The largest database of trusted experimental protocols

Precirol ato5

Manufactured by Merck Group
Sourced in Italy, Germany, France, United States

Precirol® ATO5 is a lipid excipient used in the formulation of pharmaceutical products. It is a mixture of glycerides primarily composed of palmitic and stearic acid esters. Precirol® ATO5 is used as a binder, disintegrant, and lubricant in solid dosage forms.

Automatically generated - may contain errors

5 protocols using precirol ato5

1

Cyclodextrin-Based Formulations for Hydrochlorothiazide

Check if the same lab product or an alternative is used in the 5 most similar protocols
Hydrochlorothiazide (HCT) was kindly supplied by Menarini (L’Aquila, Italy). Hydroxypropyl-β-cyclodextrin (Kleptose®HP, HPβCD average substitution degree DS = 0.85) and β-cyclodextrin were a gift from Roquette (Lestrem, France) and Sulfobutylether-β-cyclodextrin (Captisol®, SBEβCD) from Ligand Pharmaceuticals, Inc. (San Diego, CA, USA). Precirol®ATO5 (Glyceryldistearate NF/glycerylpalmitostearate), was kindly provided by Gattefossé (Milan, Italy); polyoxyethylene (Tween®80) was from Merck (Hohenbrunn, Germany), Poloxamer 188 (Pluronic®F68) from BASF (Ludwigshafen, Germany) and castor oil from Galeno (Prato, Italy). Purified water was obtained by reverse osmosis (Elix® Millipore, Baltimore, MD, USA). All other chemicals were of analytical grade.
+ Open protocol
+ Expand
2

Ciprofloxacin Hydrochloride Nanoparticle Formulation

Check if the same lab product or an alternative is used in the 5 most similar protocols
Ciprofloxacin hydrochloride was obtained from Hangzhou Dayang Chem. Co., Ltd. (Hangzhou, China), Polysorbate ® 80 (Merck, Darmstadt, Germany), while Precirol ® ATO 5 and Transcutol ® HP were donated by Gattefossé (Saint-Priest, France). Phospholipon ® 90G (P90G) was a gift from Phospholipid GmbH (Cologne, Germany) whereas Poloxamer ® 188 and Solutol ® HS (BASF, Ludwigshafen, Germany) were received as donations. Tallow fat was obtained from a batch processed in the Department of Pharmaceutics, University of Nigeria Nsukka (UNN). The biorelevant media, SGF (pH 1.2) and SIF (pH 6.8) were prepared without pepsin and pancreatin, respectively. Stock cultures of Bacillus subtilis were obtained from the Pharmaceutical Microbiology Unit of Department of Pharmaceutics, UNN. Distilled water was used throughout the study.
+ Open protocol
+ Expand
3

Sorafenib and Ganoderic Acid Formulation

Check if the same lab product or an alternative is used in the 5 most similar protocols
Sorafenib (free base) was purchased from Active Biochem, Billion Centre, Hong Kong. Ganoderic Acid (GA) was received from Sigma Aldrich, USA. Capmul MCM C10 and Capmul PG8 were purchased from M/s Gattefosse, Cedex, France. Precirol® ATO5 and Solutol HS15 were purchased from Sigma-Aldrich Inc., Alabama, USA. Solvents with HPLC grades were purchased from local vendors. Span Diagnostics, Surat, India, supplied the kits for detection of the serum sickness Alkaline Phosphatase Test (APT), albumin, Aspartate Transaminase (AST) Test, Alanine transferase (ALT) and total protein.
+ Open protocol
+ Expand
4

Fluoxetine Hydrochloride Formulation Development

Check if the same lab product or an alternative is used in the 5 most similar protocols
Fluoxetine hydrochloride was purchased from Jinlan Pharm-Drugs Technology Co., Limited (Hangzhou, China). Polysorbate 80 (Tween® 80) was acquired from Sigma Aldrich, Co. (St. Louis, MO, USA), while Precirol® ATO 5 (glyceryl palmitostearate, melting point: 53-56 °C), Capryol™ PGMC [Propylene glycol monocaprylate (type I) NF], Lauroglycol TM 90 and Transcutol® HP, were kindly donated by Gattefossé (Saint-Priest, Cedex, France). Cell culture media and supplements were obtained from Gibco (ThermoFisher Scientific, UK). Water was purified (Millipore) and filtered through a 0.22 μm nylon filter before use. All other reagents and solvents were from analytical or high performance liquid chromatography (HPLC) grade.
+ Open protocol
+ Expand
5

Posaconazole-Loaded Hemp Seed Oil Formulation

Check if the same lab product or an alternative is used in the 5 most similar protocols
Posaconazole was purchased from TCI Chemicals
and the extracted hemp seed oil was obtained as a gift sample from
Kumaokhand AIH Pvt., Ltd. Transcutol HP, PLGA, Tween 80, Precirol
ATO 5, and poloxamer 188 were purchased from Sigma-Aldrich. The experiment
was conducted using high-grade chemicals for HPLC.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!