A dual-head, variable-angle gamma camera (Discovery630; GE Healthcare Life Sciences, Amersham Place, Little Chalfont, Buckinghamshire HP7 9NA, England) with high-resolution low-energy collimators acquired with a 256 × 256 matrix size (zoom 1.0) was used to perform lung perfusion scintigraphy. To ensure optimal radiopharmaceutical distribution in the lungs, each patient initially received half of the 200-MBq 99mTc microalbumin/99mTc-macroaggregate solution in prone position, followed by the other half with the patient in supine position. After intravenous administration, planar scans were obtained in eight projections: anterior, posterior, left lateral, right lateral, right anterior oblique, right posterior oblique, left anterior oblique, and left posterior oblique (1 million counts each). Images were processed using an automated software for quantitative perfusion analysis which was available at a Xeleris image-processing station. This software automatically divides both lungs into three regions of interest in AP and PA projections and calculates geometric mean values from both projections in all six ROIs.
Discovery 630
Manufactured by GE Healthcare
Sourced in Israel, United Kingdom
The Discovery 630 is a compact and versatile medical imaging system designed for a variety of clinical applications. It features advanced imaging technologies that enable high-quality visualization of anatomical structures and physiological processes. The system's core function is to acquire and process medical images, providing healthcare professionals with the necessary diagnostic information to support patient care.
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Lab products found in correlation
5 protocols using discovery 630
1
Quantitative Lung Perfusion Scintigraphy
2
Cardiac Imaging with 99mTc-PYP SPECT/CT
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Each study subject was intravenously injected with a ~ 740-MBq 99mTc-PYP dose prepared by Beijing SHIHONG Pharmaceutical Center and calibrated by a radioactivity meter (CRC-25R, CAPINTEC, USA). Relevant parameters including injection dose, time, and site were properly recorded. Post the 99mTc-PYP injection for 1 h, a planar scan was performed in anterior and left lateral views for 10 min and then followed by a SPECT scan in the thorax position on a dual-head SPECT camera (Discovery 630, GE Healthcare, Haifa, Israel). The SPECT camera consists of low-energy high-resolution collimator with 9.53 mm thickness of NaI(Tl) scintillation crystal. With patient’s heart positioned in the center field of view, planar images were acquired for a total of 750,000 counts with 256 × 256 matrix and 1.46 zoom factor. Imaging parameters for SPECT acquisition utilized 128 × 128 matrix, circular orbit (radius 30 cm), 180° arc, step-and-shoot, 30 steps at 40 s/step, zoom = 1.0, and multiple energy windows (126–154 keV and 109–125 keV). After the completion of SPECT acquisition, a low-dose free-breathing CT scan (120 keV, 35 mA, 12 s) was separately acquired on a dedicated PET/CT scanner (Sinounion Polar Star m660, Beijing, China) for attenuation correction of SPECT images and image fusion. The patient positioning between two scans was optimally consistent to avoid non-translational misregistration.
3
Planar Perfusion Scintigraphy for Lung Blood Flow
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PPS was performed using a dual-head gamma camera (Discovery630; GE Healthcare Life Sciences, Amersham Place, Little Chalfont, Buckinghamshire HP7 9NA, England). Patients were administered with half of the 200-MBq 99mTc microalbumin/99mTc-macroaggregate solution intravenously in the prone position, and with the other half in the supine position. Subsequently, the images obtained by plane scan were subjected to quantitative perfusion analysis. Geometric mean values were calculated from anterior-to-posterior and posterior-to-anterior projections of the bilateral lungs, which were divided into six regions of interest.
The BFR, calculated by planar perfusion scintigraphy, did not consider the spatial overlap of blood flow in each lung lobe due to the low spatial resolution of imaging under respiratory movement.
The BFR, calculated by planar perfusion scintigraphy, did not consider the spatial overlap of blood flow in each lung lobe due to the low spatial resolution of imaging under respiratory movement.
4
Cardiac 99mTc-PYP SPECT/CT Imaging
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Each study subject was intravenously injected with a ~740MBq 99m Tc-PYP dose prepared by Beijing SHIHONG Pharmaceutical Center and calibrated by a radioactivity meter (CRC-25R, CAPINTEC, USA).
Relevant parameters including injection dose, time and site were properly recorded. Post the 99m Tc-PYP injection for one hour, a planar scan was performed in anterior and left lateral views for 10 minute and then followed by a SPECT scan in the thorax position on a dual-head SPECT camera (Discovery 630, GE Healthcare, Haifa, Israel). The SPECT camera consists of low-energy high-resolution collimator with 9.53 mm thickness of NaI(Tl) scintillation crystal. With patient's heart positioned in the center eld of view, planar images were acquired for a total of 750,000 counts with 256x256 matrix and 1.46 zoom factor.
Imaging parameters for SPECT acquisition utilized 128x128 matrix, circular orbit (radius 30 cm), 180 o arc, step-and-shoot, 30 steps at 40 secs/step, zoom=1.0 and multiple energy windows (126-154keV and 109-125keV). After the completion of SPECT acquisition, a low-dose free-breathing CT scan (120 keV, 35 mA, 12 sec) was separately acquired on a dedicated PET/CT scanner (Sinounion Polar Star m660, Beijing, China) for attenuation correction of SPECT images and image fusion. The patient positioning between two scans was optimally consistent to avoid non-translational misregistration.
Relevant parameters including injection dose, time and site were properly recorded. Post the 99m Tc-PYP injection for one hour, a planar scan was performed in anterior and left lateral views for 10 minute and then followed by a SPECT scan in the thorax position on a dual-head SPECT camera (Discovery 630, GE Healthcare, Haifa, Israel). The SPECT camera consists of low-energy high-resolution collimator with 9.53 mm thickness of NaI(Tl) scintillation crystal. With patient's heart positioned in the center eld of view, planar images were acquired for a total of 750,000 counts with 256x256 matrix and 1.46 zoom factor.
Imaging parameters for SPECT acquisition utilized 128x128 matrix, circular orbit (radius 30 cm), 180 o arc, step-and-shoot, 30 steps at 40 secs/step, zoom=1.0 and multiple energy windows (126-154keV and 109-125keV). After the completion of SPECT acquisition, a low-dose free-breathing CT scan (120 keV, 35 mA, 12 sec) was separately acquired on a dedicated PET/CT scanner (Sinounion Polar Star m660, Beijing, China) for attenuation correction of SPECT images and image fusion. The patient positioning between two scans was optimally consistent to avoid non-translational misregistration.
5
Cardiac 99mTc-PYP SPECT/CT Imaging
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Each study subject was intravenously injected with a ~740MBq 99m Tc-PYP dose prepared by Beijing SHIHONG Pharmaceutical Center and calibrated by a radioactivity meter (CRC-25R, CAPINTEC, USA).
Relevant parameters including injection dose, time and site were properly recorded. Post the 99m Tc-PYP injection for one hour, a planar scan was performed in anterior and left lateral views for 10 minute and then followed by a SPECT scan in the thorax position on a dual-head SPECT camera (Discovery 630, GE Healthcare, Haifa, Israel). The SPECT camera consists of low-energy high-resolution collimator with 9.53 mm thickness of NaI(Tl) scintillation crystal. With patient's heart positioned in the center eld of view, planar images were acquired for a total of 750,000 counts with 256x256 matrix and 1.46 zoom factor.
Imaging parameters for SPECT acquisition utilized 128x128 matrix, circular orbit (radius 30 cm), 180 o arc, step-and-shoot, 30 steps at 40 secs/step, zoom=1.0 and multiple energy windows (126-154keV and 109-125keV). After the completion of SPECT acquisition, a low-dose free-breathing CT scan (120 keV, 35 mA, 12 sec) was separately acquired on a dedicated PET/CT scanner (Sinounion Polar Star m660, Beijing, China) for attenuation correction of SPECT images and image fusion. The patient positioning between two scans was optimally consistent to avoid non-translational misregistration.
Relevant parameters including injection dose, time and site were properly recorded. Post the 99m Tc-PYP injection for one hour, a planar scan was performed in anterior and left lateral views for 10 minute and then followed by a SPECT scan in the thorax position on a dual-head SPECT camera (Discovery 630, GE Healthcare, Haifa, Israel). The SPECT camera consists of low-energy high-resolution collimator with 9.53 mm thickness of NaI(Tl) scintillation crystal. With patient's heart positioned in the center eld of view, planar images were acquired for a total of 750,000 counts with 256x256 matrix and 1.46 zoom factor.
Imaging parameters for SPECT acquisition utilized 128x128 matrix, circular orbit (radius 30 cm), 180 o arc, step-and-shoot, 30 steps at 40 secs/step, zoom=1.0 and multiple energy windows (126-154keV and 109-125keV). After the completion of SPECT acquisition, a low-dose free-breathing CT scan (120 keV, 35 mA, 12 sec) was separately acquired on a dedicated PET/CT scanner (Sinounion Polar Star m660, Beijing, China) for attenuation correction of SPECT images and image fusion. The patient positioning between two scans was optimally consistent to avoid non-translational misregistration.
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