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Ifnγr b6.129s7ifngr j

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The IFNγR−/− (B6.129S7Ifngr/J) is a strain of genetically modified mice. These mice have a targeted disruption in the interferon gamma receptor (IFNγR) gene, resulting in the absence of a functional IFNγ receptor. This strain is commonly used in research to study the role of IFNγ signaling in various biological processes.

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Lab products found in correlation

C57bl 6j, by Jackson ImmunoResearch (3 mentions) Inos b6.129p2 nos2tm1lau j, by Jackson ImmunoResearch (2 mentions) Balb c, by Jackson ImmunoResearch (2 mentions) Inos b6.129p2 nos2tm1lau j mice, by Jackson ImmunoResearch (1 mentions) B6.129p2 il4tm1cgn j, by Jackson ImmunoResearch (1 mentions)

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IFNγR−/− (8 citations)

3 protocols using ifnγr b6.129s7ifngr j

1

Mouse Strain Breeding and Handling

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Two-to-four month old male and female mice, bred and maintained at Rider University, were handled in accord with NIH, Animal Welfare Act, and Rider University IACUC guidelines. Breeding pairs of C57BL/6J, IFNγR−/− (B6.129S7Ifngr/J), and iNOS−/− (B6.129P2-Nos2tm1Lau/J) mice were obtained from the Jackson Laboratory, Bar Harbor, ME. PD-L1−/− mice initially came from the laboratory of Dr. Arlene Sharpe, Harvard Medical School, Cambridge, MA.
Goldman N., Lomakova Y.D., Londregan J., Bucknum A., DePierri K., Somerville J, & Riggs J.E. (2017). High macrophage PD-L1 expression not responsible for T cell suppression. Cellular immunology, 324, 50-58.
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2

Mouse Breeding and Maintenance Protocols

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Two to four month old male and female mice, bred and maintained at Rider University, were handled in accord with NIH, Animal Welfare Act, and Rider University IACUC guidelines. Breeding pairs of C57BL/6J, BALB/c, CB17-Prkdcscid/J, IFNγR−/− (B6.129S7Ifngr/J), iNOS−/− (B6.129P2-Nos2tm1Lau/J), and IL4−/− (B6.129P2-IL4tm1Cgn/J) mice were obtained from the Jackson Laboratory, Bar Harbor, ME.
Goldman N., Valiuskyte K., Londregan J., Swider A., Somerville J, & Riggs J.E. (2017). Macrophage regulation of B cell proliferation. Cellular immunology, 314, 54-62.
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3

Breeding and Handling of Mouse Strains

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Two to four month old male and female mice, bred and maintained at Rider University, were handled in accord with NIH, Animal Welfare Act, and Rider University IACUC guidelines. Breeding pairs of C57BL/6J, BALB/c, IFNγR−/− (B6.129S7Ifngr/J), and iNOS−/− (B6.129P2-Nos2tm1Lau/J) mice were obtained from the Jackson Laboratory, Bar Harbor, ME.
Wood M.A., Goldman N., DePierri K., Somerville J, & Riggs J.E. (2016). Erythropoietin increases macrophage-mediated T cell suppression. Cellular immunology, 306-307, 17-24.
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