Log In Sign up
The largest database of trusted experimental protocols

Profinder v8

Manufactured by Agilent Technologies
Visit Supplier

Profinder v8.00 is a software application developed by Agilent Technologies for the analysis and processing of data from mass spectrometry experiments. The core function of Profinder v8.00 is to facilitate the identification and quantification of small molecules, peptides, and proteins in complex biological samples.

Automatically generated - may contain errors

Lab products found in correlation

Massprofiler pro, by Agilent Technologies (1 mentions)

3 protocols using profinder v8

1

Metabolite Identification and Normalization

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
Metabolites were identified by matching the retention time and mass (±10 ppm) to authentic standards. Peak areas were integrated using Profinder v8.00 (Agilent Technologies, Santa Clara, California). Data were normalized to urine creatinine levels and Loess drift correction, using Metabodrift 1.0 (Thonusin et al., 2017 (link)) and applied using the area of each metabolite in the control samples (pools) for correction.
Greco P.S., Hesson A.M., Mozurkewich E, & Berman D.R. (2022). Urinary metabolites as a predictive marker for perinatal depression: A secondary analysis of the mothers, Omega-3 & Mental Health Study. Psychiatry research communications, 2(2), 100046.
+ Open protocol
+ Expand
2

Metabolite Identification and Normalization

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
Metabolites were identified by matching the retention time and mass (±10 ppm) to authentic standards. Peak areas were integrated using Profinder v8.00 (Agilent Technologies, Santa Clara, California). Data were normalized to urine creatinine levels and Loess drift correction, using Metabodrift 1.0 (Thonusin et al., 2017 (link)) and applied using the area of each metabolite in the control samples (pools) for correction.
Greco P.S., Hesson A.M., Mozurkewich E, & Berman D.R. (2022). Urinary metabolites as a predictive marker for perinatal depression: A secondary analysis of the mothers, Omega-3 & Mental Health Study. Psychiatry research communications, 2(2), 100046.
+ Open protocol
+ Expand
3

Hybrid Targeted-Nontargeted Metabolite Analysis

Check if the same lab product or an alternative is used in the 5 most similar protocols
Identification of chromatographic peaks that represent features for this platform followed a hybrid targeted/non-targeted approach. Semi-quantitative data for known compounds was obtained by manual integration using Profinder v8.00 (Agilent Technologies, Santa Clara, CA). Metabolites were identified by matching the retention time (+/− 0.1 min), mass (+/− 10 ppm) and isotope profile (peak height and spacing) to authentic standards. Non-targeted data detection was performed using Agilent’s MassHunter Find by Molecular Feature workflow (v7.0) with recursion using Agilent’s Mass Profiler Pro (v8.0).
Kaul M, & Lipton S.A. (1999). Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 96(14), 8212-8216.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!