MRI consisted of the following sequences: Sagittal STIR and sagittal and axial T1-weighted sequences before contrast. Following intravenous administration of Gadolinium contrast (Gd-DTPA, 0.2 mmol/ml, GE Healthcare AS, Oslo, Norway) using 0.1 mmol/kg with a maximum of 10 mmol DCE-MRI was obtained using a sagittal T1-weighted spoiled gradient echo sequence with four sagittal slices every 5 s with 50–65 repetitions, repetition time (TR) = 50.2 ms, echo time (TE) = 4.1 ms, field of view (FOV) = 16 cm, slice thickness (ST) = 4 mm, matrix = 128 × 128, flip angle 30° and acquisition time (AT) 4.2–5.4min. Finally, sagittal and axial T1 FS post-contrast sequences were performed using the following parameters: TR = 860 ms, TE = 20 ms, FOV = 16 cm, ST = 4.0 mm, interslice gap (IG) = 0.8 mm, matrix = 512 × 512, total AT 7.2min. DCE-MRIs were missing in 6 of 44 examinations for technical reasons and follow-up analyses could therefore not be performed in 5 patients.
Details of the MRI protocol are described in an additional file (see Additional file