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15 channel transmit receive knee coil

Manufactured by Siemens
Sourced in Germany

The 15-channel transmit/receive knee coil is a specialized piece of lab equipment designed for magnetic resonance imaging (MRI) applications. It provides a multi-channel array for efficient signal transmission and reception during MRI scans of the knee region. The coil is constructed to optimize image quality and signal-to-noise ratio for research and diagnostic purposes.

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8 protocols using 15 channel transmit receive knee coil

1

MRI Imaging Protocol for Assessing Axillary Neuropathy

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Examinations were conducted on a 3 Tesla Magnetic Resonance scanner (Magnetom SKYRA, Siemens Healthineers, Erlangen, Germany) between 4/2016 and 8/2018. All AINS patients underwent an MRN protocol including:

A transversal T2-weighted TSE sequence at upper arm level: repetition time/echo time 6980/52 ms, spectral fat saturation, slice thickness 3.0 mm, number of slices 45, interslice gap 0.3 mm, field of view 130 × 130 mm2, acquisition matrix 512 × 358, pixel size 0.254 × 0.254 mm2, number of excitations = 3, acquisition time 7:17 min.

A single-shot spin-echo EPI DTI sequence at upper arm level (b-value = 0 and 1000 s/mm2 in 20 directions): repetition time 4400 ms; echo time 109 ms; fat saturation, spectral adiabatic inversion recovery; field of view 158 × 158 mm2; matrix 128 × 128; slice thickness 3.0 mm; number of slices 18; slice gap 0%; phase oversampling 40%; number of averages 3; parallel imaging, generalized autocalibrating partial parallel acquisition; acceleration factor 3; number of reference lines 84; acquisition time 5:01 min.

Participants were examined in prone position using a 15-channel transmit-receive knee-coil (Siemens Healthcare) with the arm in elbow extension. The magic angle effect was avoided by aligning the longitudinal axis of the upper arm at an angle of 108° relative to the B0 field (Kastel et al., 2011 (link)).
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2

Multimodal MRN of Sciatic Nerve

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All participants received three different MR scans of their sciatic nerve using three different MR scanners: (1) Magnetom Prisma-FIT (bore size 60 cm) (Siemens Healthineers, Erlangen, Germany), (2) Magnetom Skyra (bore size 70 cm) (Siemens Healthineers), and (3) Magnetom TIM-TRIO (bore size 60 cm) (Siemens Healthineers). Every scan was performed in supine position with legs extended using a 15-channel transmit-receive knee coil (Siemens Healthineers), which was placed at mid to distal thigh level. The coil was positioned such that its distal end aligned to the distal patella in order to ensure high reproducibility. Additional pads were used to immobilize the thigh and to avoid motion artifacts. Then, MRN protocols were carried out including high-resolution T2-weighted imaging, DTI and T2 relaxometry. Care was taken that parameters determining contrast and geometry were comparable with respect to the different hardware. Detailed sequence parameters are listed in Table 1. Representative MRN images are shown in Figure 2.
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3

MRI Evaluation of ACL Repair Procedures

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CISS scans (FA=35°; TR=12.78ms; TE=6.39ms; FOV=140mm; 384x384 acquisition matrix with voxel size 0.365mm x 0.365mm x 1.5mm) were acquired from the ongoing clinical trials of the “Bridge Enhanced ACL Repair” (BEAR) procedure (BEAR I Trial: NCT02292004, IRB-P00012985; BEAR II Trial, NCT02664545, IRB-P00021470).29 (link); 31 (link); 32 (link) All MRI scans were performed on a 3T TIM TRIO (Siemens; Erlangen, Germany) with a 15-channel transmit/receive knee coil (Siemens). For the BEAR I Trial, MR images of the surgical limb were acquired at 3, 6, 12, and 24 months post-surgery. For the BEAR II Trial, the MR images were acquired at 6, 12, and 24 months post-surgery. From this dataset, MRI scans were available at multiple timepoints for 76 BEAR subjects (238 MRI scans) and 45 ACLR subjects (120 MRI scans). These MRI scans were randomly divided by subject into 70% training (BEAR n=174, ACLR n=86), 20% validation (BEAR n=45, ACLR n=24), and 10% test sets (BEAR n=19, ACLR n=10).
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4

MR Imaging of Intact ACLs in BEAR Trials

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MR imaging data were acquired from patients participating in the
“Bridge Enhanced ACL Repair (BEAR) I” (NCT02292004; IRB-P00012985; mean age 24.1 ± 4.9 years,
40% male) and “BEAR II” (NCT02664545; IRB-P00021470; mean age 19.4 ± 5.1 years,
42% male) clinical trials evaluating a new ACL repair procedure.28 (link)–30 (link) MR scans of the contralateral intact ACL
were obtained at one timepoint for the BEAR I (24 months post-surgery) and at up
to three timepoints for the BEAR II (6, 12, and 24 months post-surgery)
patients. After accounting for patients lost to follow up and removing patients
with prior or subsequent contralateral ACL tears, a total of 246 sagittal CISS
scans (FA=35°; TR=12.78ms; TE=6.39ms; FOV=140mm; 384x384 acquisition
matrix with voxel size 0.365mm x 0.365mm x 1.5mm) of intact ACLs were included
in the combined dataset. All MR images were acquired on a 3T TRIO (Siemens;
Erlangen, Germany) with a 15-channel transmit/receive knee coil (Siemens). Data
were randomly divided into training (~70%; n=171), validation
(~20%; n=46), and test (~10%; n=29) sets. This split was
stratified by subject to ensure that the model would not learn and make
predictions on MR images from the same subject.
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5

ACL Segmentation from 3T MRI

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MR imaging was performed at 6 months post-surgery, using a 3T magnet (Tim Trio; Siemens) and a 15-channel transmit/receive knee coil (Siemens). Three-dimensional Constructive Interference in Steady State (CISS) sequence (FA=35°; TR=12.78ms; TE=6.39ms; FOV=140mm; 384×384 acquisition matrix with voxel size 0.365mm × 0.365mm × 1.5mm) was acquired of the surgical limb. The ACL was then segmented from the MR image stack by one observer with more than 5 years of experience in ACL segmentation (AMK; inter- and intra- segmenter ICC≥0.93) using commercial imaging software (Mimics; Materialise, Leuven, Belgium).
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6

ACL Imaging and Segmentation Protocol

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MR imaging was performed 6 to 9 months post-surgery on a 3T scanner (Tim
Trio or Prisma; Siemens, Erlangen, Germany) using a 15-channel transmit/receive
knee coil (Siemens). For the BEAR I and II clinical trials, the Constructive
Interference in Steady State (CISS) sequence was acquired for the surgical limb
on the Tim Trio (Table 1). For the BEAR
III trial, both the Tim Trio and Prisma were used (Table 1). Harmonization to standardize the images
between the two scanners was performed as previously described.16 The Prisma scans were scaled
to the Tim Trio scans due to hardware-necessitated differences in the sequence
acquisition parameters (Table 1). The ACL
was then segmented from the MR image stack by an observer with more than 8 years
of experience in ACL segmentation (AMK) using commercial imaging software
(Mimics; Materialise, Leuven, Belgium).
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7

Multiparametric Magnetic Resonance Imaging of Peripheral Nerves

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All subjects were examined in a 3.0 T MR scanner (Magnetom Tim Trio; Siemens Healthineers, Erlangen, Germany) in supine position. A 15-channel transmit-receive knee coil (Siemens Healthineers) was used. The MTI was performed by applying two axial proton density-weighted, gradient echo sequences with and without an off-resonance saturation pulse with otherwise identical parameters and identical positioning at the distal thigh: repetition time: 46 ms; echo times: 4.92 ms, 12.3 ms, 19.68 ms and 27.06 ms; field of view: 160 × 160 mm2; matrix size: 128 × 128; bandwidth: 369 Hz/Px; 24 slices; slice thickness: 4.0 mm; slice gap: 0.8 mm; number of excitations: 1; flip angle: α = 7°; Gaussian envelop, duration = 9984 μs, frequency off-set = 1200 Hz; acquisition time: 2 min 26 s. An adaptive inline image filter was applied to reduce B1 field inhomogeneities (Siemens Healthineers). For precise anatomical nerve segmentation, an axial T2-weighted turbo spin echo sequence was additionally acquired as previously described [12 (link)]: repetition time: 8150 ms; echo time: 54 ms; field of view: 160 × 160 mm2; matrix size: 512 × 333; bandwidth: 181 Hz/Px; 41 slices; slice thickness: 3.5 mm; slice gap: 0.35 mm; number of excitations: 2; flip angle: α = 150°; acquisition time: 4 min 22 s.
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8

3T MRI Evaluation of ACL Reconstruction

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MR imaging was performed at 6 months post-surgery, using a 3T magnet (Tim Trio; Siemens) and a 15-channel transmit/receive knee coil (Siemens). Three-dimensional Constructive Interference in Steady State (CISS) sequence (FA=35°; TR=12.78ms; TE=6.39ms; FOV=140mm; 384×384 acquisition matrix with voxel size 0.365mm × 0.365mm × 1.5mm) was acquired of the surgical limb. The ACL was then segmented from the MR image stack by one observer with more than 5 years of experience in ACL segmentation (AMK; inter-and intrasegmenter ICC≥0.93) using commercial imaging software (Mimics; Materialise, Leuven, Belgium).
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