Toluene

Iodized 3-pyridinecarboximidamide (3API) was synthesized by dissolving 1 g of pyridecarboximidamide (98%, Damas-beta) and 2.25 g hydroiodic acid (HI, 57 wt.% in water, Aldrich) in 10 mL ethanol followed by stirring at 0 °C for 6 h for crystallization. The obtained 3API crystals was dissolved in ethanol for recrystallization. The resulting product was dried at 50 °C in a vacuum oven for 24 h. 3APBr and 3APCl were obtained via a similar fabrication procedure.
Formamidinium iodide (FAI), Pb (II) iodide (PbI₂), and spiro-OMeTAD were procured from Advanced Election Technology Co., Ltd. Methylammonium chloride (MACl), Poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine]) (PTAA) and phenylethylammonium iodide (PEAI) were obtained from Xi’an Polymer Light Technology Co. Chlorobenzene (CB) (anhydrous, 99.8%), Toluene (anhydrous, 99.8%) and isopropanol (IPA) (anhydrous, 99.5%) were purchased from Sinopharm Chemical Reagent Co., Ltd. N,N-dimethylformamide (DMF) (anhydrous, 99.8%) and dimethyl sulfoxide (DMSO) (anhydrous, ≥99.9%) were obtained from Alfa Aesar Inc. 4-tert-butylpyridine (t-BP, 99%), bis(trifluoromethane)sulfonamide lithium salt (Li-TFSI, 99.95% trace metals basis), HI solution (55–58 wt.% in water), HBr solution (48 wt.% in water), and HCl (37 wt.% in water), were purchased from Aladdin.

Pd₂(dba)₃ and P(tolyl)₃ were purchased from Sigma-Aldrich (USA). TTBDT (4,8-Bis(5-(2-ethylhexy)thieno[3,2-b]thiophen-2-yl)benzo[1,2-b:4,5-b]dithiophene-2.6-diyl)bis(trimethylstannane)) was purchased from Suna Tech Inc. (Suzhou, China). Tetrahydrofuran, methanol, dichloromethane and toluene were purchased from Sinopharm Chemical Reagent Co. Ltd. (China). 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy[poly(ethylene glycol)]-2000] (DSPE-mPEG2000) was purchased from A.V.T Pharmaceutical (Shanghai, China). DiO and DiR were purchased from Us Everbright Inc. (Suzhou, China). APC-affinity anti-CD11b-antibody was purchased from Thermo Fisher Scientific (USA). Hoechst 33342 was purchased from Sigma-Aldrich (USA). Cell Counting Kit-8 (CCK-8) and the Annexin V-FITC/PI apoptosis detection kit were purchased from Dojindo Laboratories (Kumamoto, Japan). Calcein AM and PI were purchased from J&K Scientific Ltd (Beijing, China). Ultrapure water was prepared by a Milli-Q Gradient System (18.2 M Ω resistivity, Millipore Corporation, Bedford, MA, USA).

The compounds in Table 1 were provided in a standard solution from o2si smart solutions (Charleston, SC, USA) containing 18 PCB congeners (indicator PCBs: 28, 52, 101, 118, 138, 153, and 180; dioxin-like PCBs: 77, 81, 105, 114, 118, 123, 126, 156, 157, 167, 169, and 189) at 10 mg/L each in n-hexane. MWCNTs-COOH (length, 10–30 μm; diameter, 10–20 nm) were purchased from Nanjing XFNANO Materials Tech Co., Ltd. (Nanjing, China). Primary secondary amine (PSA; particle size, 40–60 μm), graphitized carbon black (GCB; particle size, 40–120 μm), and octadecylsilane (C18; particle size, 40–60 μm) were from Tianjin Bonna-Agela Technologies Co., Ltd. (Tianjin, China). n-Hexane was of HPLC grade and purchased from Oceanpak Alexative Chemical., Ltd (Goteborg, Sweden). All other chemical reagents like acetonitrile, acetone, toluene, anhydrous Na₂SO₄, and anhydrous MgSO₄ in this research were of analytical grade or better and purchased from Shanghai Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China).