O coumaric

Acetonitrile (hypergrade for LC–MS), formic acid (for LC–MS) and methanol (analytical grade) were purchased from Merck (Merck, Bulgaria). The reference standards used for compound identification were obtained from Extrasynthese (Genay, France) for p-coumaric, o-coumaric, ferulic acids, saponarin, homoorientin, orientin, rutin, isovitexin, isoquercitrin, luteolin 7-O-glucoside, kaempferol 3-O-rutinoside, kaempferol 3-O-glucoside, isorhamnetin 3-O-glucoside, apigenin 7-O-glucoside, quercetin, and apigenin. Chlorogenic and caffeic acids were supplied from Phytolab (Vestenbergsgreuth, Bavaria, Germany).

Galantamine hydrobromide (Sopharma, Sofia, Bulgaria, Mw = 368.3 g/mol, purity > 98%); Ginkgo biloba capsules 80 mg (Adipharm, Sofia, Bulgaria, dry standardized leaf extract (EGb 761), contains 6% terpenolactones and 24% flavonoid glycosides).
Acetonitrile (hypergrade for LC-MS), formic acid (for LC-MS), and methanol (analytical grade) were purchased from Chromasolv (Sofia, Bulgaria). The reference standards used for compound identification were obtained from Extrasynthese (Genay, France) for protocatechuic, gentisic, p-coumaric, m-coumaric, o-coumaric, syringic, vanillic, and salicylic acids and hyperoside, luteolin 7-O-glucoside, isorhamnetin 3-O-glucoside, luteolin, quercetin, kaempferol, isorhamnetin, and jaceosidin. Neochlorogenic, chlorogenic, caffeic, 3,4-dicaffeoylquinic, 3,5-dicaffeoylquinic, and 1,5-dicaffeoylquinic acids were supplied from Phytolab (Vestenbergsgreuth, Germany).

Acetonitrile, formic acid (for LC–MS) and methanol (analytical grade) were provided from Merck (Merck, Sofia, Bulgaria). The reference standards, using for UHPLC-HRMS protocatechuic, p-coumaric, m-coumaric, o-coumaric, vanillic, gentisic and salicylic acids, luteolin 7-O-glucoside, kaempferol-3-O-rutinoside, kaempferol 3-O-glucoside, isorhamnetin 3-O-glucoside, nepetin 7-O-glucoside, hyperoside, apigenin, quercetin, kaempferol, hispidulin, chrysoeriol, isorhamnetin, jseocidine, and luteolin were obtained from Extrasynthese (Genay, France). Chlorogenic, neochlorogenic, caffeic, 3,4-dicaffeoylquinic, 3,5-dicaffeylquinic and 1,5-dicaffeoylquinic acids, as well as dehydrocostus lactone, isoalantolactone, alantolactone, and partenolide, were supplied from Phytolab (Vesten-Bergsgreuth, Germany).