IX83, Olympus, Center Valley, PA, USA).