Balb c h 2kd

Manufactured by Charles River Laboratories

Sourced in Japan

BALB/c (H-2Kd) is a mouse strain that expresses the H-2Kd major histocompatibility complex (MHC) class I allele. It is a commonly used laboratory mouse model.

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Lab products found in correlation

B6 cg tg actflpe 9205dym j, by Jackson ImmunoResearch (1 mentions) B6 cg tg vil cre 1000gum j mice, by Jackson ImmunoResearch (1 mentions) B6.129s7 rag1tm1mom j, by Jackson ImmunoResearch (1 mentions)

3 protocols using balb c h 2kd

BALB/c and C57BL/6 Mouse Housing

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BALB/c (H-2K^d) and C57BL/6 (H-2K^b) female mice of 6–7 weeks of age and weighing 19–21 g were obtained from Charles River Laboratories (Yokohama, Japan). The mice were kept under specific pathogen-free conditions with a 12 hour light: 12 hour dark cycle and free access to food and water, and received humane care in compliance with Institutional Guidelines. All experiments were approved by the Animal Care and Use Committee of Sapporo Medical University.

Hashimoto A., Sato T., Iyama S., Yoshida M., Ibata S., Tatekoshi A., Kamihara Y., Horiguchi H., Murase K., Kawano Y., Takada K., Miyanishi K., Kobune M., Ichimiya S, & Kato J. (2016). Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells. PLoS ONE, 11(3), e0152823.

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Generation of Conditional Sdha Knockout Mice

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C57BL/6 (WT B6, H-2K^b, CD45.2), B6 Ly5.2 (H-2K^b, CD45.1), B6.129S7-Rag1^tm1Mom/J(Rag-1^−/−), Sdhaf1^−/−, B6.Cg-Tg(ACTFLPe)9205Dym/J, B6.Cg-Tg(Vil-cre)1000Gum/J mice, C3H.SW (H-2K^b, CD229.1), and C57BL/6N-Acod1em1(IMPC)J/J (Irg1^−/−) mice were purchased from the Jackson Laboratory (Bar Harbor, ME, USA). BALB/c (H-2K^d) and BDF1 (H-2K^b/d) mice were purchased from Charles River Laboratories. C57BL/6N-Sdha^{tm2a(KOMP)Wtsi} mice were obtained from Knock Out Mouse Project (KOMP) repository, University of California, Davis and bred to ACTFLPe mice to excise the FRT-flanked region (Extended Data Figure 6g). Then Sdha^fl/fl mice were bred to Vil1-Cre mice to create Vil1-Cre Sdha^fl/fl (Sdha^Δ/IEC) mice. 8–12 weeks old female mice used for experiments. All mice were kept under specific pathogen-free (SPF) conditions and cared for according to regulations reviewed and approved by the University of Michigan Committee on the Use and Care of Animals (PRO00009494), which are based on the University of Michigan Laboratory Animal Medicine guidelines

Fujiwara H., Seike K., Brooks M.D., Mathew A.V., Kovalenko I., Pal A., Lee H.J., Peltier D., Kim S., Liu C., Oravecz-Wilson K., Li L., Sun Y., Byun J., Maeda Y., Wicha M.S., Saunders T., Rehemtulla A., Lyssiotis C.A., Pennathur S, & Reddy P. (2021). Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology. Nature immunology, 22(11), 1440-1451.

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Mouse Strain Comparison Protocol

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BALB/c (H2-K d ) and C57BL/6 (B6, H2-K b ) mice were purchased from Charles River (Frederick, MD). Animals were housed in specific pathogen-free conditions and experiments conducted in accordance with National Institutes of Health guidelines, and with approval by the JHU Animal Care and Use Committee.

Iglesias M., Khalifian S., Oh B.C., Zhang Y., Miller D., Beck S.E., Brandacher G., & Raimondi G. (2020). A short course of Tofacitinib sustains the immunoregulatory effect of CTLA4-Ig in presence of inflammatory cytokines and promotes long-term survival of murine cardiac allografts.

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