Log In Sign up
The largest database of trusted experimental protocols

Affymetrix 6.0 snp array in whi

Manufactured by Thermo Fisher Scientific
Visit Supplier

The Affymetrix 6.0 SNP Array is a laboratory equipment product designed for genetic analysis. It is used to detect single nucleotide polymorphisms (SNPs) across the human genome. The core function of this array is to provide a platform for high-throughput genotyping of genetic variants.

Automatically generated - may contain errors

Lab products found in correlation

Spelling variants of this product

SNP 6.0 arrays (95 citations) 6.0 array (32 citations) SNP 6.0 (30 citations) SNP Array 6.0 (27 citations) Affymetrix 6.0 array (7 citations) SNP arrays (4 citations) Array 6.0 (2 citations)

2 protocols using affymetrix 6.0 snp array in whi

1

FTO Genetic Variants and BMI Associations

Cited 4 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
We used a common variant, rs9939609 (A/T) repeatedly identified in many BMI GWAS in EA and AA 27 (link)–29 (link). Given the lack of association of the rs9939609 SNP in some studies of AA 30 (link), we also considered other SNPs identified in fine-mapping efforts in AA: rs1421085, rs56137030, rs17817964, and rs8050136 31 (link),32 (link). Genotyping was originally performed using the Affymetrix 500 SNP Array in FHS, and the Affymetrix 6.0 SNP Array in WHI (Affymetrix Inc, Santa Clara, CA). In WHI the DNA was extracted from blood samples collected at enrollment, and genotyping QC included concordance rates for blinded and unblended duplicates 33 (link). In order to test multiple FTO SNPs in WHI, we used imputed genotypes which were available in dbGaP. Briefly, genotypes were imputed using BEAGLE software 34 (link), and 1,000 Genomes data 35 (link) as reference. Individuals with missing values of FTO genotypes were excluded from all analyses.
Klimentidis Y.C., Arora A., Chougule A., Zhou J, & Raichlen D. (2015). FTO association and interaction with time spent sitting. International journal of obesity (2005), 40(3), 411-416.
+ Open protocol
+ Expand
2

FTO Genetic Variants and BMI Associations

Cited 4 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
We used a common variant, rs9939609 (A/T) repeatedly identified in many BMI GWAS in EA and AA 27 (link)–29 (link). Given the lack of association of the rs9939609 SNP in some studies of AA 30 (link), we also considered other SNPs identified in fine-mapping efforts in AA: rs1421085, rs56137030, rs17817964, and rs8050136 31 (link),32 (link). Genotyping was originally performed using the Affymetrix 500 SNP Array in FHS, and the Affymetrix 6.0 SNP Array in WHI (Affymetrix Inc, Santa Clara, CA). In WHI the DNA was extracted from blood samples collected at enrollment, and genotyping QC included concordance rates for blinded and unblended duplicates 33 (link). In order to test multiple FTO SNPs in WHI, we used imputed genotypes which were available in dbGaP. Briefly, genotypes were imputed using BEAGLE software 34 (link), and 1,000 Genomes data 35 (link) as reference. Individuals with missing values of FTO genotypes were excluded from all analyses.
Klimentidis Y.C., Arora A., Chougule A., Zhou J, & Raichlen D. (2015). FTO association and interaction with time spent sitting. International journal of obesity (2005), 40(3), 411-416.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!