Mercury 400 mhz nmr

Manufactured by Agilent Technologies

Sourced in United States

The Mercury 400 MHz NMR is a nuclear magnetic resonance spectrometer designed for high-resolution analysis. It operates at a frequency of 400 MHz and is capable of performing various NMR spectroscopy techniques to identify and characterize chemical compounds.

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Lab products found in correlation

Thermo ltq orbitrap xl mass spectrometer, by Thermo Fisher Scientific (4 mentions) Daltonics data analysis 3.4 mass spectrometer, by Bruker (3 mentions) Methyl sulfoxide d6, by Thermo Fisher Scientific (1 mentions) Human apoptosis array kit, by R&D Systems (1 mentions) 600 mhz nmr, by Agilent Technologies (1 mentions) Sp 930 d, by Younglin (1 mentions)

5 protocols using mercury 400 mhz nmr

NMR Characterization of Electrolytes

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¹H NMR was performed on a Varian Mercury 400 MHz NMR. The temperature was set at 25°C. Samples were prepared in the glove box by injecting 300 μl of electrolyte into a new and dried NMR tube, together with 600 μl of methyl sulfoxide-d6 (Acros Organics, 99.9% D, maximum 0.03% water impurity). It was then sealed with polytetrafluoroethylene caps and immediately put into the NMR machine for data acquisition. The samples were locked and shimmed using the external standard.

Vilá R.A., Boyle D.T., Dai A., Zhang W., Sayavong P., Ye Y., Yang Y., Dionne J.A, & Cui Y. (2023). LiH formation and its impact on Li batteries revealed by cryogenic electron microscopy. Science Advances, 9(12), eadf3609.

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Comprehensive NMR and MS Characterization of Organic Compounds

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All solvents and reagents were obtained from commercial sources and used without further purification, and the solvents used were dried by conventional methods. ¹H and ¹³C NMR spectra were recorded on a Mercury 400 MHz NMR, Varian, Palo Alto, CA, USA and 600 MHz NMR. (CDCl₃ and DMSO-d₆ were the solvent and TMS was the internal standard). MS spectra were measured on Bruker Daltonics Data Analysis 3.4 Mass Spectrometer, Bruker, Karlsruhe, Germany and Thermo LTQ Orbitrap-XL Mass Spectrometer (Thermo Scientific, Waltham, MA, USA). Analytic HPLC analysis was performed on a YOUNG LIN instrument with a C-18 column (5 μm, 4.6 × 150 mm), SP930D solvent delivery pump, UV730D UV/VIS dual absorbance detector. HPLC analysis showed that the purity of all the final products were more than 96%. The column was eluted with acetonitrile at a flow rate of 0.5 mL/min. HSGF 254 high-efficiency thin-layer chromatography silica gel plates were purchased from Huiyou Development Co., Yantai, Shangdong, China. Ltd. HSGF 254 thin-layer silica gel (300 mesh–400 mesh) was purchased from Ocean Chemical Plant (Qingdao, Shangdong, China). Human Apoptosis Array Kit (ARY009) was bought from R&D Systems, Inc. (Minneapolis, USA).

Jia J., Yin H., Chen C., Hu M., Zhong Q., Zheng S., Zhang W., Li H., Xu L., Wang G, & He L. (2022). Design, synthesis, and evaluation of a novel series of mono-indolylbenzoquinones derivatives for the potential treatment of breast cancer. European journal of medicinal chemistry, 237, 114375.

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Optimized Synthesis and Characterization

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All solvents and reagents were obtained from commercial sources unless otherwise mentioned, and the solvents used were dried by conventional methods. All reactions were performed under a nitrogen atmosphere. The ¹H and ¹³C NMR spectra were recorded on a Mercury 400 MHz NMR, Varian, Palo Alto, CA, USA and 600 MHz NMR. (CDCl₃ and DMSO-d₆ were the solvent and TMS was the internal standard). MS spectra were measured on Bruker Daltonics Data Analysis 3.4 Mass Spectrometer, Bruker, Karlsruhe, Germany and Thermo LTQ Orbitrap-XL Mass Spectrometer (Thermo Scientific, Waltham, MA, USA). A YRT-3 melting point instrument (Tianda Tianfa Company, Tianjin, China) was used for measuring melting points. HSGF 254 high-efficiency thin-layer chromatography silica gel plates were purchased from Huiyou Development Co., Yantai, Shangdong, China. Ltd. HSGF 254 thin-layer silica gel (300 mesh–400 mesh) was purchased from Ocean Chemical Plant (Qingdao, Shangdong, China).

Luo L., Jia J.J., Zhong Q., Zhong X., Zheng S., Wang G, & He L. (2020). Synthesis and anticancer activity evaluation of naphthalene-substituted triazole spirodienones. European journal of medicinal chemistry, 213, 113039.

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Characterization of 1-oxa-4-azaspiro[4.5] Deca-6,9-diene-3,8-dione Derivatives

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NMR spectra were recorded on a Mercury 400 MHz NMR, Varian, Palo Alto, CA, USA and an 600 MHz NMR, Agilent Technologies Inc. Palo Alto, California, USA(CDCl3 was the solvent and TMS was the internal standard). MS spectra were measured on Bruker Daltonics Data Analysis 3.4 Mass Spectrometer, Bruker, Karlsruhe, Germany and Thermo LTQ Orbitrap-XL Mass Spectrometer (Thermo Scientific, Waltham, MA, USA). A YRT-3 melting point instrument (Tianda Tianfa Company, Tianjin, China) was used for measuring melting points, where the measured temperature was uncorrected. HSGF 254 high-efficiency thin-layer chromatography silica gel plates were purchased from Huiyou Development Co., Yantai, Shangdong, China. Ltd. HSGF 254 thin-layer silica gel (300 mesh ~ 400 mesh) was purchased from Ocean Chemical Plant (Qingdao, Shangdong, China). The reagents used were analytically pure unless otherwise specified, and the solvents used were dried by conventional methods. (NMR spectra (1H and 13C) of all 17 1-oxa-4-azaspiro[4.5] deca-6,9-diene-3,8-dione derivatives are provided in Supplementary Materials).

Yang Z., Zhong Q., Zheng S., Wang G, & He L. (2019). Synthesis and Antitumor Activity of a Series of Novel 1-Oxa-4-azaspiro[4,5]deca-6,9-diene-3,8-dione Derivatives. Molecules, 24(5), 936.

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Spectroscopic Characterization of Organic Compounds

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All reagents and solvents were obtained commercially unless otherwise mentioned. The solvents we used were dried by conventional methods. All reactions were performed with nitrogen protected. The ¹H and ¹³C NMR spectra were recorded on a Mercury 400 MHz NMR, Varian, Palo Alto, CA, USA and 600 MHz NMR. (CDCl₃ and DMSO-d₆ were used as the solvent and TMS was the internal standard). MS spectra were measured on Bruker Daltonics Data Analysis 3.4 Mass Spectrometer, Bruker, Karlsruhe, Germany and Thermo LTQ Orbitrap-XL Mass Spectrometer (Thermo Scientific, Waltham, MA, USA). HSGF 254 high-efficiency thin-layer chromatography silica gel plates were bought from Huiyou Development Co., Yantai, Shangdong, China. Ltd. HSGF 254 thin-layer silica gel (300 mesh to 400 mesh) was bought from Ocean Chemical Plant (Qingdao, Shangdong, China). Analytic HPLC analysis was performed on a YOUNG LIN instrument with a Luna C-18(2) 100A 4.6 × 250 mm 5 μm column, SP930D solvent delivery pump, UV730D UV/VIS dual absorbance detector. HPLC analysis showed that the purity of all the final products were >95%. The column was eluted with acetonitrile at a flow rate of 0.5 mL/min.

Chen C., Luo Y., Yin H., Zhong Q., Zheng S., Liu R., Zhao C., Wang G, & He L. (2022). Design, synthesis, and antitumor activity evaluation of novel acyl sulfonamide spirodienones. Bioorganic & medicinal chemistry, 60, 116626.

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