Mebendazole was a gift sample from the Iraqi Pharmaceutical Industry (IPI) Company (Baghdad, Iraq). Polyethylene glycol 6000 was purchased from Merck Schuchardt -Germany, AC-DI-SOL AE Crosscarmelose from FMC Biopolymers, and Ludiflash from BASF. HPLC gradient grade ace-tonitrile and methanol were purchased from Merck KGaA (Darmstadt, Germany), whereas HPLC grade methyl tert-butyl ether was acquired from Sigma-Aldrich (Taufkirchen, Germany). HPLC grade trifluoroacetic acid was obtained from Honeywell-Fluka (Buchs, Switzerland). Physiological compounds -granular Lecithin, (Acros Organics, Geel, Belgium) and sodium taurocholate min 98% (Carl Roth, Karlsruhe, Germany) were used in the preparation of the simulated intestinal fluids. Ultrapure water (resistivity 18.2 MΩ ∑ cm at 25 O C, TOC < 5ppb) was obtained from a Milli-Q (Millipore, Milford, MA, USA) water purification system. All other reagents were of analytical grade, purchased from different commercial suppliers, and used without further purification.
Granular lecithin
Manufactured by Thermo Fisher Scientific
Sourced in Belgium, United Kingdom
Granular Lecithin is a functional food ingredient derived from soybeans. It is a naturally occurring phospholipid that acts as an emulsifier, dispersant, and lubricant in various food and non-food applications.
Automatically generated - may contain errors
Lab products found in correlation
Hplc gradient grade acetonitrile, by Merck Group (1 mentions)
Hplc grade methyl tert butyl ether, by Merck Group (1 mentions)
Milli q, by Merck Group (1 mentions)
Ludiflash, by BASF (1 mentions)
Methanol, by Merck Group (1 mentions)
Polyethylene glycol 6000, by Merck Group (1 mentions)
Sodium dodecyl sulphate (sds), by Avantor (1 mentions)
Polysorbate 80, by Thermo Fisher Scientific (1 mentions)
L histidine, by Thermo Fisher Scientific (1 mentions)
2 protocols using granular lecithin
1
Mebendazole Formulation and Characterization
2
Neutraliser Effectiveness Against P. aeruginosa
Check if the same lab product or an alternative is used in the 5 most similar protocols
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A neutraliser solution containing 1.0 % w/v sodium thiosulphate pentahydrate (ACROS Organics, Loughborough UK), 0.5 % w/v sodium dodecyl sulphate (BDH Laboratory Supplies, poole UK), 1.0 % w/v granular lecithin (ACROS Organics New Jersey US), 15 % w/v of Polysorbate 80 (ACROS Organics Loughborough UK) and 0.1 % w/v L-Histidine (ACROS Organics New Jersey US) was prepared and sterilised by membrane filtration. Efficacy and toxicity of the neutraliser against P. aeruginosa PA14 was evaluated using a suspension challenge method as specified in BS EN 13727 2012+A1 2013. (26)
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