Tempol, apocynin, db-cAMP, SQ22536, vigabatrin, gabazine, yohimbine and clonidine were obtained from MedChemExpress (Monmouth Junction, NJ, USA). LPS, CGP35348, DEX and DETC were purchased from Sigma (St Louis, MO, USA). Rp-cAMP was purchased from Beyotime (Shanghai, China). apocynin and CGP35348 were dissolved in PBS containing 1% DMSO and the vehicle was used as a control. Other chemicals were dissolved in PBS. PBS was used as a control.
Yohimbine
Manufactured by MedChemExpress
Sourced in United States
Yohimbine is a chemical compound commonly used in laboratory research. It is a naturally occurring indole alkaloid that can be extracted from the bark of the Pausinystalia yohimbe tree. Yohimbine is known for its physiological effects and is often utilized in scientific investigations, though its specific applications may vary depending on the research context.
Automatically generated - may contain errors
Lab products found in correlation
Dexamethasone (dex), by Merck Group (1 mentions)
Lipopolysaccharides (lps), by Merck Group (1 mentions)
Sq22536, by MedChemExpress (1 mentions)
Vigabatrin, by MedChemExpress (1 mentions)
Db camp, by MedChemExpress (1 mentions)
Apocynin, by MedChemExpress (1 mentions)
Cgp35348, by Merck Group (1 mentions)
Tempol, by MedChemExpress (1 mentions)
Lidocaine, by MedChemExpress (1 mentions)
Forskolin, by MedChemExpress (1 mentions)
Prazosin, by MedChemExpress (1 mentions)
Zd7288, by Merck Group (1 mentions)
2 protocols using yohimbine
1
Characterizing Neuroinflammatory Modulators
2
Pharmacological Investigation of Ion Channels
Check if the same lab product or an alternative is used in the 5 most similar protocols
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We purchased lidocaine, dexmedetomidine, prazosin, yohimbine, and forskolin from MedChemExpress (Shanghai, China) and ZD7288 from Sigma‒Aldrich (Shanghai, China). lidocaine hydrochloride 2% (w/v) was prepared in 0.9% NaCl solution. Dexmedetomidine hydrochloride was diluted in 2% lidocaine solution to final concentrations of 6.8, 13.6, and 20.4 μM (approximately 3, 6, and 9 μg/kg). The α1 antagonist prazosin (1.3 mM, ~1 mg/kg) and α2 antagonist yohimbine (1.6 mM, ~1 mg/kg) were prepared in lidocaine. The HCN inhibitor ZD7288 (2.2 mM, ~1.14 mg/kg) and HCN activator forskolin (153.6 μM, ~110.9 μg/kg) were dissolved in 1% DMSO saline and then diluted in 2% lidocaine. All drug solutions were freshly prepared before the experiments.12 (link)
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