2 deoxyguanosine 5 monophosphate

Manufactured by Merck Group

2'-deoxyguanosine-5'-monophosphate is a nucleotide compound used in biochemical research applications. It is the monophosphate form of the nucleoside 2'-deoxyguanosine.

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Lab products found in correlation

2 deoxycytidine 5 monophosphate, by Merck Group (3 mentions) 2 deoxyadenosine 5 monophopshate, by Merck Group (2 mentions) 2 deoxythmidine 5 monophosphate, by Merck Group (2 mentions) 1n hydrochloric acid, by Merck Group (2 mentions) 1n sodium hydroxide, by Merck Group (1 mentions) Sodium chloride (nacl), by Merck Group (1 mentions) Deoxyribonucleic acid sodium salt, by Merck Group (1 mentions) 3 4 5 dimethylthiazol 2 yl 2 5 diphenyltetrazolium bromide mtt, by Merck Group (1 mentions) 2 deoxyadenosine 5 monophosphate, by Merck Group (1 mentions) 9 10 anthracenediyl bis methylene dimalonic acid abda, by Merck Group (1 mentions) Zetasizer nano, by Malvern Panalytical (1 mentions) Sodium hydroxide (naoh), by Merck Group (1 mentions)

3 protocols using 2 deoxyguanosine 5 monophosphate

Nucleotide Synthesis and Characterization

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2′-deoxycytidine-5′-monophosphate
(dCMP), 2′-deoxyguanosine-5′-monophosphate (dGMP), 2′-deoxyadenosine-5′-monophopshate
(dAMP), 2′-deoxythmidine-5′-monophosphate (dTMP), sodium
chloride, 1N hydrochloric acid, and 1N sodium hydroxide were purchased
from Sigma-Aldrich. Anatase TiO₂ particles were purchased
from US Research Nanomaterials stock number #US3498. All chemicals
were used without additional modification or purification. For clarity,
nucleotides have three main functional groups, the nitrogenous ring,
the ribose sugar ring, and the phosphate group. The nitrogenous ring
and ribose are defined as the nucleosides. The nucleoside with the
phosphate group is the nucleotide.

Sit I., Quirk E., Hettiarachchi E, & Grassian V.H. (2022). Differential Surface Interactions and Surface Templating of Nucleotides (dGMP, dCMP, dAMP, and dTMP) on Oxide Particle Surfaces. Langmuir, 38(49), 15038-15049.

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Analyzing Nucleic Acid Components

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Adenine, guanine, cytosine, thymine, adenosine, 2′-deoxyadenosine 5′-monophosphate, 2′-deoxyguanosine 5′-monophosphate, 2′-deoxycytidine 5′-monophosphate, 2′-deoxythymidine 5′-monophosphate, adenosine 5′-diphosphate, deoxyadenosine 5′-triphosphate, deoxyribonucleic acid sodium salt from salmon testes (approximately 2000 bp), 9,10-anthracenediyl-bis(methylene)dimalonic acid (ABDA) and 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) were purchased from Sigma-Aldrich. Deionized (DI) water with a specific resistance of 18.2 MΩ was used.

Zheng X.T., Lai Y.C, & Tan Y.N. (2019). Nucleotide-derived theranostic nanodots with intrinsic fluorescence and singlet oxygen generation for bioimaging and photodynamic therapy. Nanoscale Advances, 1(6), 2250-2257.

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Nucleotide Zeta Potential Measurement

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2′-deoxyadenosine-5′-monophopshate (dAMP), 2′-deoxyguanosine-5′-monophosphate (dGMP), 2′-deoxycytidine-5′-monophosphate (dCMP), 2′-deoxythmidine-5′-monophosphate (dTMP), sodium chloride, 1N hydrochloric acid, and 1N sodium hydroxide were purchase from Sigma-Aldrich (where 1N means 1 normal concentrations of these solutions). Hematite and goethite particles were purchased from Alfa Aesar, MA. Zeta potential measurements of nucleotides at pH 5 were performed with the Zetasizer Nano from Malvern Instruments. Triplicate measurements are reported with 1σ standard deviation for the indicated error.

Sit I., Young M.A., Kubicki J.D, & Grassian V.H. (2023). Distinguishing different surface interactions for nucleotides adsorbed onto hematite and goethite particle surfaces through ATR-FTIR spectroscopy and DFT calculations. Physical Chemistry Chemical Physics, 25(30), 20557-20566.

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