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1300a system

Manufactured by Aurora Scientific
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The 1300A system is a versatile laboratory equipment designed for a range of scientific applications. It features advanced capabilities that enable precise measurements and data analysis. The core function of the 1300A system is to provide reliable and consistent performance for researchers and scientists in various fields.

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1300A 3-in-1 Whole Animal System (11 citations) 1300A Whole Animal System (7 citations) In Vivo Muscle Test system 1300A (2 citations) Aurora 1300A: 3-in-1 Whole Animal System (2 citations)

2 protocols using 1300a system

1

In Vivo Mouse Muscle Force Measurement

Check if the same lab product or an alternative is used in the 5 most similar protocols
Male mice were anaesthetized using 4%–5% isoflurane and then ~2% isoflurane via a nosecone for maintenance, (both with 1-1.5L/min 100% O2). Rymadil (5mg/kg) was administered before starting the procedure. Briefly, the mouse was kept supine on a heated limb platform with clamps for affixing the limb. The leg was secured bent in a L shape in the limb plate using a sharpened screw positioned at the level of the knee. The foot was placed in the footplate, orthogonal to the tibia. Using a transcutaneous electrode, TA muscle was stimulated and force during plantarflexion was recorded (1300A system, Aurora Scientific Inc.). An in vivo stimulation protocol of a twitch (initial delay 0.2 s, pulse width 0.2ms) followed by a tetanus (initial delay 0.2 s, pulse frequency 65 Hz, pulse width 0.2ms, duration 0.8 s) repeated 3 times with a 60 s rest interval was applied.
Debattisti V., Horn A., Singh R., Seifert E.L., Hogarth M.W., Mazala D.A., Huang K.T., Horvath R., Jaiswal J.K, & Hajnóczky G. (2019). Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1. Cell reports, 29(5), 1274-1286.e6.
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2

In Vivo Mouse Muscle Force Measurement

Check if the same lab product or an alternative is used in the 5 most similar protocols
Male mice were anaesthetized using 4%–5% isoflurane and then ~2% isoflurane via a nosecone for maintenance, (both with 1-1.5L/min 100% O2). Rymadil (5mg/kg) was administered before starting the procedure. Briefly, the mouse was kept supine on a heated limb platform with clamps for affixing the limb. The leg was secured bent in a L shape in the limb plate using a sharpened screw positioned at the level of the knee. The foot was placed in the footplate, orthogonal to the tibia. Using a transcutaneous electrode, TA muscle was stimulated and force during plantarflexion was recorded (1300A system, Aurora Scientific Inc.). An in vivo stimulation protocol of a twitch (initial delay 0.2 s, pulse width 0.2ms) followed by a tetanus (initial delay 0.2 s, pulse frequency 65 Hz, pulse width 0.2ms, duration 0.8 s) repeated 3 times with a 60 s rest interval was applied.
Debattisti V., Horn A., Singh R., Seifert E.L., Hogarth M.W., Mazala D.A., Huang K.T., Horvath R., Jaiswal J.K, & Hajnóczky G. (2019). Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1. Cell reports, 29(5), 1274-1286.e6.
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