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Recombinant murine amphiregulin

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Recombinant murine Amphiregulin is a purified protein produced in a mammalian expression system. Amphiregulin is a member of the epidermal growth factor (EGF) family and functions as a growth factor.

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Lab products found in correlation

Recombinant murine il 33, by BioLegend (1 mentions) Recombinant murine il 10, by Thermo Fisher Scientific (1 mentions)

2 protocols using recombinant murine amphiregulin

1

Murine Amphiregulin treatment for Influenza

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Recombinant murine Amphiregulin (R&D Systems) was administrated by intraperitoneal injection. Each dose of 5 μg was used every two days starting from influenza virus infection at day 0. Virus-infected WT and cKO mice treated with PBS were used as control group.
Wu X., Kasmani M.Y., Zheng S., Khatun A., Chen Y., Winkler W., Zander R., Burns R., Taparowsky E.J., Sun J, & Cui W. (2022). BATF Promotes Group 2 Innate Lymphoid Cell-Mediated Lung Tissue Protection During Acute Respiratory Virus Infection. Science immunology, 7(67), eabc9934.
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2

Cytokine Delivery Protocol for Murine Studies

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For IL-33 treatment, anesthetized mice were injected intramuscular (i.m.) with 300ng/tibialis anterior (TA) (3μl) of recombinant murine IL-33 (Biolegend) followed by 2μg/mouse intraperitoneal (i.p.) (200μl) every other day thereafter until time of analysis. For IL-10 treatment, anesthetized mice were injected i.m. with 500ng/TA (3μl) of recombinant murine IL-10 (Peprotech) and 1μg/mouse i.p. (200μl) every other day thereafter until time of analysis. For amphiregulin treatment, anesthetized mice were injected i.m. with 1μg/TA (3μl) of recombinant murine amphiregulin (R&D Systems) and 7μg/mouse i.p. (200μl) every other day thereafter until time of analysis. Control mice were injected with PBS.
Jin R.M., Warunek J, & Wohlfert E.A. (2018). Therapeutic administration of IL-10 and amphiregulin alleviates chronic skeletal muscle inflammation and damage induced by infection. ImmunoHorizons, 2(5), 142-154.
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