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Soluble trimeric cd40l

Manufactured by R&D Systems
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Soluble trimeric CD40L is a recombinant protein that consists of the extracellular domain of human CD40 ligand (CD154) trimerized to mimic the natural, membrane-bound form of the protein. CD40 ligand is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) superfamily and is expressed on the surface of activated T cells, where it provides a co-stimulatory signal to B cells.

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Lab products found in correlation

Qcl 1000, by Lonza (1 mentions) Lipopolysaccharide lps from escherichia coli 0111 b4, by Merck Group (1 mentions)

Spelling variants of this product

CD40L (66 citations) Soluble CD40L (3 citations)

2 protocols using soluble trimeric cd40l

1

Endotoxin-free Soluble CD40L Protocol

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Soluble trimeric CD40L was purchased from R&D system, San Diego, CA, USA. Lipoplysaccharide (LPS) from Escherichia coli 0111/B4 was purchased from Sigma Chemical Co. St. Louis, MO, USA. All compounds and media used in this study were analysed for endotoxin contamination using the limulus amebocyte lysate test (QCL-1000, BioWhittaker, Inc, Walkersville, MD, USA). All samples were free of endotoxin contamination (<0.1 EU/ml).
Chimenti M.S., Bergamini A., Triggianese P., Guarino M.D., Gigliucci G., Conigliaro P., Perricone C, & Perricone R. (2016). Expression of immunoglobulin-like transcript 4 as an inhibitory receptor in patients with psoriatic arthritis. The Journal of International Medical Research, 44(1 Suppl), 22-27.
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2

Soluble CD40L and LPS Protocol

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Soluble trimeric CD40L was purchased from R&D system, San Diego CA. Lipopolysaccharide (LPS) from Escherichia coli 0111/B4 was purchased from Sigma Chemical Co. St. Louis, MO.
Bergamini A., Chimenti M.S., Baffari E., Guarino M.D., Gigliucci G., Perricone C, & Perricone R. (2014). Downregulation of Immunoglobulin-Like Transcript-4 (ILT4) in Patients with Psoriatic Arthritis. PLoS ONE, 9(3), e92018.
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