Spss version 26.0 for windows 21

Statistical data were analyzed using IBM SPSS version 26.0 for windows 21 (IBM Corporation) and reported as n (%), mean ± standard deviation or median interquartile range as appropriate. Statistical analysis was performed using the Student's t‐test and Mann–Whitney U test for continuous variables, while the chi‐squared test and Fisher's exact test were used for categorical variables. Univariate and multiple regression model were conducted to analyze possible predictor factors for severe cerebral damage. p‐values < 0.05 were considered statistically significant for all variables.

Statistical analysis was performed using IBM SPSS version 26.0 for Windows21 (IBMCorp.). All parameters were converted to Z scores using previously published nomograms.¹², ¹³, ¹⁴, ¹⁵, ¹⁶, ¹⁷, ¹⁸ Continuous variables were expressed as mean ± standard deviation and categorical variables as absolute number (percentage). Biometric and Doppler parameters were compared using Student's t test to determine differences between two groups (CHD vs healthy ones). For multiple comparisons, one‐way analysis of variance was used. Dichotomous variables were analyzed using the chi‐squared test and Fisher's exact test. To analyze the longitudinal changes throughout gestation, a general linear model between–within subject analysis of variance test was performed. Significance was previously set at 95% level (p < 0.05).