Log In Sign up
The largest database of trusted experimental protocols

Jaki azd1480

Manufactured by Selleck Chemicals
Visit Supplier

JAKi AZD1480 is a selective and potent Janus kinase (JAK) inhibitor. It primarily targets the JAK1 and JAK2 isoforms. JAKi AZD1480 is designed for use in research applications.

Automatically generated - may contain errors

Lab products found in correlation

Flag tag (flag), by Merck Group (2 mentions) V5 tag, by Thermo Fisher Scientific (2 mentions) Rnf125, by Thermo Fisher Scientific (2 mentions) β actin, by Santa Cruz Biotechnology (2 mentions) Brafi plx4032, by Selleck Chemicals (2 mentions) Egfri gefitinib zd1839, by Selleck Chemicals (2 mentions) Jaki pyridone 6, by Merck Group (2 mentions) Stat3, by Santa Cruz Biotechnology (2 mentions)

Spelling variants of this product

AZD1480 (52 citations)

2 protocols using jaki azd1480

1

Molecular Signaling Pathways Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
The BRAFi PLX4032, the EGFRi gefitinib/ZD1839, and the JAKi AZD1480 were purchased from Selleckchem. The JAKi pyridone 6 was purchased from Millipore. The following antibodies were used: FLAG-tag from Sigma-Aldrich; V5-tag from Life Technology or Bethyl Laboratories; Stat3, β-actin, GFP, and control IgG from Santa Cruz; TYK2 from BD Biosciences; JAK2, JAK3, EGFR, AXL, pStat3, and DDX58/RIG-I from Cell Signaling; GAS6 from R&D Systems; RNF125 from Life Technology, Bethyl Laboratories, AbCam, or Sigma-Aldrich; and JAK1 from Santa Cruz, BD Biosciences, Cell Signaling, or EMD Millipore.
Kim H., Frederick D.T., Levesque M.P., Cooper Z.A., Feng Y., Krepler C., Brill L., Samuels Y., Hayward N.K., Perlina A., Piris A., Zhang T., Halaban R., Herlyn M.M., Brown K.M., Wargo J.A., Dummer R., Flaherty K.T, & Ronai Z.A. (2015). Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. Cell reports, 11(9), 1458-1473.
+ Open protocol
+ Expand
2

Molecular Signaling Pathways Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
The BRAFi PLX4032, the EGFRi gefitinib/ZD1839, and the JAKi AZD1480 were purchased from Selleckchem. The JAKi pyridone 6 was purchased from Millipore. The following antibodies were used: FLAG-tag from Sigma-Aldrich; V5-tag from Life Technology or Bethyl Laboratories; Stat3, β-actin, GFP, and control IgG from Santa Cruz; TYK2 from BD Biosciences; JAK2, JAK3, EGFR, AXL, pStat3, and DDX58/RIG-I from Cell Signaling; GAS6 from R&D Systems; RNF125 from Life Technology, Bethyl Laboratories, AbCam, or Sigma-Aldrich; and JAK1 from Santa Cruz, BD Biosciences, Cell Signaling, or EMD Millipore.
Kim H., Frederick D.T., Levesque M.P., Cooper Z.A., Feng Y., Krepler C., Brill L., Samuels Y., Hayward N.K., Perlina A., Piris A., Zhang T., Halaban R., Herlyn M.M., Brown K.M., Wargo J.A., Dummer R., Flaherty K.T, & Ronai Z.A. (2015). Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. Cell reports, 11(9), 1458-1473.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!