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Metolose 90sh 100 000sr

Manufactured by Shin-Etsu Chemical
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Sourced in United Kingdom, Japan

Metolose 90SH-100,000SR is a methylcellulose-based viscosity modifier produced by Shin-Etsu Chemical. It is a white to yellowish-white, odorless, and tasteless powder. Metolose 90SH-100,000SR is soluble in cold water and forms a clear, viscous solution.

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Lab products found in correlation

90sh 4 000sr, by Shin-Etsu Chemical (1 mentions) Vivapur 12, by JRS Pharma (1 mentions) Aerosil r972, by Evonik (1 mentions) Lactose monohydrate, by Merck Group (1 mentions) Silicon dioxide, by Merck Group (1 mentions) Magnesium stearate st mg, by Merck Group (1 mentions)

2 protocols using metolose 90sh 100 000sr

1

Oxycodone Extended-Release Formulation

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The following materials were purchased from various companies and used as received: oxycodone hydrochloride (Macfarlan Smith, Edinburgh, Scotland); hydroxypropyl methylcellulose (HPMC; Metolose 90SH-100,000SR, 60SH-10,000SR, and 90SH-4,000SR; Shin-Etsu Chemical, Tokyo, Japan); hydroxypropyl cellulose (HPC; Klucel™-HF, Ashland, Covington, KY, USA); lactose monohydrate (FlowLac® 100; Molkerei MEGGLE Wasserburg GmbH & Co. KG, Wasserburg, Germany); microcrystalline cellulose (Vivapur 12®; JRS Pharma, Rosenberg, Germany); and fumed silica (Aerosil® R972; Evonik, Essen, Germany). All other chemicals used were of high-performance liquid chromatography (HPLC) or reagent grade.
Kim J.Y., Lee S.H., Park C.W., Rhee Y.S., Kim D.W., Park J., Lee M., Seo J.W, & Park E.S. (2015). Design and in vivo evaluation of oxycodone once-a-day controlled-release tablets. Drug Design, Development and Therapy, 9, 695-706.
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2

Formulation and Characterization of Metformin and Dapagliflozin Tablets

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Metformin HCl and dapagliflozin l-proline were supplied by Kyung-dong Pharm (Seoul, Korea). Hydroxypropyl methylcellulose (Metolose® 90 SH 100,000 SR) and low-substituted hydroxypropyl cellulose (L-HPC) were purchased from Shin-Etsu Chemical Co., Ltd. (Tokyo, Japan). Lactose monohydrate, magnesium stearate (St–Mg), and silicon dioxide were purchased from Sigma-Aldrich Co. (St. Louis, MO, USA). Microcrystalline cellulose (MCC 101) was purchased from DFE Pharma (Goch, Nordrhein-Westfalen, Germany). Calcium silicate was purchased from Fluka (Buchs, St. Gallen, Switzerland). All other reagents used were of analytical or HPLC grade.
Chun M.H., Kim J.Y., Park E.S, & Choi D.H. (2021). Development of a Robust Control Strategy for Fixed-Dose Combination Bilayer Tablets with Integrated Quality by Design, Statistical, and Process Analytical Technology Approach. Pharmaceutics, 13(9), 1443.
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